Báo cáo y học: "Immunization with genetically attenuated P52deficient Plasmodium berghei sporozoites induces a long-lasting" pps

... the maintenance of the sterile immu- nity conferred by attenuated plasmodial sporozoites. List of abbreviations used RAS: Radiation -attenuated sporozoites; GAP: Genetically- attenuated parasites; uis: ... immunizations assays, organs collection, non-parenchy mal cells extraction and staining, FACS, data analysis and participated both in the study design and manuscript draft. MRvD, S...

Ngày tải lên: 11/08/2014, 08:21

... was used as the substrate, and the optical density was measured at 492 nm. Statistical analysis All data are presented as the mean ± standard error of the mean unless otherwise indicated. Statistical ... bystander activation of T cells), possible lipopolysaccharide contamina- tion of the antigen preparation does not influence this assay (data not shown). Cells were stained with a viabilit...

Ngày tải lên: 09/08/2014, 14:22

... RNA plasma levels peaked at day 10 with a nadir between days 84 and 125. For analysis n = 16 at day 3 reducing to n = 6 by day 21 as animals were sacrificed, n = 2 at all time points thereafter. ... be anticipated with a lack of activation and proinflamma- tory Th1 responses [63-65]. By contrast, within 3 days of vaccination when the primary viraemia is first detect- able, a dramati...

Ngày tải lên: 13/08/2014, 01:20

... Mrutyunjaya B Bellad 2 , Baburao R Nilgar 2 , Mrityunjay C Metgud 2 and Geeta Durdi 2 Abstract Introduction: Cyclopia is a rare fetal malformation characterized by a single palpebral fissure and ... cases [2]. The severity has a marked variability and ranges from cyclopia to minimal craniofacial dysmor- phism, such as mild microcephaly with a single central incisor [2]. Cyclopia is...

Ngày tải lên: 11/08/2014, 12:20

... block P. aeruginosa lectins PA-I and PA-II as an alter- native approach to reduce airway colonisation with this bacteria. P. aeruginosa lectins PA-I and PA-II that bind to fucose and galactose ... inhalation alone can clear bacteria from the airways without a strong inflammatory response due to physical elimination of P. aeruginosa via the muco- ciliary elevator. On the other hand i...

Ngày tải lên: 03/11/2012, 11:48

... Residual glycopeptides were finally subjected to automated hydrazinolysis in analytical scale. The four oligosaccharide fractions were separately pyridylaminated and designated endoH-PA, PNGaseF-PA, ... (Deisenhofen, Germany). Peptide-N 4 -(N-acetyl-b-glucosaminyl)asparagine amidase A from almond (PNGase A) was from Seikagaku (Tokyo, Japan) and b-galactosidase from jack beans was obtained f...

Ngày tải lên: 31/03/2014, 08:20

... therapy. 45 A further study evaluated allergen sensitivity by inhaled challenge of allergic asthmatic subjects before and after peptide therapy. Again, three dosage groups were used. Treatment was ... this article: A. B. Kay, B.M. Haselden, W.L.G. Oldfield, C. Alexander, M. Tarzi, T.F. Smith, K. Shirley, J. Arbery, A. Verhoef, J. Barkans, and S. Ying. References 1. Akdis M, Verhagen J, Ta...

Ngày tải lên: 08/08/2014, 21:20

... Takayanagi H, Sawada Y, Yamamoto A, Pando MP, Asano T, Verma IM, Oda H, Nakamura K, Tanaka S: Reciprocal role of ERK and NF-kappaB pathways in survival and activation of osteoclasts. J Cell Biol ... Munafo A, Biollaz J: Phar- macokinetics and pharmacodynamics of IFN-beta 1a in healthy volunteers. J Interferon Cytokine Res 2000, 20:857- 866. 28. Miyazaki T, Katagiri H, Kanegae Y, Takayan...

Ngày tải lên: 09/08/2014, 01:23

... and 29 healthy indi- viduals was analyzed to quantify EBV loads. To obtain more accurate data using a semiquantitative PCR method, the PCR reaction was stopped before it reached a plateau state. ... 33:993-1000. 10. Yokochi T, Yanagawa A, Kimura Y, Mizushima Y: High titer of anti- body to the Epstein–Barr virus membrane antigen in sera from patients with rheumatoid arthritis and syst...

Ngày tải lên: 09/08/2014, 01:23

... V, Karabina S -A, Tambaki AP, Bairaktari E, Goude- venos J, Chapman J, Elisaf M, Tselepis A: Atorvastatin preferen- tially reduces LDL-associated platelet-activating factor acetylhydrolase activity ... lipoprotein-associated phospholipase A 2 Evangelia S Lourida 1 , Athanasios N Georgiadis 2 , Eleni C Papavasiliou 1 , Athanasios I Papathanasiou 2 , Alexandros A Drosos 2 and Alexandros...

Ngày tải lên: 09/08/2014, 10:20