Báo cáo y học: " HIV-1 sub-type C chimaeric VLPs boost cellular immune responses in mice" potx

... protection [9], while RT- specific CTLs induce potent Th1 responses in mice, when administered in low doses [13]. This study investigates immune responses induced by chimaeric Gag VLPs incorporating ... GagTN VLPs as vaccine boosts. BALB /c mice were vaccin ated with the DNA vaccine pVRCgrttnC on day 0 and day 28 (DNA+DNA group) or primed on day 0 with the DNA vaccine and boo...

Ngày tải lên: 11/08/2014, 08:21

... persistent infection may participate in airway inflammation. Chlamydial infection activates a cytokine response including basic fibroblast growth factor [38] by smooth muscle cells, and TNF-α secretion ... data indicate that C. pneumoniae infection induces a sustained airway hyperresponsiveness. Airway inflammation To assess whether C. pneumoniae infection induces a change of the inflamma...

Ngày tải lên: 12/08/2014, 15:21

... resulted in a steady increase in plasma cholester ol levels and rendered these mice resistant to diet-induced obesity. In contrast, in the ApoE3 knock -in mice, the efficient catabolism of chylomicron ... & Chen GC (1980) Radioimmunoassay of human arginine-rich apolipoprotein, apoprotein E. Concentration in blood plasma and lipoproteins as affected by apoprotein E-3 deficiency. J...

Ngày tải lên: 17/03/2014, 17:20

... already introduced into clinical practice. Therapeutic targets and strategies to interfere with I/R injury Chemokines/Cytokines Most pro-inflammatory chemokines such as IL-8, MCP- 1, ENA-78, ... glucocorticoid regulated Kinase 1 The serum- and glucocorticoid-inducible protein kinase 1 (SGK1) is a serine-threonine protein kinase activated through the phosphatidylinositol 3-kinase (PI3-kinase)...

Ngày tải lên: 11/08/2014, 06:22

... mono- cytes and the rate of apoptosis of NKT cells decrease; in CAP absolute counts of NK cells, CD4-lymphocytes, CD8-lymphocytes and B-lymphocytes decrease; in intraabdominal infections absolute counts ... patient. Blood was collected into ethyldiamine tetracetic acid (EDTA)-coated tubes (Vacutainer, Becton Dickinson, Cockeysville, MD, USA) and transported to the central laboratory withi...

Ngày tải lên: 13/08/2014, 20:22

... description Variance of rERP No. of Genes Tricarboxylic acid cycle 790 5 Tricarboxylic acid cycle 243 5 Ergosterol biosynthetic process 749 14 Branched chain family amino acid biosynthetic process 207 ... anaerobic (Saccharomyces cerevisiae, Saccharomyces bayanus and Candida glabrata) to aerobic (Aspergillus nidulans, Candida albicans, Debaryomyces hansenii, Kluyveromyces lactis, Yarrowia lip...

Ngày tải lên: 14/08/2014, 21:20

... EV71 vaccines using different approaches are being investi- gated. These include formalin-inactivated whole virus vac- cine, DNA vaccine and recombinant protein vaccine. These vaccine constructs ... an EV71 vaccine is the lack of a suitable animal model for the test- ing of vaccine immunogenicity and efficacy. Laboratory mice are only susceptible to EV71 infection in the first 4 days of lif...

Ngày tải lên: 14/08/2014, 19:22

... Digoxin, Serum concentration, Heart failure, Renal clearance 1. Introduction Cystatin C (Cys -C) is a non-glycosylated cationic protein of 13.3 kDa, belonging to the cystatin superfamily of cysteine ... were participated in this study. The serum levels of Cys -C and Cr in the patients were higher than those in the healthy elderly subjects, but the increase of Cys -C was more pr...

Ngày tải lên: 31/10/2012, 17:08

... glycogen in the intact liver in vivo. Second, during infusion of [1- 13 C] glu- cose, label incorporation was observed not only into the C1 of glycogen but also the C6 , which can only occur by ... determine the potential labeling of the glycogen C2 and C5 resonance due to label scrambling from pyruvate carboxylase/phos- phoenolpyruvate carboxykinase activity (Ôpyruvate recyc- lingÕ...

Ngày tải lên: 17/03/2014, 17:20

... persistent hyperinsulinaemic hypoglycaemia of infancy [12] cluster in this domain of the protein. Persistent hyperinsulinaemic hypoglycaemia of infancy is an hereditary disease char- acterized by inappropriately high levels ... those occurring in SUR1 in persistent hyperinsulinaemic hypoglycaemia of infancy. In a series of elegant studies, Lukacs and colleagues have shown that traffick...

Ngày tải lên: 31/03/2014, 08:20