Báo cáo khoa hoc:" Sporadic ALS is not associated with VAPB gene mutations in Southern Italy" ppt

... number not for citation purposes) Journal of Negative Results in BioMedicine Open Access Brief report Sporadic ALS is not associated with VAPB gene mutations in Southern Italy Francesca Luisa ... Alsin gene located at 2q33 [4]. To date over 100 different missense mutations in the Sod1 gene [5] and up to eight described mutations in the Alsin gene have...

Ngày tải lên: 11/08/2014, 08:20

... Wnt expression is highly variable in this fibroproliferative dis- ease with the only consistent finding being down-regu- lated Wnt 11 mRNA expression in disease tissue. As Wnt- 11 signalling is independent ... the situation in tumors, this region (exon 3) of the β-catenin gene derived from DD samples does not contain such mutations [8]. Given the proposed role of Wnt/β-caten...

Ngày tải lên: 11/08/2014, 08:20

... appetite is increased [10]. Interestingly, it has also been shown that fasting ghrelin is negatively associated with energy intake [25]. In this same study [25], Caucasians had ghrelin concentrations ... after eating [4-6]. Furthermore, ghrelin infusions are associated with feelings of hunger and increased energy intake during a buffet-style lunch [7]. Despite the evidence indic...

Ngày tải lên: 11/08/2014, 08:20

... in the early postoperative phase is probably a normal finding, is not associated with graft infection and can be managed non-operatively. Background Intra-abdominal free gas is a normal finding ... later in the postoperative period following abdominal aortic aneurysm repair is not such a benign finding and is said to be a reliable indicator of graft infection. This compl...

Ngày tải lên: 11/08/2014, 10:22

... subunits into a func- tional protein complex. In the present study, the data indicate that the phytyl chain in Chl is of central importance. Bleaching of the tetrayrrol moiety in Chl maintained the ... for isolation of the dimeric Cyt b 6 f complex. In comparison to BN-PAGE, LN- PAGE is compatible with spectroscopic methods enabling analysis of fluorescent protein complexes after...

Ngày tải lên: 23/03/2014, 07:20

... hMLH1 gene (Human Mutant L homologue 1) is a potential major cause of colon carcinogenesis suggesting that an epigenetic mechanism is underlying tumorogenesis [6]. The term epigenetic is defi ... growth and induces apoptosis. This suggests that hindering UHRF1 to exert its role in the duplication of the methylation patterns (DNA + histones) is responsible for inducing apoptosis....

Ngày tải lên: 10/08/2014, 10:21

... each with its own intrinsic rhythm, partici- pate in this ‘mob action’, and yet a meaningful global outcome emerges. It is fascinating that in systems such as the gut, even isolated muscle tissue preparations ... muscle is freshly dissected and isolated, it usually remains quiescent, and mem- brane potential recordings display a noisy baseline. Confocal Ca 2+ imaging records obtaine...

Ngày tải lên: 16/02/2014, 09:20

... immuno- staining data, this result suggests that there is a population of p48 that is not complexed with p140 during meiosis. Alternatively, the p48 subunit may be unstably associated with the intact ... synthesis during meiosis, the molecular basis is poorly understood. In C. cinereus meiotic cell cycle, premeiotic S-phase and meiotic prophase I are distinguished by the karyo...

Ngày tải lên: 20/02/2014, 11:20

... targets of PtdIns3K include glycogen syn- thase kinase-3 (GSK3) and the mammalian target of rapamycin (mTOR). GSK3 is inactivated in response to insulin via a PtdIns3K ⁄ protein kinase B (PKB)- dependent ... PDC is regulated independently by the main fuel sources in muscle and by insulin through directly altering the expression of the human PDK2 and PDK4 isoforms. In addition to our...

Ngày tải lên: 07/03/2014, 17:20

... [5–7]. Interestingly, the lectin is also expressed in excised leaves after infection with an incompatible Magnapor- the grisea strain [8,9] as well as during senescence [10]. Since Orysata is expressed at ... legume lectin Phaseolus vulgaris agglutinin (PHA) and the GNA-related lectin from snowdrop (Galanthus nivalis agglutinin, GNA) in P. pastoris. A glucose-mannose- binding legume...

Ngày tải lên: 14/03/2014, 23:20