Báo cáo khoa hoc:" Association study with Wegener granulomatosis of the human phospholipase Cγ2 gene" doc

... Central Page 1 of 5 (page number not for citation purposes) Journal of Negative Results in BioMedicine Open Access Research Association study with Wegener granulomatosis of the human phospholipase ... the Genotyper software (ABI) producing a marker-specific allele image profile (AIP, see [21] and [7]). AIP consists of series of peaks with different heights refle...

Ngày tải lên: 11/08/2014, 08:20

... phosphory- lation of the C-terminal SSXS-motif of the R-Smad. Based on the diverse mechanism of Smad activation by either TGF-b1 or NGF, specific subsets of target genes might be induced. The potential of NGF ... TGF-b1inL6 cells and after 1 h of stimulation with NGF in PC12 cells. Referring to Smad4, there are significant levels of protein in the nucleus of both cel...

Ngày tải lên: 16/03/2014, 16:20

... accumulation of cystine in the lysosome [1,2]. During the normal degradation of proteins in the lysosome, cystine, the disulfide-linked form of cysteine, is not reduced in the oxidating environment of the lysosome ... with which these CTNS mutant alle- les can complement ers1D. Importantly, the inability of these mutant ctns alleles to complement ers1D provides the...

Ngày tải lên: 16/03/2014, 18:20

... abolished when the primary antibody was preabsorbed with the specific peptide. Functional expression of the human b 1B subunit with Na V 1.2 in Xenopus oocytes To explore the regulatory function of the human ... the intracellular segment of the b 1 subunit is required for the interaction with the a subunit, probably a crucial step for the regulation of cha...

Ngày tải lên: 16/03/2014, 23:20

... organization of the Cc RNase gene and its derived mRNA isoforms. The rectangles represent the exons and the horizon- tal bold lines the introns. The black parts of the rectangles show the protein-coding ... (NW_001834409:c1450413–1449631). The numbers above the boxes indicate the size of the exons, and those below the lines indicate the size of the intron...

Ngày tải lên: 23/03/2014, 06:20

... genome duplications of the OsCESA/CSL gene family. The scale on the left is in megabases (Mb). The ovals on the chromosomes (vertical bars) indicate the positions of centromeres; the chromosome numbers ... biosynthesis. Almost all OsCESA ge nes are highly expressed in the tissues we examined, confirming their major roles in the biosynthesis of cellulose, the main com...

Ngày tải lên: 11/08/2014, 11:21

... humans [27]. The features of three intergenic DHS demonstrated in the present study correspond well to those of the LCR, so these DHS likely form the LCR of the B29/Ig-b gene, although further examination ... that of the control. The sequence responsible for the major mobility shift and the transc riptional enhancing activity in the 0 .3-kb DNA with the conse...

Ngày tải lên: 24/03/2014, 03:21

... induce the formation of a tight turn (type VIII turn) of the protein backbone [41]. Replacement of the two unpaired cysteine residues with serines did not affect the functional activity of mutant ... [4,5,35,36]. Therefore, to investigate the folding of both hb 2 m and the hFcRn HCs, the configuration of disulfide bonds was qualita- tively investigated using a combin...

Ngày tải lên: 16/03/2014, 06:20

... in the hypothesis, and a counter is augmented by one if they disagree. The WD score between the reference and the hypothesis is equal to the number of discrepancies divided by the number of ... over the utterances in the two corpora. The window has a size equal to half the average segment length. Within the window, the algorithm examines the number of seg...

Ngày tải lên: 17/03/2014, 01:20

... this is a generalization of the method of case frame analysis in which the analysis of the semantic structure of a verb-plus-noun phrase is based on the case-frame of the verb. That is, when ... jinko (" ;the population of the capital of California"), or NP with a relative clause, as in Watashi ga atta hito no na (" ;the name of the person...

Ngày tải lên: 17/03/2014, 20:20