Báo cáo khoa hoc:" TOPBP1 missense variant Arg309Cys and breast cancer in a German hospital-based case-control study" pot

... -AGATTTCAGTAAACACCCCTG-3’ (forward) and 5’ -GGTCTTCAAAGTCAGGCTAG-3’ (reverse) using HotStart Taq DNA Polymerase ( Qiagen) and 35 cycles of 1 min denaturation at 94°C, 1 min annealing at 60°C and 1 min ... in the acquisition of clinical data. TD initiated the study, participated in the analysis and interpretation of data, and drafted the manuscript. All authors read and approve...

Ngày tải lên: 11/08/2014, 07:21

... short chain; Aco1, aconitase 1; Agt ) , alanine-glyoxylate aminotransferase knockout; Aldh2, aldehyde dehydrogenase 2; Car3, carbonic anhydr- ase 3; Cat, catalase; Dao1, D-amino acid oxidase 1; ... Barcelona, Spain) and the images were ana- lyzed with melanie version 5.0 software (GeneBio, Geneva, Switzerland), including spot detection, quantifica- tion, normalization, data analysis and st...

Ngày tải lên: 23/03/2014, 03:20

... of altitude and stand age; these two factors explain 70% of the spatial variability of defoliation and 64% of that of yellowing. In addition, a databasecomposedof178soilanalyticalprofiles was analysed ... follow- ing substrates can be distinguished (table I): – the Vosgian sandstone and conglomerate, very rich in Si (93%) and highly depleted in alkaline and alkaline earth (M...

Ngày tải lên: 08/08/2014, 14:20

... gap fraction, at several zenith angles, enables a calculation of the major structural parameters [ 13, 20]: leaf area index, mean leaf angle and, occasionally, foliage dispersion. Gap ... K value for each ring was calculated in each case, first using the gap fraction averaged over azimuth (K a ), and then from the logarithmic average of the...

Ngày tải lên: 08/08/2014, 14:21

... (Belgium) Summary A large increase in the total phenotypic variance of thorax size was observed in a cage population of Drosophila melanogaster, maintained at 28 °C, a few months ... dozen. In order to ascertain whether that increase in total phenotypic variance was due to an increase in environmental or in genetic variance that popul...

Ngày tải lên: 09/08/2014, 22:23

... receptor antagonist anakinra: a case report Dieter Scholtze 1* , Zsuzsanna Varga 2 and Alexander Imhof 1 Abstract Introduction: Legionellosis is a systemic disease that primarily affects the lungs. ... U/L Aspartate aminotransferase 39 U/L 10-35 U/L Alanine aminotransferase 67 U/L 10-35 U/L g-glutamyl transpeptidase 165 U/L 5-36 U/L Alkaline phosphatase 164 U/L 35-104 U/L Pancreatic amy...

Ngày tải lên: 10/08/2014, 23:21

... pheo- chromocytoma was al so entertained in our patient. Intracardiac pheochromocytoma is very rare. In a report of 32 cases, 19 cases were in the left atrium, seven in the inter-atrial septum and the remaining ... had very high levels of plasma and 24-hour urine catecholamines and metanephrines tests. A (123)I- metaiodobenzylguanidine scan showed intense uptake in the lef...

Ngày tải lên: 10/08/2014, 23:22

... needs to learn thou- sands of Chinese characters. The official agents in Taiwan and China, respectively, chose 5401 and 3755 characters as important basic characters in national standards. Consequently, ... Some take linguistics-based approaches. Pictogram is a major formation of Chinese characters, and radicals carry partial semantic information about Chinese charac- ters....

Ngày tải lên: 19/02/2014, 19:20

... that contains one domain and no disulfide bonds. Its stability in the native state may be maintained mainly by key amino acids. In this study, two point-mutated proteins each with a single base substitution ... investigated. Two point-mutated proteins, with a single base substitution of alanine for tryptophan (W14 0A) and alanine for lysine (K13 3A) , and two truncated fragment p...

Ngày tải lên: 20/02/2014, 01:20

... summarization that important sentences that contain topics in a text have cer- tain positional patterns in a paragraph (Lin and Hovy, 1997), which may apply because reasons like pros and cons in a review ... identifying reasons in online reviews and introduce a novel technique to automatically label training data for this task. We assume reasons in an online revi...

Ngày tải lên: 20/02/2014, 12:20