Báo cáo khoa hoc:" Human haematopoietic stem cells express Oct4 pseudogenes and lack the ability to initiate Oct4 promoter-driven gene expression" ppt
Báo cáo khoa hoc:" Human haematopoietic stem cells express Oct4 pseudogenes and lack the ability to initiate Oct4 promoter-driven gene expression" ppt
... 2008,
389:845-850.
doi:10.1186/1477-5751-9-2
Cite this article as: Redshaw and Strain: Human haematopoietic stem
cells express Oct4 pseudogenes and lack the ability to initiate Oct4
promoter-driven gene expression. Journal of Negative ... lack the ability to initiate Oct4
promoter-driven gene expression
Zoe Redshaw
1*
, Alastair J Strain
2
Abs...
Báo cáo khoa học: "Human embryonic stem cells and therapeutic cloning" pdf
... that lacks T and B cells, can be transformed into
ES cells genetically corrected for the Rag mutation and then
turned into blood progenitors that will generate B and T
cells when reintroduced into ... performed and demonstrated that the cell line originated
from the cloned blastocysts reconstructed from the donor
cells, not from parthenogenetic activation. The statisti...
Báo cáo khoa học: Human delta-lactoferrin is a transcription factor that enhances Skp1 (S-phase kinase-associated protein) gene expression pdf
... from the pCR-
BluntII-TOPO-534 vector as template and religation.
Then, the KpnI–XhoI digest was isolated and cloned into
the pGL3-promoter-Luc reporter vector, leading to the
production of the ... in cells expressing these mutants. They also
observed the formation of multinucleated cells, centro-
some and mitotic spindle abnormalities, and impaired
chromosome segrega...
báo cáo hóa học:" Human embryonic stem cells hemangioblast express HLA-antigens" pot
... stage and then differentiate
into blast cells. The bipotentiality of hemangioblast and
blast cells provides the opportunity to use them in future
cellular therapies of human disorders. Moreover, the ... fetal and embryonic globin genes. Interestingly, these cells expressed also HLA
class I molecules, however at very low levels compared to endothelial and hematopoietic...
báo cáo khoa học: "Genome Medicine: stem cells, genomics and translational research" pptx
...
self-renewal, the generation of more identical cells, and
developmental potency, the capacity to give rise to more
differentiated cells. Stem cells come in different ‘flavors’.
Blood-forming (hematopoietic) ... regarding stem cells rests on
several converging themes. e derivation of ES cells,
first of mouse and then of human origin, provided a
platform for the s...
Báo cáo khoa học: Human kynurenine aminotransferase II – reactivity with substrates and inhibitors potx
... mixture of the PLP and PMP forms
of the enzyme or of enolimine and ketoenamine tau-
tomers of the internal aldimine of PLP [35]. PLP is a
probe of the active site environment, and the tauto-
meric ... converting
the PLP form of the enzyme to the PMP form.
Uncompetitive inhibition involves the exclusive (or
predominant) binding of the inhibitor to the enzyme–
su...
Báo cáo khoa học: Human telomeric G-quadruplex: structures of DNA and RNA sequences ppt
... one strand and only
the 3¢-end G-tract of the other strand [30] (Fig. 3D).
The core of this structure, called the (3 + 1) core, has
three strands oriented in one direction and one strand
oriented ... step toward understanding the structure of
the ‘real’ telomeres is to address the question on the
structure of long human telomeric DNA sequences
[27,37,67,68]. The prob...
Báo cáo khoa học: Human anionic trypsinogen Properties of autocatalytic activation and degradation and implications in pancreatic diseases potx
... subtraction.
Results
Recombinant expression of human anionic trypsinogen
The gene for human anionic trypsinogen was cloned under
the control of the T7 promoter into the pTrap-T7 expression
vector [11,14], that ... have
profound effects on the overall stability of the pancreatic
trypsinogen pool and its susceptibility to autoactivation.
To model these changes in vitro,...
Báo cáo khoa học: Human ATP-dependent RNA ⁄ DNA helicase hSuv3p interacts with the cofactor of survivin HBXIP ppt
... in restoration of apoptotic ability of cancer cells.
To the best of our knowledge no other interactors
of the HBXIP have been reported, nor has its exact
A
B
C
Fig. 4. Expression of hSuv3p lacking ... itself can increase the protein stability.
For these studies the protein decay rates were measured
for the COS-1 cells transfected with the expression vec-
tors encoding the...
Báo cáo khoa học: Hodgkin Reed–Sternberg cells express 15-lipoxygenase-1 and are putative producers of eoxins in vivo Novel insight into the inflammatory features of classical Hodgkin lymphoma ppt
... monocytes,
airway epithelial cells, reticulocytes and mast cells
[6,18–20]. The Th2 cytokines IL-4 and IL-13 induce
the expression of 15-LO-1 in monocytes, airway epithe-
lial cells and mast cells [20–23]. ... L1236 cells (data not
shown). To demonstrate the expression of the 15-LO-1
protein in L1236 cells and the cellular localization of
the enzyme in the p...
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