Báo cáo khoa hoc:" Human spongiosa mesenchymal stem cells fail to generate cardiomyocytes in vitro" doc

... Access Research Human spongiosa mesenchymal stem cells fail to generate cardiomyocytes in vitro Svetlana Mastitskaya and Bernd Denecke* Address: Interdisciplinary Centre for Clinical Research (IZKF) ... cardiac-specific proteins in differentiated cells from all passages, as compared to untreated cells (data not shown). Nonetheless, cells in three-dimensional cu...

Ngày tải lên: 11/08/2014, 07:21

... (MSCs) in an experimental hepatocellular carcinoma (HCC) model in rats and to investigate the possible role of Wnt signaling in hepato-carcinogenesis. Methods: Ninety rats were included in the ... paid to the relation- ship between stem cells and tumor cells. Qiao and coworkers reported that human mesenchymal stem cells (hMSCs) can home to tumor sites and inhibit th...

Ngày tải lên: 10/08/2014, 10:21

... and toluidine blue staining Scoring of slides from immunohistochemical staining of cell- surface markers, ECM proteins and toluidine blue staining of total proteoglycans was performed blinded by ... capable of differentiating into adi- pocytes, chondrocytes and osteoblasts, and, more recently, have been shown to differentiate into insulin-, somatostatin- and glucagon-expressing cells [13...

Ngày tải lên: 09/08/2014, 10:23

... inflammatory mediators in brain infarct area. Significantly higher mRNA expressions of (A) interleukin (IL)-18, (B) toll-like receptor (TLR)-4, and (C) plasminogen activator in- hibitor (PAI)-1 in group ... area. This finding indicates that ADMSCs was able to migrate (i.e. homing) to brain infarcted area after venous injection. Autologous Transplantation of ADMSCs Attenuated Anti-...

Ngày tải lên: 18/06/2014, 16:20

... carriers increased in intraperitoneal tumors. Artificial receptor strategy can be applicable to other cell types, especially to circulating cells lacking native homing abilities. Competing interests The ... increased binding to cells over- expressing erbB2 (40% in experimental group versus 8% in control). The only available study that investigated Figure 5 Kinetics of MSCs hom...

Ngày tải lên: 20/06/2014, 07:20

... two proteins has been not been demonstrated [5,6,17]. Data are emerging that point to perilipin as a key player in directing proteins involved in lipolysis to a subset of lipid droplets [5]. Interestingly, ... PKA phosphorylation induces a conformational change that increases the accessible hydrophobic surface area, enabling freer access to the lipid-binding site, in return for we...

Ngày tải lên: 18/02/2014, 11:20

... Annotations India 7844 United States 5824 Canada 187 United Kingdom 172 Colombia 100 Table 1: Demographic information about annota- tors: top 5 countries represented in our dataset. In total, we ... lexicon links concepts, color terms and emotions to spe- cific RGB values. This lexicon may help to dis- ambiguate objects when modeling conversational interactions in many domains. We ha...

Ngày tải lên: 22/02/2014, 02:20

... mentions to be potentially corefer- ent and examine all possible combinations; only if the system fails to link a mention with an al- ready existing entity, it is considered to be chain starting. 3 However, ... any definite NP occurring in the first sen- tence of a text to be chain starting is very high, since there has not been time to intro- duce many entities, all definites appear...

Ngày tải lên: 08/03/2014, 21:20

... variance in the training data. This is expected, since interpretation performance is not the only factor in uencing the objective outcome: other factors, such choosing the the appropriate tutor- ing ... are trying to model. Thus, the training data for our model consists of 35 instances, each corresponding to a single dia- logue and the learning gain associated with it. We can compute i...

Ngày tải lên: 08/03/2014, 21:20

... read out in a Typhoon imager 9400. Proteins originating from the etioplast are shown in red; proteins originating from the chloroplast are shown in green; proteins present in both membranes in equal ... subunits into a func- tional protein complex. In the present study, the data indicate that the phytyl chain in Chl is of central importance. Bleaching of the tetrayrrol moiety i...

Ngày tải lên: 23/03/2014, 07:20