Báo cáo y học: "Effects of pro-inflammatory cytokines on expression of kynurenine pathway enzymes in human dermal fibroblasts" pot
... abnormalities in the kynurenine pathway of tryptophan degradation. Keywords: human, fibroblast, kynurenine pathway, gene expression, cytokine Introduction The kynurenine pathway (KP) is the main route of ... Access Effects of pro-inflammatory cytokines on expression of kynurenine pathway enzymes in human dermal fibroblasts Linnéa Asp 1 , Anne-Sofie J...
Ngày tải lên: 11/08/2014, 06:23
... studies of disease-related abnormalities in the kynurenine pathway of tryptophan degradation. Keywords: human, fibroblast, kynurenine pathway, gene expression, cytokine Introduction The kynurenine pathway ... 8:25 http://www.journal-inflammation.com/content/8/1/25 Page 7 of 7 RESEARCH Open Access Effects of pro-inflammatory cytokines on expression of kynureni...
Ngày tải lên: 11/08/2014, 03:20
... hydrolysis by 70% whereas ATP hydrolysis was inhibited by only 10%. Inhibition of ADP and ATP hydrolysis by azide was greater when the pH of assay solutions was 6.4. Azide inhibition was diminished if ... chromatogra- phy buffer, buffer containing 0.5 M NaCl, and buffer again. The enzyme was eluted with 50 m M glycine, pH 2.5 containing 0.1% NP-40. Fractions of 1 mL were collected int...
Ngày tải lên: 22/02/2014, 04:20
Báo cáo y học: "Differential Constitutive and Cytokine-Modulated Expression of Human Toll-like Receptors in Primary Neutrophils, Monocytes, and Macrophages" docx
... effects of im- mune-modulating cytokines on protein expression but focused on the effects on TLR mRNA expression. Pro- inflammatory cytokines may also control protein ex- pression of TLRs on the ... cytokines rather than TLR-ligand binding per se. The results of our study demonstrate that several pro-inflammatory cytokines contribute to the regula- tion of TLR...
Ngày tải lên: 08/08/2014, 16:23
Báo cáo y học: "Octacalcium phosphate crystals directly stimulate expression of inducible nitric oxide synthase through p38 and JNK mitogen-activated protein kinases in articular chondrocytes" pps
... IL-1β. Inhibition of iNOS by actinomycin and cycloheximide may reflect, at least in part, inhibition of AP-1 complex synthesis, normally induced by BCP crystals. Conclusion In summary, this study ... and one is inducible (iNOS or NOS-2). Expression of iNOS has been demonstrated in various cell types. Within the joint, chondrocytes may be the main cell source of NO, and iNOS e...
Ngày tải lên: 09/08/2014, 06:23
Báo cáo y học: "Early Differential signaling mechanisms regulate expression of CC chemokine receptor-2 during monocyte maturatio" ppsx
... tissues. PMA-treatment of monocytes induces selective downregulation of CCR2 Based on the above results we decided to further examine the regulation of CCR2 expression in monocyte matura- tion using the human monocyte ... granularity of the cells. In addi- tion, we demonstrated an up-regulation in expression of genes associated with monocyte differentiation, notably C...
Ngày tải lên: 11/08/2014, 08:21
Báo cáo y học: "Wound trauma mediated inflammatory signaling attenuates a tissue regenerative response in MRL/MpJ mice" pot
... chemokine and cytokine synthesis, resulting in resolution of the inflammatory infiltrate. The effects of trauma on healing and tissue regeneration responses may depend upon the stimuli for its induction, ... cleanly cut or altered in configuration by the mice through scratching within a few days of injury were excluded from the study. Typically, in non-injured mice, the circular...
Ngày tải lên: 11/08/2014, 03:20
Báo cáo y học: "Effects of p-Synephrine alone and in Combination with Selected Bioflavonoids on Resting Metabolism, Blood Pressure, Heart Rate and Self-Reported Mood Changes"
... effects on heart rate or blood pressure were observed in response to p-synephrine or p-synephrine in combination with naringin and hes- peridin (Table 2). p-Synephrine differs from ephedrine in ... participants were randomly assigned to one of the five dou- ble-blinded treatment conditions in which they con- sumed one ounce of V-8 juice containing the following ingredient va...
Ngày tải lên: 25/10/2012, 11:04
Báo cáo y học: "Effects of Flurbiprofen on CRP, TNF-α, IL-6, and Postoperative Pain of Thoracotomy"
... evaluating variations in pain intensity. Subjects are instructed to indicate the intensity of the pain by marking a 100-mm line anchored with terms describ- ing the extremes of pain intensity. ... proteins. Proinflammatory cy- tokines induce not only a local inflammation at the site of injury, but also systemic responses such as tachycardia, tachypnea, leukocytosis, and pyrexia (1...
Ngày tải lên: 25/10/2012, 11:10
Báo cáo y học: "Effects of Losartan on expression of connexins at the early stage of atherosclerosis in rabbits"
... Beyer EC, Saffitz JE. Effects of angiotensin II on expression of gap junction channel protein connexin43 in neonatal rat ventricular myo- cytes. J Mol Cell Cardiol. 1998; 32: 800-7. 15. Polontchouk ... 4 and 5 independently showed the pro- tein expression of Cx43 and Cx40 in the iliac arteries of different groups. Figure 1. Hematoxylin/eosin staining of the ili...
Ngày tải lên: 26/10/2012, 09:39