... Yabe H, Fukuma M, Urano F, Yoshida K, Kato S, Toyama Y, HataJ, Umezawa A: Lack of matrix metalloproteinase (MMP)-1 and -3 expression in Ewing sarcoma may be due to loss of acces-sibility of ... family membersshow differential use of Smad3 as a co-activator.The ability of Ets-1 to increase target gene expression maydepend on PKC [22], a pathway previously shown to beinvolved in CCN2 expression ... CCN2, encoded by an immediate-early gene that also promotes cell adhesionand migration and angiogenesis [2,40,41]. Conversely, type Icollagen is induced by Ets-1 but repressed by Fli-1[30,34,42]....