Báo cáo y học: " Adipokine resistin predicts anti-inflammatory effect of glucocorticoids in asthma" pps

... resistin and adip- sinareproteinmediatorssecreted by adipocytes and macrophages within the adipose tissue [3]. Leptin and resistin are usually pro-inflammatory, while adiponectin has mainly anti-inflammatory ... Journal of Inflammation 2011, 8:12 http://www.journal-inflammation.com/content/8/1/12 Page 2 of 7 RESEARCH Open Access Adipokine resistin predicts anti-inflammatory...

Ngày tải lên: 11/08/2014, 03:20

... within the adipose tissue [3]. Leptin and resistin are usually pro-inflammatory, while adiponectin has mainly anti-inflammatory properties [3]. Leptin levels increase in obesity [4] and leptin ... favourable anti-inflammatory activ ity of fluticasone, we studied the effects of this adipokine on human THP-1 macrophages. Interestingly, resistin (0.1 - 2 μg/ml) increased producti...

Ngày tải lên: 11/08/2014, 06:22

... were prospectively included in this study. Patients with an injury severity score <16 points were excluded. In addition, patients with a history of steroid use, anti-inflammatory treatment or ... CC Jr: Jack A. Barney Resident Research Award winner. The inflammatory profile of interleukin-6, interleukin-8, and sol- uble intercellular adhesion molecule-1 in postinjury multiple o...

Ngày tải lên: 13/08/2014, 23:20

... ±Birk protease inhibitors [5], metallothioneins [6], prothymosin a [7], a bacterial ®bronectin-binding protein [8], the brain protein a-synuclein together with the related proteins b-synuclein and c-synuclein ... a globular protein c ontaining a similar number o f residues, as observed in the caseins [3], synucleins [10], tau [14], prothymosin a [7] and the ®bronectin-binding protein [8], a...

Ngày tải lên: 21/02/2014, 15:20

... existense of three dinstict domains, namely: the highly conserved J domain consisting of approximately 70 amino acids a nd known to mediate the hsp70 binding; the glycin e/phenylalanine (G/F) rich ... but significant amounts of the protein can be detected mainly in the cytoplasm. However a larger quantity of the protein seems to accumulate in the nucleus and especially in the nuc...

Ngày tải lên: 17/03/2014, 17:20

... some circumstances. For instance, it increases the inactivation of a 1 -antiproteinase [51] and alcohol dehydrogenase [52] induced by hydroxyl radicals, and the oxidation of LDL mediated by peroxynitrite [53]. ... present 1 h after of Cu 2+ addition, whereas it was entirely consumed in the absence of ferricytochrome c. Finally, in order to specify the role of copper on the pro-o...

Ngày tải lên: 31/03/2014, 08:20

... reduced in offspring with higher order, indicating that the sibli ng effect may have it s ori- gin in utero [12], before an y hygiene effect in early childhood could affect the offspring. In addition, ... allergy or hay fever. It is defined operationally by elevations in serum levels of immunoglobulin E (IgE) reactive with allergens or skin test reactivity to allergens [1]....

Ngày tải lên: 08/08/2014, 21:20

... the need for a continuing training of clini- cians in this type of condition, reviewing the criteria for referral to specialists. Also, it should encourage training in prescribing the most suitable ... prevalence in the general population of chronic pain in the Pain in Europe survey was 19% [50], which is in contrast with the 46.7% of patients with GAD suffering pain for t...

Ngày tải lên: 09/08/2014, 01:21

... spontaneously develop peripheral polyarthritis that resembles human RA in many clinical and pathological respects. This surprising finding induced intense research into the pathophysiology of arthritis in ... glycolytic enzyme G6PI specifically induces arthritis, with no other symptoms of organ-specific or systemic autoimmune disease. Interestingly, although GPI is ubiquitously expres...

Ngày tải lên: 09/08/2014, 06:22

... articular cartilage. The increased frequency of osteo- arthritis with aging indicates the complex etiology of this disease, which includes pathophysiology and joint stability including biomechanics. ... death in a variety of cell types including articular chondrocytes in the joint. There are three isoforms of TGF-β, designated TGF-β 1 , TGF-β 2 , and TGF-β 3 , in mice and humans...

Ngày tải lên: 09/08/2014, 07:20