Báo cáo y học: "Increased levels of circulating Annexin A5 in Familial Mediterranean fever" pps

... characterized by the increased levels of circulating Annexin A5, which is higher in patients within the attack and which associate with the increased levels of C-reactive protein and interleukine-1b ... regular colchicine treatment sufficiently decreases the rate of apoptosis in familial Mediterranean fever patients by affecting the intensity of autoinflammatory react...

Ngày tải lên: 11/08/2014, 06:22

... based upon flow-cytometry data indicating increased rate of apoptosis of subpopulations of leukocytes involved in autoinflammation and recur- rent episodes of fever in FMF [7]. In addition, our ... 57(2):171-177. doi:10.1186/1476-9255-7-55 Cite this article as: Boyajyan et al.: Increased levels of circulating Annexin A5 in Familial Mediterranean fever. Journal o...

Ngày tải lên: 11/08/2014, 03:20

... consumed by sPLA2. This enzyme is increased in level and activity in some inflammatory diseases and catalyzes hydrolysis of aminophos- pholipids, including PS, as well as phosphatidylcholine and phsophatidylethanolamine, ... nega- tive controls of annexin V ligation were used: MPs incubated with annexin V in a calcium-free buffer (to prevent annexin V ligation to PS) or withou...

Ngày tải lên: 09/08/2014, 14:22

... smokers), included in the study, are shown in table 1. Healthy individuals were slightly younger than the COPD patients, which was mainly caused by the young age of the healthy smokers. Addition- ally, ... counted using a Sysmex pocH-100i cell counter (Sysmex, Roche, Germany). Cells were used for flow cytometry and immu- nocytochemical staining on cytospins. Flow cytometry analysis Two...

Ngày tải lên: 12/08/2014, 14:20

... not shown). Since inflammation may be playing a role in progression of atherosclerosis, we examined whether the erythrocyte sedi- mentation rate (as a continuous variable) at the time of PMR diagnosis ... PMR have laboratory evidence of an acute phase response, includ- ing elevation of the erythrocyte sedimentation rate and C-reac- tive protein (CRP). Synovitis in proximal joints...

Ngày tải lên: 09/08/2014, 14:20

... 3 Representative analysis of intracellular Cytotoxic T Lymphocyte Antigen- 4 (CTLA-4) expression in peripheral blood lymphocyte subsetsRepresentative analysis of intracellular Cytotoxic T Lymphocyte Antigen- ... between soluble Cytotoxic T Lymphocyte Antigen- 4 (sCTLA-4) and clinical index of disease activity Bath Ankylosing Spond-ylitis Disease Activity Index in 165 patients with s...

Ngày tải lên: 09/08/2014, 14:22

... details 1 Department of Microbiology and Infectious Diseases, University of Calgary, Calgary, Alberta, Canada. 2 Department of Pathology and Laboratory Medicine, University of Calgary, Calgary, Albe rta, ... patients and were involved in writing the paper. KN and KC were involved in designing the methods for collecting, analyzing and interpreting data, and helped putting the data...

Ngày tải lên: 13/08/2014, 01:20

... ventricular hypertrophy and mortality–results from the Framingham Study. Cardiology 1992, 81:291-298. 4. Dorn GW, Force T: Protein kinase cascades in the regulation of cardiac hypertrophy. J Clin Invest ... protein kinase C, in the development of heart failure. DAG kinase (DGK) acts as an endogenous regulator of GPCR signaling pathway by catalyzing and regulating DAG. Expressions o...

Ngày tải lên: 10/08/2014, 09:21

... retinol binding protein-4 levels in healthy women. Obesity 2007; 15: 2225-32. 71. Jia W, Wu H, Bao Y, et al. Association of serum retinol-binding protein 4 and visceral adiposity in Chinese ... changes in insulin sensitivity. J Clin Endocrinol Metab 2007; 92: 2330-5. 173. Takebayashi K, Suetsugu M, Wakabayashi S, et al. Retinol binding protein-4 levels and clinical features...

Ngày tải lên: 08/08/2014, 17:20

... and healthy control individuals, although interpreta- tion of this finding is limited by the inability of the anti-CD32 antibody to distinguish the activating FcγRIIa and inhibitory FcγRIIb. ... studies involving FcγRII/ Figure 4 Effect of medications and cytokines on FcγRI/CD64 expression by circulating monocytesEffect of medications and cytokines on FcγRI/CD64 expression by circu...

Ngày tải lên: 09/08/2014, 01:22