Báo cáo y học: "HE3286, an oral synthetic steroid, treats lung inflammation in mice without immune suppression" pot

... confirms an anti-inflammatory activity of HE3286 relevant to lung inflammation. Our observations that HE3286 possesses significant anti-inflammatory activity in both carrageenan and LPS- induced lung ... 7:52 http://www.journal -inflammation. com/content/7/1/52 Page 2 of 10 RESEARC H Open Access HE3286, an oral synthetic steroid, treats lung inflammation in mice w...

Ngày tải lên: 11/08/2014, 06:22

... HE3286, an oral synthetic steroid, treats lung inflammation in mice without immune suppression. Journal of Inflammation 2010 7:52. Submit your next manuscript to BioMed Central and take full advantage ... 7:52 http://www.journal -inflammation. com/content/7/1/52 Page 5 of 10 RESEARC H Open Access HE3286, an oral synthetic steroid, treats lung inflammation...

Ngày tải lên: 11/08/2014, 03:20

... investigated mainly in patients with already reduced lung function. Thus, aim of this analysis is to determine whether hypertension and antihypertensive medication have an adverse effect on lung ... Myocardial Infarction Registry, Augsburg, Germany. 8 Ludwig-Maximilians-University, Institute of Medical Data Management, Biometrics and Epidemiology, Munich, Germany. 9 Ludwig-Maximilians...

Ngày tải lên: 25/10/2012, 10:45

... meta- choline (Acetyl-β methylcholine chloride, Sigma) was assessed 24 hours after the last intranasal challenge. Briefly, mice were maintained inside a whole-body plethysmograph (Buxco, Troy, NY) ... to naïve mutant mice, increases in airway resistance were also increased to levels exhib- ited in wild type mice. Thus, Th2 effector responses leading to changes in airway resista...

Ngày tải lên: 03/11/2012, 11:24

... haematoxy- lin and eosin or safranin O fast green. Inflammation was graded on a scale from 0 (no inflammation) to 3 (severely inflamed joint) based on infiltration by inflamma- tory cells in the synovium. ... one of the predominant β1 integrins expressed by rheumatoid syno- vial pannus and is expressed by cells in the intimal lining layer and endothelial cells, especially in venules...

Ngày tải lên: 09/08/2014, 08:22

... tissues We investigated JAM-C expression in human OA and RA syn- ovial samples by IHC using polyclonal antibodies against human JAM-C. Interestingly, expression of JAM-C was mainly found in the lining ... transfer-induced arthritis. JAM-C was expressed by synovial fibroblasts in the lining layer and associated with vessels in the sublining layer in human and mouse arthritic synovial...

Ngày tải lên: 09/08/2014, 10:20

... produced mainly in white adipose tissue and may be the linkage between obesity and insulin resistance. In humans, the role of resistin is not yet fully established. There is evidence that resistin has ... resistin and inflammation. In our study, serum levels of creatinine remained a significant variable to resistin in the multiple regres- sion analyses. Whether this is due to high sy...

Ngày tải lên: 09/08/2014, 10:22

... predominant clade of closely related C. albicans strains that represents almost 40% of all isolates worldwide, as determined by DNA fingerprinting [7] and multi-locus sequence typing (A. Tavanti, ... Candida albicans ALS5, ALS1 and ALS9. Microbiology 2003, 149:2947-2960. 16. Kohler JR, Fink GR: Candida albicans strains heterozygous and homozygous for mutations in mitogen-activated protein k...

Ngày tải lên: 09/08/2014, 20:20

... staining compares the relative intensity of staining of onecoreofaTMAtothatofacontrolcoreonthe same slide. A score of 1 indicates faint staining, 2 indi- cates medium intensity staining, and 3 indicates ... of interest were malignant and originating in the thoracic cavity. Tissues containing a known or suspected malignancy were obtained during standard clinical care through a biopsy or surg...

Ngày tải lên: 10/08/2014, 09:22

... characterized by terms associated to immune response, whereas the rest are mainly involved in metabolic process and system development. Time Varying Dynamic Bayesian Network Modeling A Time Varying Dynamic ... response mechanism undergoes significant restructuring the first days after viral invasion and the TV-DBN succeeded in Table 3 KEGG Pathway analysis (Continued) 24 Cytokine-cytoki...

Ngày tải lên: 10/08/2014, 09:22