Ecosystems and Human Health - Chapter 11 pptx
... and D. purpura ) are the com- mercial source of medicinal digitalis. Many garden plants possess similar active components, including lily-of-the-valley, star-of-Bethlehem, and ole- ander. ... angusticeps ), alpha-den- drotoxin blocks certain voltage-gated K + channels and beta-dendro- toxin blocks certain voltage-gated K + channels in synaptosomes and smooth muscle...
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... such as -NH 2 , -OH, -SH, or -COOH. The oxidation reactions include N- and O-dealkylations, side-chain and aromatic hydroxylations, N-oxidation and hydroxylation, sulfoxide formation, and desulfuration. ... environmental hazards — both man- made and natural — and with the risks to human health that they pose. It is designed such that topics are generally introduced in the...
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... Escherichia coli, Yersinia enterocolitica and Vibrio parahaemolyt- icus, Lancet, 336, 111 1 111 5, 1990. Edelstein, M.R., Contaminated Communities: The Social and Psychological Impacts of Residential ... additives in Chapter 8). Both the EPA and the Envi- ronmental Health Directorate of Health and Welfare Canada have set maximum acceptable limits for toxicants in drinking water...
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Ecosystems and Human Health - Chapter 9 pptx
... diquat. O 2 N CHCH 2 CH 3 CH 3 NO 3 OH O 2 N CH 3 NO 2 OH DINOSEB ( 2-sec-buty 1-4 , 6-dinitropheno1 ) DNOC ( 4, 6-dinitro-o-cresol ) H 3 CCH 3 NN ++ PARAQUAT DIQUAT DIBROMIDE NN + + 2Br - ©2001 CRC Press LLC Nonspecificity Broad-spectrum pesticides, ... all use in 1987. 4,6-Dinitro- o -cresol (DNOC, see Figure 35) has caused acute poisoning in humans with signs and symptoms i...
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Ecosystems and Human Health - Chapter 2 pps
... detecting one breast cancer through annual mammography in 4 0- to 50-year-old women has been esti- mated at $144,000. In the 5 5- to 65-year-old group, it drops to $90,000. Legislators are required ... risk factor (i.e., of human origin). Risk assessment and carcinogenesis As already noted, this is the most complicated and least reliable area regard- ing the prediction of risk...
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Ecosystems and Human Health - Chapter 4 potx
... formaldehyde gas (see Chapter 2), other toxic chemicals, particulates such as asbestos fibers and fiberglass wool, and radon-source ionizing radiation (see Chapter 12). Airtight houses and build- ings, constructed ... reach 30 mps. Micro- scopic particles are retained for 1 or 2 months in the upper and mid-tropo- sphere and about 1 week in the lower troposphere (<1 mi). Airborn...
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Ecosystems and Human Health - Chapter 5 doc
... rapidly and well absorbed from the gastrointes- tinal tract, metabolized through dihalocarbonyl compounds via the cyto- chrome P450-dependent, mixed-function oxidases to CO 2 and CO, and elim- inated ... 2,3,7,8-tetrachlorodibenzo- p - dioxin (TCDD = dioxin). Agent Orange, used as a defoliant in Vietnam, was equal parts of 2,4,-D and 2,4,5,-T and contained TCDD as a cont...
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Ecosystems and Human Health - Chapter 6 pps
... metallothioneins (MTs) based on their amino acid sequences. MT-I and MT-II are the most widely distributed, while MT-III and MT-IV are restricted to neuronal and squamous epithelial cells. MTs have a high affinity ... copper, mercury, and zinc. Such induction makes them important defenses against heavy-metal poisoning, and experiments with knockout mice have shown that the absence of...
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Ecosystems and Human Health - Chapter 7 pps
... been demonstrated. The group includes toluene (1-methylbenzene) and the xylenes (1, 2-, 1, 3-, and 1,4-dimethylbenzene), as well as ethylbenzene and cumene (isopropylbenzene). Dinitrobenzene is ... complex mixtures having nitro- gen- and sulfur-containing elements (e.g., gasoline and other petroleum- based products). Industrially, the uses of solvents are many and varied. They...
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Ecosystems and Human Health - Chapter 8 pdf
... conditions of husbandry and hygiene. The effect was confirmed later for other antibiotics and the mech- anism remains elusive. There is by now a long list of antibiotics and other anti-infective agents ... rBGH produce more of the natural hormone peptide insulin-like growth factor-1 (IGF-1), and IGF-1 is secreted in milk. Increased blood levels of IGF-1 have been associated with an inc...
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