Ecosystems and Human Health - Chapter 6 pps
Ecosystems and Human Health - Chapter 6 pps
... metallothioneins (MTs) based on their amino acid sequences. MT-I and
MT-II are the most widely distributed, while MT-III and MT-IV are restricted
to neuronal and squamous epithelial cells. MTs have a high affinity ... form mercaptides (i.e., X-Hg-SR and
HgSR
2
, where X = an electronegative radical and R = a protein). Organic
mercurials such as methylmercury form mercaptides, R-H...
Ecosystems and Human Health - Chapter 2 pps
... detecting one breast cancer
through annual mammography in 4 0- to 50-year-old women has been esti-
mated at $144,000. In the 5 5- to 65 -year-old group, it drops to $90,000.
Legislators are required ... risk
factor (i.e., of human origin).
Risk assessment and carcinogenesis
As already noted, this is the most complicated and least reliable area regard-
ing the prediction of ri...
Ecosystems and Human Health - Chapter 7 pps
... been demonstrated. The group includes toluene
(1-methylbenzene) and the xylenes (1, 2-, 1, 3-, and 1,4-dimethylbenzene), as
well as ethylbenzene and cumene (isopropylbenzene).
Dinitrobenzene is ... complex mixtures having nitro-
gen- and sulfur-containing elements (e.g., gasoline and other petroleum-
based products).
Industrially, the uses of solvents are many and varied. They...
Ecosystems and Human Health - Chapter 10 pps
... filamentous), spore-forming fungi that also con-
stitute a health hazard and which have historic, pharmacological signi -
cance, but they are considered separately in Chapter 11.
Some human health problems ... rat) and birds and is therefore viewed
as a potential human teratogen. Acute effects in animals (including swine
and poultry) include renal and hepatic destructi...
Ecosystems and Human Health - Chapter 1 pptx
... such as
-NH
2
, -OH, -SH, or -COOH. The oxidation reactions include N- and
O-dealkylations, side-chain and aromatic hydroxylations, N-oxidation and
hydroxylation, sulfoxide formation, and desulfuration. ... susceptible to drug-induced hemolytic anemia include
glucose -6 phosphate dehydrogenase (G -6 - PD) deficiency and sickle cell ane-
mia. A host of drugs, including antimalari...
Ecosystems and Human Health - Chapter 3 pptx
... extreme and there may be short- or long-term effects
on human health. Usual disposal methods for these substances include surface
impoundments used in industry (45–55%), landfill sites (domestic and ... could be found. The PCB fire at St. Basile-le-Grand, Quebec, and the
©2001 CRC Press LLC
Toxicants in the Great Lakes: implications for human health
and wildlife
While the G...
Ecosystems and Human Health - Chapter 4 potx
... in com-
parison to 49 36 deaths from breast cancer, 362 2 from prostate cancer, 3 064
from motor vehicle accidents, and 66 5 from malignant melanoma. Air pol-
lution obviously is an important health ... formaldehyde gas (see Chapter 2), other
toxic chemicals, particulates such as asbestos fibers and fiberglass wool, and
radon-source ionizing radiation (see Chapter 12). Airtight h...
Ecosystems and Human Health - Chapter 5 doc
... receptor and a basic helix-loop-helix-
protein,
Science
, 252, 924–925, 1991.
Landers, J.P. and Bunce, N.J., The Ah receptor and the mechanism of dioxin toxicity,
Biochem. J.
, 2 76, 273–278, ... rapidly and well absorbed from the gastrointes-
tinal tract, metabolized through dihalocarbonyl compounds via the cyto-
chrome P450-dependent, mixed-function oxidases to CO
2
a...
Ecosystems and Human Health - Chapter 8 pdf
... percep-
tions and beliefs regarding herbal therapies, Pharmacotherapy, 20, 83–87, 2000.
Baily-Klepser, T. and Klepser, M.E., Unsafe and potentially safe herbal therapies, Am.
J. Health- Syst. ... absorption of recombinant human
insulin-like growth factor-I in rats, J. Pharmacol. Exper. Ther., 283, 61 1 61 8, 1997.
Klassen, C.D., Amdur, M.O., and Doull, J., Eds., Casarett and Dou...
Ecosystems and Human Health - Chapter 9 pptx
... diquat.
O
2
N
CHCH
2
CH
3
CH
3
NO
3
OH
O
2
N
CH
3
NO
2
OH
DINOSEB
( 2-sec-buty 1-4 , 6- dinitropheno1 )
DNOC
( 4, 6- dinitro-o-cresol )
H
3
CCH
3
NN
++
PARAQUAT DIQUAT DIBROMIDE
NN
+
+
2Br
-
©2001 CRC Press LLC
Nonspecificity
Broad-spectrum pesticides, ... all use in 1987.
4 , 6- Dinitro-
o
-cresol (DNOC, see Figure 35) has caused acute poisoning
in humans with signs and sym...
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