Ecosystems and Human Health - Chapter 5 doc

... Pharmacol. Toxicol ., 35, 307–340, 19 95. Johnson, E.F., A partnership between the dioxin receptor and a basic helix-loop-helix- protein, Science , 252 , 924–9 25, 1991. Landers, J.P. and Bunce, N.J., ... rapidly and well absorbed from the gastrointes- tinal tract, metabolized through dihalocarbonyl compounds via the cyto- chrome P 450 -dependent, mixed-function oxidases to CO...

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... jumping species barriers, espe- cially from animals to humans. Recently, the Marburg virus and the Ebola virus have emerged as life-threatening infections of humans and are believed to have originated ... response, The Sciences , 34 (3), 7 and 51 52 , 1994. Fisher, D.E., Fire and Ice: The Greenhouse Effect, Ozone Depletion and Nuclear Winter . Harper and Row, New York,...

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... reached 1 .5 ppm. The standard set by the U.S. Office of Safety and Health Administration (OSHA) is 1 ppm for the Short Term Exposure Level (STEL), which has a 1 5- min limit. The CO reached 150 ppm and ... symptoms and a more rapid time-to-onset. Seafoods that could be respon- sible include shellfish (diarrhetic shellfish poisoning, paralytic shellfish poi- soning) and scalefish (scomb...

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... such as -NH 2 , -OH, -SH, or -COOH. The oxidation reactions include N- and O-dealkylations, side-chain and aromatic hydroxylations, N-oxidation and hydroxylation, sulfoxide formation, and desulfuration. ... A semi-logarithmic plot (response vs. log-dose) of the dose–response curve shown in Figure 7. Log of Dose Dose-Response as Semi-Log Plot % Maximal Response -1 .0 -0 .5...

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... detecting one breast cancer through annual mammography in 4 0- to 50 -year-old women has been esti- mated at $144,000. In the 5 5- to 6 5- year-old group, it drops to $90,000. Legislators are required ... risk factor (i.e., of human origin). Risk assessment and carcinogenesis As already noted, this is the most complicated and least reliable area regard- ing the prediction of...

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... extreme and there may be short- or long-term effects on human health. Usual disposal methods for these substances include surface impoundments used in industry ( 45 55 %), landfill sites (domestic and ... acid herbicides The chlorphenoxy acid herbicides 2,4-D and 2,4 , 5- T have been widely used on lawns and along road and railway rights-of-way. They mimic plant growth hormones...

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... monoxide, Science, 263, 158 7– 159 3, 1994. Oelermans, J. and Fortuin, J.P.F., Sensitivity of glaciers and small ice caps to green- house warming, Science, 258 , 1 15 117, 1992. Planet Earth — Problems and Prospects. ... breath and flu-like symptoms such as fatigue, muscle and joint pain, and general malaise 4. A 30% annual occurrence of absenteeism due to respiratory illnesses 5....

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... metals, Handbook of Exper. Pharmacol ., 1 15, 121–137, 19 95. Clarkson, T.W., Molecular and ionic mimicry of toxic metals, Annu. Rev. Pharmacol. Toxicol ., 32, 54 5 57 1, 1993. Corey-Slechta, ... metallothioneins (MTs) based on their amino acid sequences. MT-I and MT-II are the most widely distributed, while MT-III and MT-IV are restricted to neuronal and squamous epitheli...

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... Safety and Health (NIOSH) was solicited. Q. What analysis might next be called for? Q. What steps might you recommend in the interim? Case studies 15 and 16 Cast study 15 A 52 -year-old ... Occup. Health and Safety Can ., 5, 28–33, 1989. Klassen, C.D., Amdur, M.O., and Doull, J., Eds., Casarett and Doull’s Toxicology: The Basic Science of Poisons , 5t...

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... M.E., Unsafe and potentially safe herbal therapies, Am. J. Health- Syst. Pharm., 56 , 1 25 138, 1999. Boullata, J.L. and Nace, A.M., Safety issues with herbal medicine, Pharmacotherapy, 20, 257 –269, ... rBGH produce more of the natural hormone peptide insulin-like growth factor-1 (IGF-1), and IGF-1 is secreted in milk. Increased blood levels of IGF-1 have been associated with an incr...

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