Báo cáo y học: " Leukocyte oxygen radical production determines disease severity in the recurrent Guillain-Barré syndrome" ppt
Báo cáo y học: "Leukocyte oxygen radical production determines disease severity in the recurrent Guillain-Barré syndrome" doc
... as: Mossberg et al.: Leukocyte oxygen radical production determines disease severity in the recurrent Guillain-Barré syndrome. Journal of Inflammation 2010 7:40.Submit your next manuscript to ... RGBS.Methods: Oxygen radical production in leukocytes was induced by formyl-Met-Leu-Phe (fMLF), Trp-Lys-Tyr-Met-Val-Met-NH2(WKYMVM), or phorbol myristate acetate (PMA) and assessed by quantifying superoxide ... respiratory burst in leukocytes is strongly associated with a severe course ofRGBS.Introduction The recurrent Guillain-Barré syndrome ( RGBS) is ademyelinating disease of the peri pheral nervous systemcharacterized...
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Báo cáo y học: " Leukocyte oxygen radical production determines disease severity in the recurrent Guillain-Barré syndrome" ppt
... as: Mossberg et al.: Leukocyte oxygen radical production determines disease severity in the recurrent Guillain-Barré syndrome. Journal of Inflammation 2010 7:40.Submit your next manuscript to ... supplementarymechanism relates to the regulatory effects of oxygen radicals on T cells and other subsets of lymphocytes.Phagocyte-derived oxygen radicals efficiently triggerapoptosis in CD4+and ... shown).DiscussionA main finding in this study was that superoxide anion production by leukocytes in response to NA DPH oxi-dase-activa ting peptides was associated wit h severity of disease in patients...
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Báo cáo y học: " Clinical and economic ramifications of switching antipsychotics in the treatment of schizophreniab" pptx
... discontinued the medication to which they were ini-tially randomized at any time during the study and initi-ated therapy with a different antipsychotic within 14 daysof discontinuation of the initial ... of the findings within patient groups based onprior therapy.By design, clinical data were gathered only at specificassessment points throughout the year, limiting our abil-ity to assess clinical ... after leaving the study, a sensitivityanalysis was performed in which only patients who com-pleted the study were included. Furthermore, because the study's outcome measures involved the occurrence...
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Báo cáo y học: "Differentiating midazolam over-sedation from neurological damage in the intensive care unit" pptx
... stopped. In the remaining two patientsno other clinical cause of the coma was apparent. The only other agent used routinely in these patients that couldhave significantly contributed to their ... 1-OHMG individually based ontheir isotopic patterns. The studies were performed on the basis of clinical need, and in all cases they were requested by the consultant intensivist, normally during the ... sedation therapy by continuous intravenous infu-sion and in whom neurological damage was considered clini-cally possible (e.g. a hypoxic event was noted during cardiacsurgery). The mean age of these...
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Báo cáo y học: "Acute oxygen sensing: diverse but convergent mechanisms in airway and arterial chemoreceptors" potx
... P-domains, weakly inward rectifying K2Pchannel’) — amember of the newly emerging gene family of voltage-insensitive tandem P-domain K+(K2P) channels [28]. The importance of maxi-K in transducing ... provides the upstream signal for K+channel inhibition has been thor-oughly investigated and largely discounted by most inves-tigators in the CB field; the haem hypothesis has gainedgreater ... Chemo-transduction in the carotid body: K+current modulated by pO2 in type I chemoreceptor cells. Science 1988, 241:580–582.10. Youngson C, Nurse C, Yeger H, Cutz E: Oxygen sensing in airway chemoreceptors....
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Tài liệu Báo cáo Y học: A family of expressed antifreeze protein genes from the moth, Choristoneura fumiferana ppt
... as w ell as synthesizing A FPs, spin asilk hibernaculum, which may prevent inoculative freezing.During the winter they also increase the concentration of the cryoprotectant, glycerol, 10-fold ... seen in the blotwashed at low stringency, verifying this procedure.After washing at low stringency, approximately 17 bands(consistent with the number of hybridizing plaques/genome in the library ... lines indicate the co ding regions of the AFP genes, and horizontal thin lines, r egions sharing homology withcDNA untranslated regions. The dashed horizontal line for the gene2.7a ind icate s the...
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Báo cáo Y học: Two 1 : 1 binding modes for distamycin in the minor groove of d(GGCCAATTGG) docx
... may be spoiled by inaccuratepositioning of the interacting groups. The contact area of the distamycin amidinium end wasinvestigated by evaluating the hydrogen positions andinteraction energy ... These confirmed that in the refined crystal geometry the drug is rather too tightlypacked against the G19 base. The interaction can beimproved by locally relaxing the drug geometry, but nohydrogen ... one crystal the distamycin orientation and binding site is the same as in 12-dista, the orientation of the drug is inverted in the other crystal. Both orientations show interactions betweenthedrugandguanineNH2groups....
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Báo cáo y học: "Familial Polycythemia Caused by a Novel Mutation in the Beta Globin Gene: Essential Role of P50 in Evaluation of Familial Polycythemi" potx
... substitutions affecting this interface. All these substitutions can affect the cooperative nature of oxygen binding with heme, and in turn, can change the affinity of Hb for oxygen. The majority of mutations ... deoxygenation of hemoglobin occur at the heme iron. The sigmoid shape of Hb -oxygen dissociation curve is indicative of cooperative interaction between heme and oxygen. Oxygen affinity and ... other symptoms. Past medical history was unremarkable. Family history was significant for lifelong history of polycythemia in her mother, maternal grandmother and her younger sister. Physical...
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Báo cáo y học: "Fat-Storing Multilocular Cells Expressing CCR5 Increase in the Thymus with Advancing Age: Potential Role for CCR5 Ligands on the Differentiation and Migration of Preadipocytes" pot
... cells in the septa and inside the thymic pa-renchyma. These data reinforced the hypothesis that adipocytic mesenchymal cells could be possibly im-migrating and/or differentiating in the aging ... Within the young thymus, several cell types have been described as playing a role in thymic physiology including thymocytes, thymic epithelial cells, dendritic cells, fibroblasts, mesenchymal ... simply fill a space left by the thymic lymphoid compartment or replace the lymphocytic perivascular space. In the present study, we defined not only thymic unilocular adipocytes in the thymus...
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Báo cáo y học: "Clinical use of a modified release methylphenidate in the treatment of childhood attention deficit hyperactivity disorder" pps
... impulsivity. The P4 was designed by one of the consultant child psychiatrists in the team and has been in use for 15 years as one of the tools available for screening the core symptoms of ADHD. The ... used in everyday clinical practice are needed. Challenges in clinical practice In the specialist ADHD clinic in East and North Hertfordshire, UK, assessment is by use of the P4 screening ... atomoxetine, are licensed in the UK for the management of ADHD in school-age children and young people, and are effective in controlling ADHD symptoms [9]. The guidelines produced by the UK...
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