Báo cáo y học: "Molecular imaging of transcriptional regulation during inflammationƠ" docx

... imaging of transcriptional regulation has been applied during inflammation. Introduction Historically conventional imaging techniques as radiog- raphy, computed tomography, ultrasonography and ... in the dairy industry intra-mammary infections are of great economical importance due to loss of milk pro- duction. The dynamics of NF-κB activity was investigated in a mouse mode...

Ngày tải lên: 11/08/2014, 06:22

... Combined imaging of NF-κB activity and protease specific near infrared probe [48]. Evaluation of probe for reactive oxygen species and NF-κB activity in arthritis [49]. Imaging of dietary influence ... pathway regulates GADD45beta expression during acute inflammation. J Biol Chem 2005, 280:21400-21408. 61. Hyoudou K, Nishikawa M, Kobayashi Y, Kuramoto Y, Yamashita F, Hashida...

Ngày tải lên: 11/08/2014, 03:20

... Assistant Professor of Medicine and Staff Physician at the Department of Gastroenterology and Hepatology, University Hospital Freiburg, Germany. Since 2004 he is the head of the Division of Gastroenterology ... understanding of the molecular virology of HCV infection. The investigation of the HCV life cycle and pathogenesis has been complicated by the lack of efficient c...

Ngày tải lên: 02/11/2012, 10:00

... functional studies of the carboxyl-terminal domain Yoko Kobayashi, Toshiaki Nakajima and Ituro Inoue Division of Genetic Diagnosis, Institute of Medical Science, The University of Tokyo, Tokyo, Japan Lipoprotein ... endothelial lipase [1,2]. The primary function of LPL is triglyceride hydrolysis in triglyceride-rich lipoproteins, such as chylomicron and very low density lipoprotein...

Ngày tải lên: 21/02/2014, 15:20

... Wajant 1 1 Institute of Cell Biology and Immunology and 2 Institute of Industrial Genetics, University of Stuttgart, Germany; 3 Institute of Immunology, Christian-Albrechts-University of Kiel, Germany To gain ... 8). Correspondingly, fluorescence of cytoplasmic T4(259–470)– YFP and full-length T4–GFP was already significantly reduced after 2 min of bleaching in a small area of...

Ngày tải lên: 21/02/2014, 15:20

... coordinated way for this sugar to play its diverse functional roles during the life cycle. Consequently, the study of the enzymes involved in trehalose metabolism and the subtle regulation of their activities ... regulated by phosphorylation of the enzyme protein at serine residues [8,9]. Comparatively much less is known about the regulation of the trehalose synthesis in the evo...

Ngày tải lên: 08/03/2014, 23:20

... tetrahydrocolumbamine using this 80% pure tetrahydrocolumbamine. To quantify the enzymatic activity of CoOMT, the transfer of the 3 H-labeled methyl group of S-adenosyl- L - [methyl- 3 H]methionine (0.5 MBqÆlmol )1 )(PerkinElmer Life ... M.H. (1990) S-adenosyl- L -methionine: 3¢-hydroxy-N-methyl-(S) -coclaurine-4¢-O-methyltransferase, a regio- and stereoselective enzyme of the (S)-ret...

Ngày tải lên: 17/03/2014, 10:20

... transcrip- tion by being an auxiliary member of the RNA polymerase II holoenzyme complex. This view is sup- ported by the observation that the function of MRG19 is reminiscent of Gal11p in many respects, ... toxic to wild-type yeast strains that constitutively express galactokinase, due to the accumula- tion of 2-deoxygalactose-1-phosphate [40]. Growth of a wild-type strain bearing...

Ngày tải lên: 31/03/2014, 08:20

... anti-inflammatory effect of methotrexate. During the past 15 years, it has become clear that administration of folic acid in doses of 1–5 mg per day helps to prevent much of the toxicity of methotrex- ate ... that inhibits the synthesis of purines and pyrimidines for the therapy of malignancies, it is now clear that many of the anti- inflammatory effects of methotrexate ar...

Ngày tải lên: 09/08/2014, 03:24

... MG, Kennedy TC, Kempsell KE: Analysis of immune system gene expression in small rheumatoid arthritis biopsies using a combination of subtractive hybridization and high-density cDNA arrays. J Immunol Methods ... Baba H, Nosaka Y, Sugita T, Miyasaka N: Highly expressed dipeptidyl peptidase IV on fibroblast-like synoviocytes as well as activated helper T cells could be a target of RA ther...

Ngày tải lên: 09/08/2014, 06:22