báo cáo khoa học: " Overview of the VA Quality Enhancement Research Initiative (QUERI) and QUERI theme articles: QUERI Series" pptx

... underutilized. In 1998, the U.S. Department of Veterans Affairs' (VA) Quality Enhancement Research Initiative (QUERI) was established to improve the quality of VA healthcare through the use of research- derived ... Access Methodology Overview of the VA Quality Enhancement Research Initiative (QUERI) and QUERI theme articles: QUERI S...

Ngày tải lên: 11/08/2014, 05:22

... underutilized. In 1998, the U.S. Department of Veterans Affairs' (VA) Quality Enhancement Research Initiative (QUERI) was established to improve the quality of VA healthcare through the use of research- derived ... reflections on the potential value of QUERI and its related approaches from the per- spective of both VA (non -QUERI) leadership and...

Ngày tải lên: 11/08/2014, 16:21

... involved in the activation of receptor and non-RTKs, pro-inflammatory signalling, Rho GTPase activation, scattering and motility of gastric epithelial cells, as well as the suppression of histone ... activation (7) and the release of pro-inflammatory cytokines such as IL-8 (8). These cytokines can alter the secretion of mucus and induce changes in gastric acid secretio...

Ngày tải lên: 14/02/2014, 19:20

... polymers of serpins, where the insertion of another molecule’s RCL takes place [8]. Both of these result in the irreversible inactivation (generally) of the serpins, and, in the case of the anticoagulant ... years, involves the attack of the protease on the P1-P1¢ bond in the reactive cen- tre loop (RCL) of the serpin [5]. The catalysis of the peptide...

Ngày tải lên: 20/02/2014, 02:21

... revising the man- uscript and in the design of the study. FS initiated the study and gave major advice for the design of the study and the methods used. All authors read and approved the final manuscript. Acknowledgements The ... stimulations and the design of the study. J-CS participated in the coordination of the study and in gen- erating the...

Ngày tải lên: 13/08/2014, 03:20

... vacuum-assisted closure therapy Vacuum-assisted closure therapy (VAC Vakuumquellen, KCI Therapiegeräte, Höchstadt, Germany) was designed to pro- mote the formation of granulation tissue in the ... suffered at least loss of one rel- ative, for example, a partner or child, and two mothers of our cohort lost both of their children. The majority of patients com- plained of ni...

Ngày tải lên: 25/10/2012, 10:41

... as the ATP-unbound and Ca 2+ -bound E1Ca 2+ form. In the histogram (Fig. 2A) of the dis- tribution of the height of the projection of the embed- ded molecule above the flat membrane surface, the average ... in the range 10 n M to 100 lM. (B, C) Typical distributions of the lifetime of the elevated conformations of SERCA in the presence of 100 l M free...

Ngày tải lên: 14/02/2014, 14:20

... AD families out of 1004) and are only partially penetrant, these results give support to the hypothesis that the human gene for ADAM10 plays a role in the aetiology of AD. ADAM10 and tumour necrosis ... concerning the therapeutic enhancement of ADAM10 a-secretase activity have to be considered. The present review summarizes our knowledge about the structure and funct...

Ngày tải lên: 16/02/2014, 09:20

... activity in the absence of myristoylation, the subcellular localization of the enzyme was altered. Compared with the wild type, the ability of nonmyristoylated JSP1 to induce JNK activation and phosphorylation ... of the transcription factor c-JUN was attenuated. Upon expression of wild-type JSP1, a subpopula- tion of cells, with the highest levels of the phosp...

Ngày tải lên: 16/02/2014, 14:20

... protein, such as control of transcription and mRNA stability, and the relative rate of protein synthesis and degradation. Moreover, the mechanisms by which HSF2 is activated and recruited to its ... increasing the expression of HSF2, it translocates to the nucleus and induces transcription of target genes, suggesting that HSF2 is activated by its elevated concentrati...

Ngày tải lên: 18/02/2014, 04:20