báo cáo khoa học: "A trial platform to develop a tailored theory-based intervention to improve professional practice in the disclosure of a diagnosis of dementia: Study protocol [ISRCTN15871014]" potx

... in the reported practice of disclosure of dementia among healthprofessionals [3]. Four main factors appear to influence disclosure: (1) patient characteristics (e.g. age, ability to retain the ... disclosure of dementia. This work willlead to a randomised controlled trial of the intervention. Aim To develop a tailored theory-based intervention to pro-mote appropriate disclosure of diagnosis of ... design in a manner that simulates a real situa-tion as much as possible. Interim endpoints (statedbehavioural intention and simulation) are measuredrather than changes in professional behaviour...

Báo cáo khoa học: and protein bilinear indices – novel bio-macromolecular descriptors for protein research: I. Predicting protein stability effects of a complete set of alanine substitutions in the Arc repressor ppt

... means of a graphand then calculates the invariants of the associatedmatrices. For example, Randic´and Basak used the principal eigenvalues from matrices as invariants in ananalysis of the ... acid-bilinearindices are calculated by summing the kth amino acidbilinear indices of all amino acids of the same aminoTable 4. Values of nonstochastic and stochastic total bilinear indices for two interacting ... changes in buriedsurface area, with average side-chain B-factors, and with the number of side-chain atoms or total atoms within 6A ˚ of the atoms deleted by the alanine substitution, the pairwise...

Báo cáo khoa học: Etoposide upregulates Bax-enhancing tumour necrosis factor-related apoptosis inducing ligand-mediated apoptosis in the human hepatocellular carcinoma cell line QGY-7703 pdf

... Smac/DIABLO promotes the activation of caspases, such as procaspase-9 and caspase-3,by binding to the inhibitor of apoptosis proteins and thusdisrupts linkage of the caspase–inhibitor of apoptosisproteins ... Nucleic Acid andProtein Analyser (Beckman Coulter). Two micrograms of total RNA was reverse transcribed using the TaKaRa OneStep RNA PCR kit (TaKaRa Bio Inc., Shiga, Japan)according to the manufacturer’s ... eﬀector caspases, such as caspase-3 and -7[55]. The death ligands and the chemotherapeutic agentsare two distinct classes of signals used to induce apoptosisand activate the caspase cascade....

Báo cáo khoa học: "An artificial regeneration system for establishing northern red oak on dry-mesic sites in the Lake States, USA" pptx

... The average stand diameter was 19 cm and the ba-sal area averaged 27.5 m2/ha. The site index fornorthern red oak is 18.6 m (at age 50 yr). The dominant understory ... 1993)Summary — Artificial regeneration of northern red oak is difficult to achieve in the Lake States,USA. A replicated study was established in northern Wisconsin in ... as Rubus.Although we are of the opinion that the re-duced resource availability is the majorfactor in reduced growth, the frost in June,1992 also caused some damage...

báo cáo khoa học: "Best linear unbiased prediction when error vector is correlated with other random vectors in the model" pptx

... constant,Differentiating these equations with respect to 13 and u and equating to 0 gives(3.2). A similar result can be obtained using a Bayesian approach.V. An exampleSuppose that in ... factors in the model are assumed to be zero. This assumption is ordinarilyapplied to most practical applications in the biological sciences when the assumption isinvalid. ... but these are not easy computing algorithms.III. An equivalent modelModels are defined to be equivalent if they yield the same variance-covariancematrix of y, and E(y)...

Báo cáo y học: "Interactions among type I and type II interferon, tumor necrosis factor, and -estradiol in the regulation of immune response-related gene expressions in systemic lupus erythematosus" potx

... Amino allyl RNA (aRNA) was syn-thesized from 1 g total RNA using the Amino Allyl Mes-sageAmp™ aRNA kit (Ambion, Austin, TX, USA). Fivemicrograms of aRNA from each sample (11 SLE patients andsix ... analysis. CA performed labeling and scan-ning of the microarrays. YA assisted with data analysis. NY-Hassisted with data analysis. KM assisted in microarray dataacquirement. NN designed the study, ... human genes. The microarrays were scanned using ScanArray Lite (Perk-inElmer, Boston, MA, USA) and the signal values were calcu-lated using the DNASIS Array (Hitachi Software Engineering,Tokyo,...

Báo cáo y học: " Interactions among type I and type II interferon, tumor necrosis factor, and -estradiol in the regulation of immune response-related gene expressions in systemic lupus erythematosus" pptx

... data analysis, interpreta-tion of the microarray studies, and patient recruitment. HSassisted with data analysis. CA performed labeling and scan-ning of the microarrays. YA assisted with data ... data analysis. NY-Hassisted with data analysis. KM assisted in microarray dataacquirement. NN designed the study, enrolled patients, andassisted with data analysis and interpretation. All authors ... per-formed data analysis, interpretation of the microarray studies,sample preparation, stimulating and co-stimulating experi-ments, RNA purification, quantitative RT-PCR assays, anddrafted of manuscript....

Báo cáo khoa học: " Intensity modulated radiotherapy for localized prostate cancer: rigid compliance to dose-volume constraints as a warranty of acceptable toxicity?" pptx

... its improvement. FRM performed the sta-tistical analysis. ASS and LCM participated in the data col-lection and in radiotherapy planning. All authors readand approved the final manuscript.Acknowledgements The ... anteriorand laterals) were applied to the CTV when defining the planning target volume (PTV).All patients were treated at a Clinac 23-EX® linear acceler-ator (Varian Medical Systems, Palo Alto, ... Adriana S Santos1, Lidiane C Martins1 and Wladmir Nadalin1,2Address: 1Department of Radiation Oncology, Hospital Israelita Albert Einstein, Av. Albert Einstein, 627/701 – Sao Paulo, Brazil,...

báo cáo khoa học: "Uterine and ovarian carcinosarcomas overexpressing Trop-2 are sensitive to hRS7, a humanized anti-Trop-2 antibody" pdf

... (emiliano.cocco@yale.edu)Stefania Bellone (stefania.bellone@yale.edu)Marta Betti (martignaz@hotmail.com)Paola Todeschini (paolat09@yahoo.it)Sara Gasparrini (sara.gasparrini@yale.edu)Elena Ratner (elena.ratner@yale.edu)Dan-Arin ... plasma. This suggests that in the presence of effector PBL, human plasma may augment hRS7-mediated cytotoxicity against carcinosarcomas. Moreover, these results indicate that the binding of ... Health [grant R01 CA122728-0 1A2 to ADS], the Italian Institute of Health [grants 501 /A3 /3, 00227557 to ADS], and the National Cancer Institute at the National Institutes of Health [grant CA16359]....

Tài liệu Báo cáo khoa học: Chromatin under mechanical stress: from single 30 nm ﬁbers to single nucleosomes pdf

... unzipping of the ﬁrst 20 bp of nucleosomalDNA had the same characteristics as those of nakedDNA, indicating a loose interaction of the histoneswith DNA at the entry ⁄ exit points of the NCP. ... is also clearthat the choice of DNA substrate has an impact on the results [57]. The question of the effect of the linkerhistone association still remains an open issue as most of the array ... explanations is the association of non-histone proteins (e.g. HMGproteins) with chromatin, leading to an additional sta-bilization, mainly of the outer turn. The study of Popeand colleagues...

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