... Parameters in Allergy, Asthma, and Immunology defined rhinitis as‘‘inflammation of the membrane lining the nose, character-ized by nasal congestion, rhinorrhea, sneezing, itching of the nose and/or ... newer-generationINCs become available, they, too, will need to meet orexceed the safety standards set by the currently availabletherapies for AR. Understanding the potential concernsand the data behind these ... pharmacotherapy, and immunotherapy.4Pharmacotherapy options for AR include antihista-mines (oral and intranasal), oral leukotriene receptorantagonists, and INCs. Treatment guidelines for...