Báo cáo y học: "Riding the knowledge translation roundabout: lessons learned from the Canadian Institutes of Health Research Summer Institute in knowledge translation" doc

... Science Open Access Meeting report Riding the knowledge translation roundabout: lessons learned from the Canadian Institutes of Health Research Summer Institute in knowledge translation Michelle ... Corresponding author Abstract Background: Funding the education and training of the next generation of health researchers is a key mandate of the...

Ngày tải lên: 11/08/2014, 05:21

... training of the next generation of health researchers is a key mandate of the Canadian Institutes of Health Research (CIHR) knowledge translation (KT) portfolio. The field of KT is growing daily; ... knowledge translation roundabout: lessons learned from the Canadian Institutes of Health Research Summer Institute in knowledge tran...

Ngày tải lên: 11/08/2014, 16:20

... to some extent. Only about one-fourth of low-density lipo- proteins in the body are associated with diet and the remainder is produced by the liver or other cells in the body [1]. The two major strategies ... the benefits associated with the other conditions, the most likely scenario associated with eating an egg a day is savings of $2.82 billion annually with uncertai...

Ngày tải lên: 13/08/2014, 11:22

... avidity for the index sequence epitope. Interestingly, we also fo und four examples of increases in response avidity over the first year of infection. Two of these occurred in associa- tion with intra-epitopic ... than initially subdominant responses of lower avidity [32,33]. Further, we assessed changes in response avidity over only the first year of infecti on: the l...

Ngày tải lên: 13/08/2014, 01:20

... registers. Ethical approval The study received an approval from the Uganda Ministry of Health and the offices of the district directors of health services in all the three districts. The methodology was also ... administrative point designated for meetings in the camp as identified by the camp commandant whereas in the case of health facility the coor...

Ngày tải lên: 13/08/2014, 13:21

... eIF2B activity under any of the stress conditions tested here (data not shown), seemingly ruling out a role for this protein in the inhibitory effects of all three stresses on protein synthesis in these ... recycling of eIF2 to this form [29,30]. The activity of eIF2B can be modulated in a variety of ways [29,31] including by its own phosphoryla- tion, and through phosph...

Ngày tải lên: 18/03/2014, 01:20

... that bind to the SH2 domains. The tandem SH2 domains bind to Tyr-627 and Tyr-659 simultaneously in a specific orientation, in which Tyr-627 binds to the N-SH2 domain and Tyr-659 binds to the ... previously that G/G of the PTPN11 gene encoding SHP-2 increased the risk of gastric atrophy among the seropositive subjects [18]. The present study examined the associat...

Ngày tải lên: 31/10/2012, 15:37

... As both the E a of inactivation and the temperature at which the enzyme starts inactivating at a measurable rate increase from the apoenzyme to the Mn 2þ -containing enzyme, loss of the metal cofactor ... between the buffer and the enzyme by preincubating the enzyme–metal mixture at 30 8C for 30 min. Remaining activity was measured with glucose as the substrate in...

Ngày tải lên: 22/02/2014, 07:20

... only partially soluble in five of the constructs resulting in very poor yields. Intriguingly, in the sixth con- struct, the yield of soluble fusion protein with an extended carboxyl terminus of ... solubility of fusion proteins is not necessarily indicative of either proper folding or of increased solubility of the protein of interest. We propose that the succes...

Ngày tải lên: 23/03/2014, 21:20

... between the CaM-binding domain and the CnB- binding helix and increases the affinity of the CaM-binding domain for Ca 2+ /CaM [25,26]. The regulation of the CaM- binding domain by CnB may partly account ... Ca 2+ - binding to the low affinity sites, the CaM-binding domain interacts with the exposed side of the CnB-binding helix [26]. Calcium binding to the low affinit...

Ngày tải lên: 24/03/2014, 03:21