Báo cáo y học: " Learning from the U S Department of Veterans Affairs Quality Enhancement Research Initiative: QUERI Series Ian D Graham* and Jacqueline Tetroe" potx

... describing successes and challenges as well as setbacks and disappointments, the QUERI Series is all the more useful. From the vantage point of Canadian KT researchers and officials at a national health research funding ... for the problems those in the health system identify and prioritize. And this responsive research should be adequately funded. There also i...

Ngày tải lên: 11/08/2014, 05:21

... Analysis Results are expressed as the mean ± standard error (S. E.), and statistical comparisons were based on unpaired Student s t test. A p-value of less than 0.05 was considered as statistically ... thousands of years and renowned for its therapeutic effects on gynecological disorders, such as amenorrhea and menopause [5]. Recent pharmacological studies demonstrated th...

Ngày tải lên: 02/11/2012, 10:19

... spectrometric analyses. Although anomalous migration of the b subunit was observed by standard SDS/PAGE analysis, which indicated the presence of two bands (as previously observed for other OATs), mass spectrometric ... Previously it has been repor- ted that the b subunit of OATs from thermophiles run anomalously by SDS/PAGE analysis [25] and the b subunit of OAT from ye...

Ngày tải lên: 08/03/2014, 22:20

... coefficients w ere reduced to s 20, w by standard procedures. Analysis of the state of association The state of association was analysed by size- exclusion chromatography experiments at 20 °C on a Superose ... was c onfirmed by MS analysis. The automated Edman degradation o f the native protein was unsuccessful for the possible p resence o f a blocked N-terminus. MALDI-TOF MS...

Ngày tải lên: 08/03/2014, 23:20

... agreement with the simultaneous presence of 2-substituted and 2,6- disubstituted Man shown by methylation analysis. Consid- ering the linkage position of b-Gal residues found in the other compounds and the ... studied. endoH-released species comprised terminal, 2-substituted and 3,6-disubstituted mannosyl residues as well as small amounts of terminal Gal and 4- or 3-subs...

Ngày tải lên: 31/03/2014, 08:20

... values at day 14. The data were analyzed using SAS software (SAS Institute, Cary, NC, USA). The Student&apos ;s t-test was used in the Westen blot analysis, and P < 0.05 was considered statistically ... from four healthy individuals, designated the standard. The blots were quantified by densitometric analysis and the ratio of RA patient/standard was calculated. Blots...

Ngày tải lên: 09/08/2014, 08:23

... secretion of cytokines and growth factors by infiltrating cells and resident synovial cells. This leads to increased production of ADAMTSs and MMPs by synovial fibroblasts and by chondrocytes, favouring ... metalloproteinases (MMPs) [16]. Metalloproteinases This group of proteases is divided into five families: the serralysins, the astacins, the adamalysins, the MMPs an...

Ngày tải lên: 09/08/2014, 10:21

... because they are surrogates for the cumulative disease activity and disease severity. Those patients whose disease starts badly tend to continue to do badly. We have shown the benefits of starting disease-modifying ... dataset has been used to address questions about the occurrence of a variety of outcomes at 1 year, 3 years, 5 years and now 10 years, as well as predictors of...

Ngày tải lên: 09/08/2014, 08:22

... considering tissue histology [4] and estimation of the mechanical property of meniscus [6], was studied aiming toward human clinical study [7]. Our ultra- sound system can be used with the arthroscopic ... Young modulus, indicating the speed of sound, the density of a material, and the acoustic impedance of a material [4], and presented the Gabor function as the...

Ngày tải lên: 09/08/2014, 14:21

... arthritis (RA). No single animal model of arthritis truly represents the human disease, but the models mimic various aspects and can be used as tools to understand particular pathways. Developments ... over the past decade include the generation of novel models as well as pathway analysis and therapeutic targeting in classic models. Aspects peculiar to individual models are o...

Ngày tải lên: 09/08/2014, 14:22