Bone Regeneration and Repair - part 10 potx
... PDGF-BB-loaded CS-chitosan sponge may factor-BB from chondroitin sulfate-chitosan dissected from 21-d-old Sprague-Dawley rat potentially control PDGF-BB release. Incorporated sponge for guided bone ... factor-β Individual growth factors IGF-1, PDGF, and TGF-β determine what effect, if any, decalcified (TGF-β), insulin-like growth factor-1 all showed a noticeable effect and a significant...
Ngày tải lên: 11/08/2014, 05:20
... lineage (re- viewed in ref. 102 ). ILs (1,6, and 11), PTH, PTHrP, TNF, prostaglandins, annexin-II, TGF-β, M-CSF, and RANK ligand stimulate osteoclast formation (13,97,98). M-CSF and RANK ligand are ... by primitive mesenchymal proteins (BMP-2, and IGF-II expression (69) and osteoprogenitor cells, fibroblasts, BMP-4, BMP-7) –BMP-2 increases TGF-β and IL-6 and proliferating chond...
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... suggest that BMP-2, -4 , and -7 work to promote fracture healing and bone regeneration (81). Osteonectin is one of many extracellular matrix proteins involved with bone repair and regenera- tion. In ... (1992) Insulin-like growth factor-I supports formation and activation of osteoclasts. Endocrinol- ogy 131(3), 107 5 108 0. 61. Beck, F., et al. (1987) Histochemical loca...
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Bone Regeneration and Repair - part 3 doc
... factor and cytokine receptors bFGFR, PDGFR, IL-1R, IL-3R, IL-4R, IL-6R, IL-7R, IFN-γR, EGFR-3, IL-2R TNFIR and TNFIIR, TGFβIR and TGFβIIR Cell adhesion molecules ICAM-1 and -2 , VCAM-1, L-selectin, ... LFA-3, ALCAM ICAM-3, cadherin-5, E-selectin, P-selectin, PECAM-1 Miscellaneous antigens Transferrin receptor, CD9, Thy-1, SH-2, SH-3, SH-4, SB-20, SB-21 CD4, CD14, CD34, CD45, von Wi...
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Bone Regeneration and Repair - part 4 ppt
... role in bone regeneration and remodeling, a group has begun experimenting with platelet-rich plasma (PRP) and platelet-poor plasma (PPP), both rich in PDGF, TGF-α, and TGF-β, as possible bone graft ... version www.adultpdf.com 142 Sutherland and Bostrom polyglycolide (PGA) and poly-L-lactide (PLLA), which allow for new bone growth and therefore do not degrade like PMMA (10...
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Bone Regeneration and Repair - part 5 ppt
... elegans. All TGF-βs are disulfide-linked dimers comprising 12–18 kDa subunits (55). Most are homodimers (TGF-βl, TGF-β2, and TGF-β3), but some are heterodimers (TGF-β1.2 and TGF-β2.3) (56). TGF-βs are ... growth factor-2 (0.1 mL)-treated (E–H) fibulae. The radiographs were obtained immediately after surgery (A and E) and 3 (B and F), 5 (C and G), or 10 (D and H) wk following s...
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Bone Regeneration and Repair - part 6 pot
... experimental long -bone defect. J. Bone Joint Surg. 43A, 1261. 173. Thaller, S. R., Hoyt, J., Tesluk, H., and Holmes, R. (1993) Effect of insulin-like growth factor-1 on zygomatic arch bone regeneration: ... 195 195 From: Bone Regeneration and Repair: Biology and Clinical Applications Edited by: J. R. Lieberman and G. E. Friedlaender © Humana Press Inc., Totowa, NJ 11 The I...
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Bone Regeneration and Repair - part 7 pot
... particles should be between 7 and 10 mm, which is notable because most standard bone mills yield graft particles between 2 and 5 mm in size (13–15). The biology of bone graft incorporation (10, 11,14–19) ... maximum host bone- to-cup contact, and the large cup is used to span bone defects. Jasty (64) reviewed 19 hips treated with a jumbo cup and particulate allograft bone a...
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Bone Regeneration and Repair - part 8 pot
... results at a mean 1 0- yr follow-up of 60 recon- structions (48 type III, and 12 type IV) using bulk allograft bone and the Kerboull acetabular rein- forcement device. This cruciate-shaped device ... increase IGF-II in TE-85 human bone cell cultures. Endocrinology 136, 3100 – 3106 . 23. Fitzsimmons, R. J., Ryaby, J. T., Magee, F. P., and Baylink, D. J. (1995) IGF-II receptor number...
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Bone Regeneration and Repair - part 9 docx
... situ and subse- quently harden at the osseous site in 15–20 min (106 ). Alpha-BSM can slowly biodegrade and become replaced with bone (107 ). Physiological mechanisms for CPCs relevant to bone regeneration ... osteoblast-like phenotypes and angiogen- esis (120), suggesting a strong involvement in bone formation, fracture repair, and bone regeneration. Moreover, FGF-2 has...
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