Bone Regeneration and Repair - part 10 potx
Bone Regeneration and Repair - part 10 potx
... PDGF-BB-loaded CS-chitosan sponge may
factor-BB from chondroitin sulfate-chitosan dissected from 21-d-old Sprague-Dawley rat potentially control PDGF-BB release. Incorporated
sponge for guided bone ... factor-β Individual growth factors IGF-1, PDGF, and TGF-β
determine what effect, if any, decalcified (TGF-β), insulin-like growth factor-1 all showed a noticeable effect and a significant...
Bone Regeneration and Repair - part 1 ppt
... lineage (re-
viewed in ref. 102 ). ILs (1,6, and 11), PTH, PTHrP, TNF, prostaglandins, annexin-II, TGF-β, M-CSF,
and RANK ligand stimulate osteoclast formation (13,97,98). M-CSF and RANK ligand are ... by primitive mesenchymal
proteins (BMP-2, and IGF-II expression (69) and osteoprogenitor cells, fibroblasts,
BMP-4, BMP-7) –BMP-2 increases TGF-β and IL-6 and proliferating chond...
Bone Regeneration and Repair - part 2 pdf
... suggest that BMP-2, -4 , and -7 work to promote
fracture healing and bone regeneration (81).
Osteonectin is one of many extracellular matrix proteins involved with bone repair and regenera-
tion. In ... (1992) Insulin-like growth factor-I supports formation and activation of osteoclasts. Endocrinol-
ogy 131(3), 107 5 108 0.
61. Beck, F., et al. (1987) Histochemical loca...
Bone Regeneration and Repair - part 3 doc
... factor and cytokine receptors
bFGFR, PDGFR, IL-1R, IL-3R, IL-4R, IL-6R, IL-7R, IFN-γR, EGFR-3, IL-2R
TNFIR and TNFIIR, TGFβIR and TGFβIIR
Cell adhesion molecules
ICAM-1 and -2 , VCAM-1, L-selectin, ... LFA-3, ALCAM ICAM-3, cadherin-5, E-selectin,
P-selectin, PECAM-1
Miscellaneous antigens
Transferrin receptor, CD9, Thy-1, SH-2, SH-3, SH-4, SB-20, SB-21 CD4, CD14, CD34, CD45,
von Wi...
Bone Regeneration and Repair - part 4 ppt
... role in bone regeneration and remodeling, a group has
begun experimenting with platelet-rich plasma (PRP) and platelet-poor plasma (PPP), both rich in
PDGF, TGF-α, and TGF-β, as possible bone graft ... version
www.adultpdf.com
142 Sutherland and Bostrom
polyglycolide (PGA) and poly-L-lactide (PLLA), which allow for new bone growth and therefore do
not degrade like PMMA (10...
Bone Regeneration and Repair - part 5 ppt
... elegans.
All TGF-βs are disulfide-linked dimers comprising 12–18 kDa subunits (55). Most are homodimers
(TGF-βl, TGF-β2, and TGF-β3), but some are heterodimers (TGF-β1.2 and TGF-β2.3) (56). TGF-βs
are ... growth
factor-2 (0.1 mL)-treated (E–H) fibulae. The radiographs were obtained immediately after surgery (A and E)
and 3 (B and F), 5 (C and G), or 10 (D and H) wk following s...
Bone Regeneration and Repair - part 6 pot
... experimental long -bone defect.
J. Bone Joint Surg. 43A, 1261.
173. Thaller, S. R., Hoyt, J., Tesluk, H., and Holmes, R. (1993) Effect of insulin-like growth factor-1 on zygomatic arch
bone regeneration: ... 195
195
From: Bone Regeneration and Repair: Biology and Clinical Applications
Edited by: J. R. Lieberman and G. E. Friedlaender © Humana Press Inc., Totowa, NJ
11
The I...
Bone Regeneration and Repair - part 7 pot
... particles should be between 7 and 10
mm, which is notable because most standard bone mills yield graft particles between 2 and 5 mm in
size (13–15).
The biology of bone graft incorporation (10, 11,14–19) ... maximum host bone- to-cup contact, and
the large cup is used to span bone defects. Jasty (64) reviewed 19 hips treated with a jumbo cup and
particulate allograft bone a...
Bone Regeneration and Repair - part 8 pot
... results at a mean 1 0- yr follow-up of 60 recon-
structions (48 type III, and 12 type IV) using bulk allograft bone and the Kerboull acetabular rein-
forcement device. This cruciate-shaped device ... increase
IGF-II in TE-85 human bone cell cultures. Endocrinology 136, 3100 – 3106 .
23. Fitzsimmons, R. J., Ryaby, J. T., Magee, F. P., and Baylink, D. J. (1995) IGF-II receptor number...
Bone Regeneration and Repair - part 9 docx
... situ and subse-
quently harden at the osseous site in 15–20 min (106 ). Alpha-BSM can slowly biodegrade and become
replaced with bone (107 ).
Physiological mechanisms for CPCs relevant to bone regeneration ... osteoblast-like phenotypes and angiogen-
esis (120), suggesting a strong involvement in bone formation, fracture repair, and bone regeneration.
Moreover, FGF-2 has...
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