Bone Regeneration and Repair - part 8 pot
Bone Regeneration and Repair - part 8 pot
... External,
Electrodes/ Non-invasive Non-invasive Non-invasive
Battery, Invasive
Percent Change 27 18 20 21
Active 81 83 85 64
Placebo 54* 65 65 43
Clinical Trial Randomized, Double-blind, Double-blind, Double-blind,
*not ... that bone grafts
(autograft and allograft) can be used successfully in some cases for reconstruction after deep infec-
tion (6 ,8, 9 ,84 ,87 ,88 ).
This is trial v...
Bone Regeneration and Repair - part 6 pot
... binding proteins in serum and other bio-
logical fluids: regulation and functions. Endocr. Res. 18, 80 1 83 1.
160. Copeland, K. C., Underwood, L. E., and Van Wyk, J. J. (1 980 ) Induction of immunoreactive ... T., and Froesch, E. R. (1 984 ) IGF-1 supports differentiation of cultured osteoblast-like cells. FEBS
Lett. 173, 48 52.
1 68. Canalis, E. and Lian, J. B. (1 988 ) Effects o...
Bone Regeneration and Repair - part 7 pot
... Trans. 18, 88 6 88 7.
67. Lowery, G. L., Maxwell, K. M., Karasick, D., Block, J. E., and Russo, R. (1995) Comparison of autograft and compos-
ite grafts of demineralized bone matrix and autologous bone ... allografts in rabbits. J. Bone Joint Surg. 58A, 85 4 85 8.
61. Friedlaender, G. E., Strong, D. M., and Sell, K. W. (1 984 ) Studies on the antigencity of bone. I. Donor-spe...
Bone Regeneration and Repair - part 10 potx
... PDGF-BB-loaded CS-chitosan sponge may
factor-BB from chondroitin sulfate-chitosan dissected from 21-d-old Sprague-Dawley rat potentially control PDGF-BB release. Incorporated
sponge for guided bone ... Testing the hypotheses.
Trends Genet. 7, 411–4 18.
57. Soriano, P. (1994) Abnormal kidney development and hematological disorders in PDGF beta-receptor mutant mice.
Genes Dev. 8, 188 8– 1...
Bone Regeneration and Repair - part 1 ppt
... lineage (re-
viewed in ref. 102). ILs (1,6, and 11), PTH, PTHrP, TNF, prostaglandins, annexin-II, TGF-β, M-CSF,
and RANK ligand stimulate osteoclast formation (13,97, 98) . M-CSF and RANK ligand are ... mesenchymal
proteins (BMP-2, and IGF-II expression (69) and osteoprogenitor cells, fibroblasts,
BMP-4, BMP-7) –BMP-2 increases TGF-β and IL-6 and proliferating chondrocytes (66–...
Bone Regeneration and Repair - part 2 pdf
... protein-1 (OP-1;BMP-7) and transforming growth factor-beta 1 on
bone formation in vitro. Connect. Tissue Res. 35(1–4), 71– 78.
45. Pfeilschifter, J., Seyedin, S. M., and Mundy, G. R. (1 988 ) Transforming ... Bull. 55(4), 85 6 86 9.
9. Nemeth, G. G., Bolander, M. E., and Martin, G. R. (1 988 ) Growth factors and their role in wound and fracture heal-
ing. Prog. Clin. Biol. Res....
Bone Regeneration and Repair - part 3 doc
... factor and cytokine receptors
bFGFR, PDGFR, IL-1R, IL-3R, IL-4R, IL-6R, IL-7R, IFN-γR, EGFR-3, IL-2R
TNFIR and TNFIIR, TGFβIR and TGFβIIR
Cell adhesion molecules
ICAM-1 and -2 , VCAM-1, L-selectin, ... LFA-3, ALCAM ICAM-3, cadherin-5, E-selectin,
P-selectin, PECAM-1
Miscellaneous antigens
Transferrin receptor, CD9, Thy-1, SH-2, SH-3, SH-4, SB-20, SB-21 CD4, CD14, CD34, CD45,
von Wi...
Bone Regeneration and Repair - part 4 ppt
... Frequency, treatment, and
end-results. J. Bone Joint Surg. 72, 82 5 83 3.
8. Bland, Y. S., Critchlow, M. A., and Ashhurst, D. E. (1995) Exogenous fibroblast growth factors-1 and -2 do not
accelerate ... role in bone regeneration and remodeling, a group has
begun experimenting with platelet-rich plasma (PRP) and platelet-poor plasma (PPP), both rich in
PDGF, TGF-α, and T...
Bone Regeneration and Repair - part 5 ppt
... elegans.
All TGF-βs are disulfide-linked dimers comprising 12– 18 kDa subunits (55). Most are homodimers
(TGF-βl, TGF-β2, and TGF-β3), but some are heterodimers (TGF-β1.2 and TGF-β2.3) (56). TGF-βs
are ... of OP-1 bone morphogenetic pro-
tein (BMP-7) in a human fibular defect. J. Bone Joint Surg. 81 (4), 710–7 18.
48. Gerhart, T., Kirker-Head, C., Kriz, M., et al. (1991) Healing o...
Bone Regeneration and Repair - part 9 docx
... osteoblast-like phenotypes and angiogen-
esis (120), suggesting a strong involvement in bone formation, fracture repair, and bone regeneration.
Moreover, FGF-2 has a potent influence on bone formation (121–124), ... precursor cell and BMP binding the receptor. Subsequent stimu-
lus of Smad 1, -5 , -8 , interactions with Smad-4, and transport across the nuclear membrane....