Báo cáo y học: " Effects of pro-inflammatory cytokines on expression of kynurenine pathway enzymes in human dermal fibroblasts" pdf
Báo cáo y học: " Effects of pro-inflammatory cytokines on expression of kynurenine pathway enzymes in human dermal fibroblasts" pdf
... studies of disease-related abnormalities in the kynurenine pathway of tryptophan degradation. Keywords: human, fibroblast, kynurenine pathway, gene expression, cytokine Introduction The kynurenine pathway ... 8:25 http://www.journal-inflammation.com/content/8/1/25 Page 7 of 7 RESEARCH Open Access Effects of pro-inflammatory cytokines on expression of kynure...
Ngày tải lên: 11/08/2014, 03:20
Báo cáo y học: "Effects of pro-inflammatory cytokines on expression of kynurenine pathway enzymes in human dermal fibroblasts" pot
... abnormalities in the kynurenine pathway of tryptophan degradation. Keywords: human, fibroblast, kynurenine pathway, gene expression, cytokine Introduction The kynurenine pathway (KP) is the main route of ... Access Effects of pro-inflammatory cytokines on expression of kynurenine pathway enzymes in human dermal fibroblasts Linnéa Asp 1 , Anne-Sofie...
Ngày tải lên: 11/08/2014, 06:23
Tài liệu Báo cáo Y học: Purification, characterization, cloning, and expression of the chicken liver ecto-ATP-diphosphohydrolase pot
... hydrolysis by 70% whereas ATP hydrolysis was inhibited by only 10%. Inhibition of ADP and ATP hydrolysis by azide was greater when the pH of assay solutions was 6.4. Azide inhibition was diminished if ... chromatogra- phy buffer, buffer containing 0.5 M NaCl, and buffer again. The enzyme was eluted with 50 m M glycine, pH 2.5 containing 0.1% NP-40. Fractions of 1 mL were collected int...
Ngày tải lên: 22/02/2014, 04:20
Báo cáo y học: "Differential Constitutive and Cytokine-Modulated Expression of Human Toll-like Receptors in Primary Neutrophils, Monocytes, and Macrophages" docx
... the effects of im- mune-modulating cytokines on protein expression but focused on the effects on TLR mRNA expression. Pro- inflammatory cytokines may also control protein ex- pression of TLRs on ... anti-bacterial innate immunity surveillance. Alterna- tively, they suggest that separate expression control of TLR5 by inflammatory cytokines may contribute to reg...
Ngày tải lên: 08/08/2014, 16:23
Báo cáo y học: "Octacalcium phosphate crystals directly stimulate expression of inducible nitric oxide synthase through p38 and JNK mitogen-activated protein kinases in articular chondrocytes" pps
... IL-1β. Inhibition of iNOS by actinomycin and cycloheximide may reflect, at least in part, inhibition of AP-1 complex synthesis, normally induced by BCP crystals. Conclusion In summary, this study ... and one is inducible (iNOS or NOS-2). Expression of iNOS has been demonstrated in various cell types. Within the joint, chondrocytes may be the main cell source of NO, and iNOS e...
Ngày tải lên: 09/08/2014, 06:23
Báo cáo y học: "Early Differential signaling mechanisms regulate expression of CC chemokine receptor-2 during monocyte maturatio" ppsx
... tissues. PMA-treatment of monocytes induces selective downregulation of CCR2 Based on the above results we decided to further examine the regulation of CCR2 expression in monocyte matura- tion using the human monocyte ... granularity of the cells. In addi- tion, we demonstrated an up-regulation in expression of genes associated with monocyte differentiation, notably C...
Ngày tải lên: 11/08/2014, 08:21
Báo cáo y học: "Coccidioides posadasii infection alters the expression of pulmonary surfactant proteins (SP)-A and SP-D" pps
... The metabolic pathways of pulmonary type II epithelial cells may be affected by secondary inflammatory mediators, such as TNF-α or IL-1β, secreted by inflammatory cells during C. posadasii infection. A ... individuals against Coccidioides [5,6]. However, information is lacking regard- ing the pulmonary innate immune components that may play a critical role in regulation of immune respon...
Ngày tải lên: 12/08/2014, 18:21
Báo cáo y học: "Cerebellum-specific and age-dependent expression of an endogenous retrovirus with intact coding potential" pdf
... strand (46 conversion positions vs. 23 no conversion positions) and minus strand (75 conversion positions vs. 63 no conversion positions). In addition, the average number of converted cytosine 22 the ... brain stem, hippocampus, and olfactory bulb). In particular, significant difference in the frequency of cytosine to thymine conversion (red half-circle) or in the frequency...
Ngày tải lên: 13/08/2014, 01:21
Báo cáo y học: "Occurrence and adverse effect on outcome of hyperlactatemia in the critically ill" pptx
... effect of hyperlactatemia on mortality. Materials and methods Study population The patients included in the study were from a regional health care system including the city of Calgary and surrounding smaller ... hours of ICU admission were considered to not exhibit hyperlactatemia. Severity of illness at inception (within the first day of ICU admission) was assessed using the Ac...
Ngày tải lên: 13/08/2014, 16:21
Báo cáo y học: "Innate immunity triggers IL-32 expression by fibroblast-like synoviocytes in rheumatoid arthritis" ppsx
... TNF-α resulted in a strong induction of IL-32 mRNA expression as compared with stimulation with only one of these cytokines. This synergistic effect was observed in IL-32 mRNA 4 h and 24 h after activation ... amplification of inflammatory reactions in RA, by expressing IL-32, which in turn induces the expression of TNF-α, IL-1, or IL-18 by macrophages or dendritic cells,...
Ngày tải lên: 12/08/2014, 14:22