Báo cáo y học: "Activation of monocytes and cytokine production in patients with peripheral atherosclerosis obliterans" docx

... of 7Plasma levels of pro and anti-inflammatory cytokinesPlasma levels of IL-6, TNF-a and IFN-g were significantlyhigher in patients; t he levels of the anti-infl ammatorycytokines IL-10 and ... expression of adhesion molecules of the endothelium and synthesis of other pro-inflammatorycytokines such as IL-1 and IL-6.Similar to results regarding pro-inflammatory cytokines,high levels of anti-inflammatory ... 8:23http://www.journal-inflammation.com/content/8/1/23Page 6 of 7 in peripheral blood, t he objectives of the present studywere to evaluate the plasma levels of anti-inflammatory and inflammatory cytokines including interleukin-6 (IL-6),...

Báo cáo y học: "Activation of WNT and BMP signaling in adult human articular cartilage following mechanical injury" potx

... show modulation of the BMP and WNT pathways following mechanical injury in vitro and in vivo,which may play a role in the reparative response of the jointsurface. These pathways may, therefore, ... (h) Haematoxylin-eosin and (i) safranin O stainings of an explant with a relatively high degree of osteoarthritis (modified Mankin score 5). (j-m) Immunos-taining for β catenin in parallel, ... independently of the expression of one ligand,including secretion and solubility of the ligand(s), its/their bind-ing to matrix molecules, the presence of secreted or intracellu-lar inhibitors and...

Báo cáo y học: " Effects of cyclophosphamide on pulmonary function in patients with scleroderma and interstitial lung disease: a systematic review and meta-analysis of randomized controlled trials and observational prospective cohort studies" ppt

... effectiveness of CYC therapy in preventing adecline in lung function and premature death in patients with SSc and ILD.Despite these individual study results, previous systematicreviews of retrospective ... of the patients were treated with intrave-nous CYC [12]. We analyzed the two cohorts of patients in this study separately. In addition, in this study the FVC and theDLCO were assessed in both ... with disease-modify-ing drugs (D-penicillamine, cyclosporine, and combination of Table 3Observational study characteristicsStudy Number of patients Mean age (years) Outcome measureaCYC...

Báo cáo y học: "Effect of adalimumab on neutrophil function in patients with rheumatoid arthritis" pps

... aim of the study was to determine whetherdownregulation of phagocyte activities are involved in theanti-inflammatory activity of anti-TNF-α therapy. The lack of activity on phagocytosis, ROS production ... N-formyl-1-methionyl-l-leucyl-1-phenylalanine: analysis of single cellmovement. J Leukocyte Biol 1992, 52:630-636.27. Binder R, Kress A, Kan G, Herrmann K, Kirschfink M: Neutrophilpriming by cytokines and ... in part, that down-regulation of phagocyte activity may be involved in themechanism of action of anti-TNF-α therapy [9].BSA = bovine serum albumin; C3Zy = C3-coated zymosan; FMLP = N-formyl-methionyl-leucyl-phenylalanine;...

Báo cáo khoa học: " Quality of life and salivary output in patients with head-and-neck cancer five years after radiotherapy" pptx

... study and revised the manuscript critically. WB madethe analysis and interpretation of the data, and has beeninvolved in drafting the manuscript. CT participated in the design of the study, ... definition forobjective parotid gland toxicity [24]. The number of thisgroup of patients diminished in time, constituting almostone-fifth of the total at 5 years. The number of patients with ... included in the study. Otherinclusion criteria were no previous RT or surgery of theparotid glands, no history of suffering from malignanciesor other diseases of the parotid glands and WHO 0–1.Patients...

Báo cáo y học: " Management of HIV-1 associated hepatitis in patients with acquired immunodeficiency syndrome: role of a successful control of viral replication" ppsx

... occurrence of opportunistic infections and can-cers. Abnormal liver enzymes (aspartate aminotransfer-ase, AST and alanine aminotransferase, ALT) arefrequently seen in HIV-1 infected patients and may ... malities, clearly referred tothe use of specific antiretroviral drugs (hyperbilirubine-mia and gamma-glutamil-transpeptidase mild increases with indinavir and nevirapine, respectively). HBV and HCV ... onset of lipodistrophy signs, and on July2009 he returned t o our clinic, showing a worsening of clinical conditions (fever, weight loss, night sweats, and oropharyngeal candidiasis). Laboratory...

Báo cáo y học: " Effects of asenapine on depressive symptoms in patients with bipolar I disorder experiencing acute manic or mixed " pot

... events and withdrawn consent with asenapine, lack of efficacy and withdrawn consent with placebo, and lack of efficacy with olanzapine (Table 1).EfficacyMontgomery-Asberg Depression Rating Scale ... oversight of the trials, theanalysis and interpretation of these post hoc analyses, and in thepreparation and finalization of the manuscript. AvW and KN were involved in the analysis and interpretation ... involved in the oversight of the trials, the analysis and interpretation of these post hoc analyses, and in the preparation and finalization of themanuscript. JP was involved in the design and...

Báo cáo y học: " CCR5Δ32 variant and cardiovascular disease in patients with rheumatoid arthritis: a cohort study" ppsx

... participated in the design of thestudy and the data analysis, and helped to draft the manuscript RPMparticipated in genotypin g and data analysis. TRV, JAMF and LR participated in the acquisition and interpretation ... Kalina A, Szabó T, Nagy B, Horváth L,Császár A: Involvement of polymorphisms in the chemokine system in the susceptibility for coronary artery disease (CAD): coincidence of elevated Lp(a) and ... EthicsCommittee of Galicia (Spain) and the Hospital ClinicoSan Carlos (Madrid).GenotypingCCR5 genotypingDNA from patients was obtained from whole peripheral blood using standard methods....

Báo cáo y học: " Cervicocephalic kinesthetic sensibility and postural balance in patients with nontraumatic chronic neck pain – a pilot study" pps

... study of patients with complaints of continuous neckpain during the 3 months prior to recruitment. Thirteen patients with chronic neck pain of nontraumaticorigin were recruited from an institutional ... [Microsoft, Seattle, WA]), and rawtraces were produced both numerically and graphically.Accompanying software (Finsole Orthothic AnalyzingSuite, HUR, Balance Software 1.23, Tampere, Finland)provided ... Council (board of ethical approval), in accord-ance with the Declaration of Helsinki. Patients complaining of 3 months of ongoing neck pain(13 women and 2 men, mean age = 38.8 years; SD = 7.4)were...

Báo cáo y học: " Pulse-pressure variation and hemodynamic response in patients with elevated pulmonary artery pressure: a clinical study" ppt

... challenges, resulting in increased SV, and in 44% of those in which SV did not increase (P = 0.0003). EDV increased in 28% of fluid challenges, resulting in increased SV, and in 44% of those in which ... prediction of volume responsiveness with PPV in patients with increased pulmonary artery pressure.Methods: Fifteen cardiac surgery patients with a history of increased pulmonary artery pressure ... theCanton of Bern. Written informed consent was obtainedfrom 20 cardiac surgery patients with a preoperative his-tory of increased pulmonary artery pressure, and fromboth an independent physician and...

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