Báo cáo y học: "Controlled meal frequency without caloric restriction alters peripheral blood mononuclear cell cytokine production" potx

... regulatory T cells. Proc Natl Acad Sci USA 2005, 102:5150-5155. doi:10.1186/1476-9255-8-6 Cite this article as: Dixit et al.: Controlled meal frequency without caloric restriction alters peripheral blood ... previously reported on a human meal fre- que ncy study in which the daily calories were held con- stant between two diets that differed only in meal frequency (3 sma...

Ngày tải lên: 11/08/2014, 03:20

... sclerosis; PCR = polymerase chain reaction; PBMC = peripheral blood mononuclear cell; RA = rheumatoid arthritis; SDA = Symbolic discriminant analysis; SLE = systemic lupus erythematosus; SLEDAI ... clinically relevant changes in gene expression should be observed in peripheral blood mononuclear cells (PBMCs). Using peripheral blood as the source of gene expression material of...

Ngày tải lên: 09/08/2014, 01:23

... identified by homology searches [3]. Two types of PRMTs have been subclassified based on the symmetry of their reaction products. Using Keywords cytokines; inhibitors; nuclear factor of activated T cells ... of dimethylsulfoxide, MTA, AMI-1, or compound 4. Cellular proliferation was determined using the MTS [3-(4,5- dimethylthiazol-2-yl)-5-(3-carboxymethoxy- phenyl)-2(4-sulfophenyl)-2H-tetrazol...

Ngày tải lên: 06/03/2014, 11:20

... kidney cell line drived from the African green monkey. J. Inmunol. 91, 416–424. 26. Chen, C. & Okayama, H. (1987) High-efficiency transformation of mammalian cells by plasmid DNA. Mol. Cell. ... previously [30]. The reporter vector contain- ing the c-fos promoter was kindly provided by U. Moe ¨ ns (University of Tromso, Norway) [31]. The expression vector pcDNA3-myc was generated by inse...

Ngày tải lên: 22/02/2014, 07:20

... promoted by the myristoyl moiety plus electrostatic interactions between positively charged protein side chains and negatively charged membrane phospho- lipids [35,36]. The function of N-myristoylation ... such as cell cycle progression and apoptosis and a lso r emove abnormal and unnecessary intracellular proteins. A major proteolytic system of them in both cytoplasm a nd nucleus of eukary...

Ngày tải lên: 08/03/2014, 16:20

... yeast and Escherichia coli and in mammalian cell types. In higher eukaryotes, it removes an intracellular H + and exchanges it for an extracellular Na + , thereby protecting cells from intracellular ... Rieder 1 , Dyal N. Singh 2 , Luc G. Berthiaume 1,3 and Larry Fliegel 1 Departments of 1 Biochemistry, CIHR Membrane Protein Group, 2 Anatomy and 3 Cell Biology, Faculty of Medicine and Den...

Ngày tải lên: 08/03/2014, 16:20

... (Birmingham University) using Fmoc polyamide chemistry and purified as described previously [28]. The peptide comprising residues 398–414 of human cardiac b-myosin was synthesized by Syntem (Montpellier) ... inhibitory region of human cardiac TnI, hcTnI128–153, dansylated hcTnI128– 153 (T128 replaced by a dansyl group), hcTnI136–148 and the other peptides used in this study (Table 1) were synt...

Ngày tải lên: 17/03/2014, 10:20

... Biology (ZMBP), University of Tu ¨ bingen, Germany; 2 Department of Plant Biology, University of Valencia, Spain The aldo-keto reductase (AKR) superfamily comprises proteins that catalyse mainly ... reaction, are catalysed by enzymes of the aldo-keto reductase (AKR) superfamily [8]. The members of the AKR superfamily are cytosolic, monomeric proteins that catalyse mainly the NAD(P)H- dependen...

Ngày tải lên: 18/03/2014, 01:20

... Res. 32, 1173–1186. 27. Yang, L .Y. , Kuksis, A. & Myher, J.J. (1995) Biosynthesis of chylomicron triacylglycerols by rats fed glyceryl or alkyl esters of menhaden oil fatty acids. J. Lipid Res. ... triacylglycerol is derived from liver cytosolic triacylglycerol through hydrolysis and reesterifica- tion, and possibly by lipolysis from cellular phospholipids [29,30,35] The major source of c...

Ngày tải lên: 23/03/2014, 21:20