Báo cáo y học: "Suppression of nitric oxide production from nasal fibroblasts by metabolized clarithromycin in vitro" potx

... 7:56 http://www.journal-inflammation.com/content/7/1/56 Page 6 of 12 RESEA R C H Open Access Suppression of nitric oxide production from nasal fibroblasts by metabolized clarithromycin in vitro Ayako Furuya 1 , ... subjects. Assay for inducible NO synthases (iNOS) The iNOS levels in cytosol were assayed by commer- cially available human iNOS ELISA kits (R & D S...

Ngày tải lên: 11/08/2014, 03:20

... 7:56 http://www.journal-inflammation.com/content/7/1/56 Page 6 of 12 RESEA R C H Open Access Suppression of nitric oxide production from nasal fibroblasts by metabolized clarithromycin in vitro Ayako Furuya 1 , ... as: Furuya et al.: Suppression of nitric oxide production from nasal fibroblasts by metabolized clarithromycin in vitro. Journal of...

Ngày tải lên: 11/08/2014, 06:22

... sensitivity in non- sensitized guinea pigs and OVA-induced increase in cough reflex sensitivity in sensitized guinea pigs; however, iNOS inhibition caused by ONO1714 partially suppressed the OVA-induced ... needed to clarify the precise mechanism. Background Nitric oxide (NO) may p lay an essential role in regula t- ing airway funct ion and in the pathophysiology of inflamma...

Ngày tải lên: 13/08/2014, 10:20

... reconstitutes in solvent. Because matrine is a strongly hydrophilic and w eakly alkaline drug, the encapsulation efficiency of liposomes for loading matrine is very low when pre- pared by routine ... freeze-drying, was separated by mini-gel columns of Sephadex-G50 prepared in advance. In brief, incubation mixtures of 200μL containing unloaded matrine and RGD-M-LCL wer...

Ngày tải lên: 26/10/2012, 08:57

... [13]. In India, a single dose of BCG vaccine is given within one week of the birth of child. The incidence of TB in India is very high and repeated immu- nization is needed as it is done in other ... analyzed using FlowJo software by gating on the lymphocyte popu- lation in forward scatter (FSC) and side scatter (SSC). The gate was set around the lymphocytes to exclude other...

Ngày tải lên: 11/08/2014, 08:21

... chain reactions by accepting electrons, include α-tocopheral (vitamin E), ascorbic acid (vitamin C), niacin (vitamin B), riboflavin (vitamin B 2 ), vitamin A, and ceruloplasmin [1,2,9]. These systems ... pulmonary disease (COPD), asthma, cystic fibrosis, ischemia-reperfusion injury, drug- induced lung toxicity, cancer and aging [1-4]. Although the use of oxygen may be clinically indicated...

Ngày tải lên: 12/08/2014, 18:21

... supported partly by internal grants from the International Center for Genetic Engineering and Biotechnology and funds from Department of Science and Technology, Government of India. We thank Prof. S. ... regulated in response to multiple stresses and probably has a role at the very beginning of multiple stress signaling pathways [37]. Involvement of CDPKs in stress signaling...

Ngày tải lên: 18/03/2014, 01:20

... spectrometry (MS). P38 and HuR protein kinases have been reported extensively in the general principles of signalling pathways modulated by phosphorylation, mainly by molecular bi ology and western ... phosphorylation of Ser48 in the first protein RNA recognition motif of HuR has potentially a stabilizing effect, exerting a regulatory role on the biological function of protein...

Ngày tải lên: 10/08/2014, 09:22

... metallothionein and inducible nitric oxide synthase (iNOS) are induced by the same factors and the zinc released from metallothionein by NO suppresses both the induction and activity of iNOS. In a search for a ... are various indications of increased flexibility and metal mobility in the b-domaininMT-1[8].Thenaturally bound metal zinc can be displaced by cadmium up to about...

Ngày tải lên: 07/03/2014, 15:20

... V.G., Fielding, P.E. & Egelrud, T. (1973) Cofactor activity of protein components of human very low density lipoproteins in the hydrolysis of tri- glycerides by lipoproteins lipase from different ... stability of apoC-II in the absence of lipid is typical of lipid-free apolipoproteins and may underlie the general propensity of apolipoproteins to form amyloid in vivo...

Ngày tải lên: 24/03/2014, 04:21