Báo cáo y học: "HE3286, an oral synthetic steroid, treats lung inflammation in mice without immune suppression" pptx

... HE3286, an oral synthetic steroid, treats lung inflammation in mice without immune suppression. Journal of Inflammation 2010 7:52. Submit your next manuscript to BioMed Central and take full advantage ... 7:52 http://www.journal -inflammation. com/content/7/1/52 Page 5 of 10 RESEARC H Open Access HE3286, an oral synthetic steroid, treats lung inflammation...

Ngày tải lên: 11/08/2014, 03:20

... confirms an anti-inflammatory activity of HE3286 relevant to lung inflammation. Our observations that HE3286 possesses significant anti-inflammatory activity in both carrageenan and LPS- induced lung ... 7:52 http://www.journal -inflammation. com/content/7/1/52 Page 2 of 10 RESEARC H Open Access HE3286, an oral synthetic steroid, treats lung inflammation in mice w...

Ngày tải lên: 11/08/2014, 06:22

... of inflammatory mediators. • The use of lower tidal volumes may limit pulmonary inflammation in mechanically ventilated patients even without lung injury. Abbreviations ALI: acute lung injury; ... studies suggest that mechanical ventilation (MV) can modify inflammatory responses in patients with acute lung injury. In such patients, with existing pulmon- ary and systemic infla...

Ngày tải lên: 13/08/2014, 20:21

... investigated mainly in patients with already reduced lung function. Thus, aim of this analysis is to determine whether hypertension and antihypertensive medication have an adverse effect on lung ... Myocardial Infarction Registry, Augsburg, Germany. 8 Ludwig-Maximilians-University, Institute of Medical Data Management, Biometrics and Epidemiology, Munich, Germany. 9 Ludwig-Maximilians...

Ngày tải lên: 25/10/2012, 10:45

... meta- choline (Acetyl-β methylcholine chloride, Sigma) was assessed 24 hours after the last intranasal challenge. Briefly, mice were maintained inside a whole-body plethysmograph (Buxco, Troy, NY) ... to naïve mutant mice, increases in airway resistance were also increased to levels exhib- ited in wild type mice. Thus, Th2 effector responses leading to changes in airway resista...

Ngày tải lên: 03/11/2012, 11:24

... haematoxy- lin and eosin or safranin O fast green. Inflammation was graded on a scale from 0 (no inflammation) to 3 (severely inflamed joint) based on infiltration by inflamma- tory cells in the synovium. ... one of the predominant β1 integrins expressed by rheumatoid syno- vial pannus and is expressed by cells in the intimal lining layer and endothelial cells, especially in venules...

Ngày tải lên: 09/08/2014, 08:22

... evidence of increased complement activation either locally within the kidney or systemically in KO MRL mice at any Figure 3 Similar serum autoantibody titers and circulating immune complexes in knockout ... differences in these B-cell subsets between KO MRL mice and CTRL MRL mice. Renal injury MRL mice typically have chronic kidney disease characterized by proteinuria and rena...

Ngày tải lên: 09/08/2014, 10:21

... produced mainly in white adipose tissue and may be the linkage between obesity and insulin resistance. In humans, the role of resistin is not yet fully established. There is evidence that resistin has ... resistin and inflammation. In our study, serum levels of creatinine remained a significant variable to resistin in the multiple regres- sion analyses. Whether this is due to high sy...

Ngày tải lên: 09/08/2014, 10:22

... staining compares the relative intensity of staining of onecoreofaTMAtothatofacontrolcoreonthe same slide. A score of 1 indicates faint staining, 2 indi- cates medium intensity staining, and 3 indicates ... of interest were malignant and originating in the thoracic cavity. Tissues containing a known or suspected malignancy were obtained during standard clinical care through a biopsy or surg...

Ngày tải lên: 10/08/2014, 09:22

... approach in providing valuable insights into the temporal rewiring of the lung transcriptome in response to H1N1 virus. Keywords: Gene Regulatory Network, Time Varying Dynamic Bayesian Network, Immune ... characterized by terms associated to immune response, whereas the rest are mainly involved in metabolic process and system development. Time Varying Dynamic Bayesian Network Mode...

Ngày tải lên: 10/08/2014, 09:22