Báo cáo y học: "Elevated endotoxin levels in non-alcoholic fatty liver disease" potx

... may contribute to low-grade systemic inflammation in insulin resistant states. This study aimed to examine the importance of serum endotoxin and inflammatory markers in non-alcoholic fatty liver ... early indicator of potential liver damage, perhaps negating the need for invasive liver biopsy. As endotoxin may promote insulin resistance and inflammation, interventions aime...

Ngày tải lên: 11/08/2014, 03:20

... may contribute to low-grade systemic inflammation in insulin resistant states. This study aimed to examine the importance of serum endotoxin and inflammatory markers in non-alcoholic fatty liver ... early indicator of potential liver damage, perhaps negating the need for invasive liver biopsy. As endotoxin may promote insulin resistance and inflammation, interventions aime...

Ngày tải lên: 11/08/2014, 06:22

... for the determination of synovial autoantibody and immunoglobulin enrichment in biopsy materials obtained in clinical trials. Immunoglobulin mRNA correlated with synovial protein levels, consistent ... immunoglobulin synthesis. Both anti-CCP and RF-IgM were significantly enriched in synovial tissues containing lym- phoid aggregates. However, in an 8-week study, autoantibody productio...

Ngày tải lên: 09/08/2014, 13:21

... diabetes, in which hyperglycemia and hyperinsulinemia increase resistin expres- sion [10]. Murine resistin is primarily produced in adipocytes, whereas resistin in humans is mainly derived from macro- phages ... adi- pocytes. J Clin Endocrinol Metab 2003, 88:6098-6106. 15. Youn BS, Yu KY, Park HJ, Lee NS, Min SS, Youn MY, Cho YM, Park YJ, Kim SY, Lee HK, Park KS: Plasma resistin concent...

Ngày tải lên: 13/08/2014, 16:21

... inflammatory cytokine inter- leukin-6. Biochem Pharmacol 2000, 60:1185-1195. 33. Cross JT, Benton HP: The roles of interleukin-6 and inter- leukin-10 in B cell hyperactivity in systemic lupus erythemato- sus. ... by preventing FasL-induced apoptosis [62,63], protection against Fas-induced apoptosis by TNF may foster autoimmunity. Along these lines, TNF is indeed necessary for sustaining t...

Ngày tải lên: 09/08/2014, 01:22

... vitamin D insufficiency in 41% of cases in the summer months and even more became vitamin D-deficient during the wintertime. In UCTD patients, the winter levels of vitamin D were considerably lower ... osteoporosis. J Bone Miner Res 1994, 9:1137-1141. 27. Hollis BW: Circulating 25-hydroxyvitamin D levels indicative of vitamin D sufficiency: implications for establishing a new effect...

Ngày tải lên: 09/08/2014, 13:22

... air. Methacholine-induced airway responses measured by whole-body plethysmography in BALB/c mice challenged with saline and ovalbuminFigure 2 Methacholine-induced airway responses measured by whole- body ... airway reactivity were inversely associated in patients with asthma, suggest- ing that airway wall thickening prevents excessive airway narrowing in human subjects in vivo [12]. I...

Ngày tải lên: 12/08/2014, 16:20

... 3-hydroxyacyl coenzyme A dehydrogenase (an enzyme that is involved in β-oxidation of fatty acids) are both significantly reduced in patients with COPD. Citrate synthase activity significantly Respiratory ... independently of lung function [18]. In one study [16], phosphofructokinase (a glycolytic enzyme that is involved in anaerobic metabolism) was sig- nificantly increased in pat...

Ngày tải lên: 12/08/2014, 18:20

... No 3 Ryan and Levy The goal of the present review is to question, by critically evaluating the literature, the practice of routinely treating fever in the ICU patient. The pathophysiology of fever ... mortality, had less organ damage, and had less evidence of acute lung injury. Interestingly, severe sepsis may be associated with a dimin- ished heat shock response. Lymphocytes obtained from...

Ngày tải lên: 12/08/2014, 19:22

... genes in the development of asthma, both being present in the TH2 cytokine locus on chromosome 5q23–31 [2]. Both IL-4 and IL-13 have over- lapping functions, including mediating isotype switching ... ian.hall@nottingham.ac.uk Commentary Interleukin-4 receptor αα gene variants and allergic disease Ian P Hall University Hospital of Nottingham, Nottingham, UK Abstract The interleukin-4 (IL-...

Ngày tải lên: 12/08/2014, 18:20