Báo cáo y học: "Effect of the dual endothelin receptor antagonist bosentan on untreatable skin ulcers in a patient with diabetes: a case report" ppsx

... endothelin receptor antagonist bosentan on untreatable skin ulcers in a patient with diabetes: a case report Fátima Álvarez Reyes * , Cristina Luna Gómez and Manuel Brito Suárez Abstract Introduction: ... Suárez Abstract Introduction: Refractory skin ulcers are a major burden in patients with diabetes. Their pathogenesis is multifactorial, and data incr...

Ngày tải lên: 11/08/2014, 00:23

... fibrocartilage lamellae typical of the AF with associated fibrochondrocytes (Figure 7e and 7g). In the discs that received the ADAMTS5 siRNA, safranin-O staining dem- onstrated the maintenance of ... fibrocartilage lamellae typical of the anulus fibrosus (AF), with associated fibro- chondrocytes (e, g). In the ADAMTS5 siRNA-injected discs, safranin-O staining demon...

Ngày tải lên: 09/08/2014, 14:22

... the manuscript. SK was involved in the statistical analysis and the interpreta- tion of data and helped to draft the manuscript. AK was involved in the acquisition of data, made substantial con- tributions ... All authors read and approved the final manuscript. Appendix In a post-hoc analysis, we additionally analysed all data separately for group classifications depen...

Ngày tải lên: 11/08/2014, 17:20

... substrate. These oligomeric substrates were prepared by hybridizing 1 lm of the 5¢-FAM-labeled 29 base DNA 13 -RNA 4 -DNA 12 (5¢-AATA GAGAAAAAGaaaaAAGATGGCAAAG-3¢) and DNA 15 - RNA 1 -DNA 13 (5¢-AATAGAGAAAAAGAAaAAAGATG GCAAAG-3¢) ... DNA 15 - RNA 1 -DNA 13 (5¢-AATAGAGAAAAAGAAaAAAGATG GCAAAG-3¢) with a 1.5 molar equivalent of the comple- mentary DNA, respectively, as described prev...

Ngày tải lên: 17/03/2014, 17:20

... clearly defined by their amino acid sequence that are autoantibody targets may accelerate progress in the international standard- ization of the autoantibody test, an elusive goal which has been ... diagnostic applications. The present study analysed the technical and clinical accuracy of an anti-SmD1 (amino acids 83–119) and an anti-SmD3 (amino acids 108–122) ELISA for the de...

Ngày tải lên: 09/08/2014, 10:20

... Hepatology 2007, 46:122-129. 18. Sugamura K, Sugiyama S, Nozaki T, Matsuzawa Y, Izumiya Y, Miyata K, Nakayama M, Kaikita K, Obata T, Takeya M, Ogawa H: Activated endocannabinoid system in coronary ... Weyer C, Funahashi T, Tanaka S, Hotta K, Matsuzawa Y, Pratley RE, Tataranni PA: Hypoadiponectinemia in obesity and type 2 diabetes: close association with insulin resistance and...

Ngày tải lên: 11/08/2014, 03:20

... At the early stages of disease, there is a homeostatic increase in the cardiac output as a result of the decrease in cardiac afterload and the stimulation of the sympathetic nervous system. With ... well as an increased cardiac index, heart rate and total plasma volume. AoCLF = acute -on- chronic liver failure; FPSA = fractionated plasma separation, adsorption, and d...

Ngày tải lên: 13/08/2014, 01:20

... [23] were taken into account. The average angle of attachment of the myosin head to the actin filament was % 40° at practically all stages of the hydrolytic cycle of ATP [39]; only a few degrees of difference ... AM–ADP state. In experiments involving MgADP, the activity of adenylate kinase was inhibited by the addition of 50 l M diadenosine pentaphosphate. The...

Ngày tải lên: 24/03/2014, 03:21

... inoculation. The ectomycorrhizal colonization was significantly higher in the dually inoculated treatment than in either of the singly inoculated treatments. acacia / arbuscular mycorrhizas / ectomycorrhizas ... experimental conditions for Austra- lian Acacia. The purpose of this study was to evaluate the functional compatibility of a dual inoculation with A. holos...

Ngày tải lên: 08/08/2014, 14:20

... mammalian fecal matter and detected as plaque formers on lawns of laboratory strains of E. coli B and by using plating conditions that are particularly favorable for clear plaque formation b y T4. E. ... category of t ranspo- sable genes might be capable of generalized transposi- tion without leaving traces of their involvement in the lateral transfer. In both intron-homin...

Ngày tải lên: 12/08/2014, 02:20