báo cáo khoa học: "Formulation of polylactide-co-glycolic acid nanospheres for encapsulation and sustained release of poly(ethylene imine)-poly(ethylene glycol) copolymers complexed to oligonucleotides" pptx
báo cáo khoa học: "Formulation of polylactide-co-glycolic acid nanospheres for encapsulation and sustained release of poly(ethylene imine)-poly(ethylene glycol) copolymers complexed to oligonucleotides" pptx
... not for citation purposes) Journal of Nanobiotechnology Open Access Research Formulation of polylactide-co-glycolic acid nanospheres for encapsulation and sustained release of poly(ethylene imine) -poly(ethylene ... variable release kinet- ics and sizes [28,30-32]. Nanosized PLGA has been formulated for encapsulation of naked plasmid DNA and AO [33,34]....
Ngày tải lên: 11/08/2014, 00:22
báo cáo khoa học: " All-trans retinoic acid inhibits KIT activity and induces apoptosis in gastrointestinal stromal tumor GIST-T1 cell line by affecting on the expression of survivin and Bax protein" pdf
... least by the down-regulation of survivin and up-regulation of Bax (Figure 3A and 3B). Even though XIAP and survivin belong to the same family of apoptotic inhibitors, it is likely that ATRA effected ... expression of survivin, XIAP and Bax protein It is well known that apoptoti c pro cess is regulated by many factors. We investigated the expression of inhibitors of apopt...
Ngày tải lên: 10/08/2014, 10:20
báo cáo khoa học: " Arabidopsis WRKY2 transcription factor mediates seed germination and postgermination arrest of development by abscisic acid" pdf
... This leads to the cessation of cell division and activation of genes encoding seed storage proteins and proteins required to establish desiccation tolerance [6]. Exposure of seeds to ABA during ... expression of Em1 and Em6. wrky2 mutants and wild type showed similar levels of expression for miR159 and its target genes MYB33 and MYB101. Analysis of WRKY2 expres...
Ngày tải lên: 12/08/2014, 03:20
Tài liệu Báo cáo khoa học: Dmrt1 genes at the crossroads: a widespread and central class of sexual development factors in fish pdf
... lack of dmrt1 in mutant mice caused a high incidence of teratomas and resulted in a failure of germ cells to arrest mitosis [56]. Thus, Dmrt1 in mice and similarly Dmrt1bY in medaka appear to be ... molecu- lar activity of Sry is translated into cellular structure and organ morphology. Interestingly, Dmrt1, the ancestor of Dmrt1bY, is one of the downstream effec- tors o...
Ngày tải lên: 14/02/2014, 19:20
Tài liệu Báo cáo khoa học: Interleukin-1-inducible MCPIP protein has structural and functional properties of RNase and participates in degradation of IL-1b mRNA doc
... inter- ferons b and c) contain regulatory elements in the 3¢ UTR that are important for the half life of cytokine mRNAs. For this reason, transcription of genes encod- ing cytokines is not sufficient to guarantee ... dynamics and features of this protein. Role of MCPIP in regulation of the endogenous IL-1b transcript level After identification of a PIN domain in the MCPIP...
Ngày tải lên: 18/02/2014, 14:20
Tài liệu Báo cáo khoa học: "Collecting a Why-question corpus for development and evaluation of an automatic QA-system" pdf
... in too few workers and/ or too slow a rate of data acquisition. Therefore it is of- ten necessary to raise the reward and rely on efficient automatic validation of the data. We have looked into ... material to produce a wide selection of natural questions. The articles varied in topic, degree of formality and the amount of details; from ”Horror film” and ”Christ- mas worl...
Ngày tải lên: 20/02/2014, 09:20
Tài liệu Báo cáo khoa học: "Japanese Dependency Parsing Using Co-occurrence Information and a Combination of Case Elements" pdf
... Verb Candidate Candidate Figure 2: Selection of possible parses for reranking Many methods for reranking the parsing of En- glish sentences have been proposed (Charniak and Johnson, 2005; Collins and ... contingency table of the number of correct bunsetsu (posterior context model × our model) and sentence accuracies before and after rerank- ing, for the entire set of t...
Ngày tải lên: 20/02/2014, 12:20
Báo cáo khoa học: A simple in vivo assay for measuring the efficiency of gene length-dependent processes in yeast mRNA biogenesis doc
... This work was supported by the Ministry of Education and Science of Spain (grant BMC2003- 07072-C03-01 to SC and fellowships to MM-H and to MV), and by the Andalusian Government (CVI271). References 1 ... the draft; we also thank S. Buratowski, T. Kokubo, A. Ponticelli, J. Svejstrup, F. Winston and R. Young for strains and plasmids, and Antonio Garcı ´ a-Susperregui...
Ngày tải lên: 07/03/2014, 12:20
Báo cáo khoa học: Insulin like growth factor-1-induced phosphorylation and altered distribution of tuberous sclerosis complex (TSC)1⁄TSC2 in C2C12 myotubes pptx
... possibility of the inhibition of other lipid or pro- Fig. 1. IGF-1 induced activation of mTOR signaling is prevented by PI3K inhibitor wortmannin and mTOR inhibitor rapamycin. C2C12 myotubes at 4 days of ... activity of the TSC1 ⁄ TSC2 complex and Rheb. Results and Discussion IGF-1-induced activation of mTOR signaling is prevented by PI3K inhibitor wortmannin and mTOR inhi...
Ngày tải lên: 15/03/2014, 11:20
Báo cáo khoa học: Coiled–coil interactions modulate multimerization, mitochondrial binding and kinase activity of myotonic dystrophy protein kinase splice isoforms pptx
... were used to dis- criminate between the different splice isoform partners, we observed homomultimerization by DMPK isoforms E and F, as well as heteromultimerization between isoforms E and F (Fig. ... DMPK isoforms A and B to the endoplasmic reticulum (ER) and DMPK C and D to the mitochondrial outer membrane (MOM) [5,24]. Specific elements in the coiled-coil domain exclusively...
Ngày tải lên: 16/03/2014, 13:20