báo cáo khoa học: "Cationic nanoparticles for delivery of amphotericin B: preparation, characterization and activity in vitro" potx

... effect of increasing PL molecular weight was anincrease in size, an increase in zeta-potential and adecrease of % of cell viability (Table 2). Table 1 summa-rized the different properties of assemblies ... mg/mL and 0.01–10.00 mg/mL,respectively. Firstly, DODAB BF and drug were allowed tointeract for 10 minutes. Thereafter, CMC was added and allowed to interact for 20 minutes before adding PDDA,which ... function of CMC and/ or PDDAconcentrations at 1 h of interaction time between C. albi-cans (1 × 106 cfu/mL) and formulations. Plating on agarplates for cfu counts was performed by taking 0.1 mL of...

Báo cáo khoa học: "Surgical strategies for treatment of malignant pancreatic tumors: extended, standard or local surgery?" potx

... Virchow Klinikum, Universitätsmedizin Berlin, Germany and 2Department of Hepatobiliary Surgery, Shandong Provincial Hospital, Clinical College of Shandong University, Jinan, PR ChinaEmail: ... emerging as a safe and effective option with a low risk for development of exocrine and/ or endocrine insuffi-ciency. TP is not as risky as it was years before and cannowadays safely be performed, ... competing interests.Authors' contributionsMG gave substantial contributions to conception and design, analysis and interpretation of data, has beeninvolved in drafting and revising the...

Báo cáo khoa học: "A Gartner duct cyst of the vagina causing dysuria and dyschezia in a Yorkshire Terrier" pps

... rare in dogs. Siddorn and Mann [9] described dysuria in a four-year old springer spaniel with a cyst in the vagina confirmed to be of urogenital origin and Cauvin et al. [1] reported vaginal ... there was no clinical sign of vaginal discharge or urinary incon-tinence. However, surgical resection of the cyst was rec-ommended to eliminate the dysuria and dyschezia. During surgery the ... abdominal radiography. There was asoft tissue density mass (arrows) caudal to urinary bladder (UB).There was normal colon (C).A Gartner duct cyst of the vagina causing dysuria and dyschezia in...

Tài liệu Báo cáo khoa học: A strategy for discovery of cancer glyco-biomarkers in serum using newly developed technologies for glycoproteomics ppt

... lectin proﬁling (Fig. 3C). In thissystem, 100 ng or less of each candidate is immunopre-cipitated from serum using an antibody against thecore protein moiety of the candidate glycoprotein (Step1 ... difﬁ-cult to distinguish from those involved in wound heal-ing and in ammation. In association with cancergrowth, the stromal cells grow and expand to releasemany glycoproteins into serum. Thus, ... of genes involved in glycosylation and glycansynthesis and the development of bioinformatic tools for their study have been made publicly available asthe Japan Consortium for Glycobiology and...

Tài liệu Báo cáo khoa học: Structural bases for recognition of Anp32⁄LANP proteins doc

... presence of a highly conservedN-terminal domain containing leucine-rich repeats(LRRs), motifs known to mediate protein–protein inter-actions, and of a C-terminal low-complexity region,mainly ... of PP2A-C protrudes out enough to ﬁt well into the grooveformed by the concave surface of the LRR domain.Stabilizing interactions could form between His230 of PP2A-C and Asp119 and Asn94 of ... moleculardocking and two-hybrid screening, we also probed theinteraction with Atx1 and PP2A, and identiﬁed a newpartner of the Anp32a LRR domain.ResultsDescription of the Anp32a LRR domain structurein...

Báo cáo khoa học: Structural basis for recognition of Co2+ by RNA aptamers pot

... available for interactions with RNA ligands,including the N7 atom of purines. Therefore, there isthe possible involvement of the N7 atom of the neigh-boring tandem guanines, G27 and G28 or G37 and G38 ... and G38 in aptamer no. 18, as well as G25 and G26 orG39 and G40 in aptamer no. 20, in Co2+binding.Interestingly, a similar metal ion binding mode tothe tandem guanines has been observed in the ... have been determined with atomic resolution,such as hairpin ribozyme and the P4–P6 domain of thegroup I intron, binding of metal ions in a manneridentical to that of guanine tandems has been...

Báo cáo khoa học: The speciﬁc delivery of proteins to human liver cells by engineered bio-nanocapsules doc

... potential to form a particle.Topology analysis of the C-terminus of L fusionproteinConsisting of 56 amino acids, the primary structure of the C-terminus of the S region is rich in hydrophobicresidues. ... Expression and characterization of a chimericbispeciﬁc antibody against ﬁbrin and against urokinase-type plasminogen activator. J Biotechnol 33, 157–174.Bio-nanocapsules for protein delivery ... aforeign protein using a fusion strategy. One of the pur-poses of inserting a FLAG-tag between the C-terminus of the L protein and EGFP was to study the topology of the fused protein because we expected...

Báo cáo khoa học:Tight estimates for eigenvalues of regular graphs docx

... putting x(v)=xi for allv ∈ Vi and x(v) = 0 otherwise. The main part of the proof is the following lemma.Lemma 1 The following inequality holdsxtAx ≥ [2√d − 1cosα] · xtx.Proof : For ... 2k − i0. Therefore, xiis monotone non-increasing for i ≥ 1, and x2k− i0=0. LetA be the adjacency matrix of G, whose rows and columns areindexed by the vertices of G, and deﬁne a vector ... Therefore,yi+1yi≤i+1i√d−1which isat most 1 for i =2andd = 4, and at most 1 for i =3andd = 3. It follows that for alld ≥ 3, i0+1≤ 3, whereas for d ≥ 5, i0+1=1.Put xi= yi+i0for...

Báo cáo khoa học: "Possible criteria for selection of Quercus suber plus trees" pdf

... variation and breeding of Scots pine in The Netherlands. For Sci 21,341-352Williams CG, Lambeth CC (1989) Bole straight-ness for advanced-generation loblolly pinegenetic ... suberINTRODUCTIONQuercus suber L covers an area of about500 000 ha in Spain. Spain and Portugalproduce 75% of the world’s cork, 25% of which comes from Spain.Many ... the selection of superior trees in of foremost importance (Zobel and Tal-bert, 1983). In a previous article (García-Valdecantos, 1989), the difficulty of choo-...

Báo cáo khoa học: "Repeat hepatectomy for recurrent hepatocellular carcinoma: a local experience and a systematic review" ppt

... extraction of data, assisted in the critical appraisal of included studies and assisted in writing up. ZFY and YCTcarried out the statistical analysis of studies. JMY interpreted data, corrected and ... tumorcapsule formation, vascular invasion, Edmondson-Steinergrade.Major resections were performed more frequently in initial hepatectomy. Combined organ resection was com-mon in initial resection ... after hepatectomy, and then at gradually increasing intervals. Recurrence wasidentified by new lesions on imaging with appearancestypical of HCC or a rising AFP level. When findings onultrasound...

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