báo cáo khoa học: "Intracellular gold nanoparticles enhance non-invasive radiofrequency thermal destruction of human gastrointestinal cancer cells" ppt
... 1 of 9 (page number not for citation purposes) Journal of Nanobiotechnology Open Access Research Intracellular gold nanoparticles enhance non-invasive radiofrequency thermal destruction of human ... nanotube-enhanced thermal destruction of cancer cells in a noninvasive radiofrequency field. Cancer 2007, 110:2654-2665. 25. Bhattacharya R, Patra CR, Verma R, K...
Ngày tải lên: 11/08/2014, 00:22
... Simon MC (2004) Regulation of transcription and translation by hypoxia. Cancer Biol Ther 3, 492– 497. 9 Semenza GL (2003) Targeting HIF-1 for cancer ther- apy. Nat Rev Cancer 3, 721–732. 10 Semenza ... take place in HepG2 cells. Impairment of the regulation of the extracellular content and the increase of its uptake induced by hypoxia show that alteration of pyruvate metabolis...
Ngày tải lên: 18/02/2014, 16:20
... functions of human nervous system in light of the Gene Ontology (GO) profile of human orthologs. Results Characters and distribution of LIRs in human autosomes We identified 2551 LIRs in human autosomes ... and human. The results obtained demonstrate that human orthologs have relatively more LIRs, most of which are human- specific. These human- specific LIRs are probably es...
Ngày tải lên: 07/03/2014, 00:20
Báo cáo khoa học: Amino acids at the N- and C-termini of human glutamate carboxypeptidase II are required for enzymatic activity and proper folding pptx
... Konvalinka 1,2 1 Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Prague, the Czech Republic; 2 Department of Biochemistry, Faculty of Natural Science, Charles ... domains to the structure/ function of recombinant human GCPII. We cloned 13 mutants of human GCPII that are truncated or extended at one or both the N- and C-termini of...
Ngày tải lên: 07/03/2014, 15:20
Báo cáo khoa học: Sp1 and Sp3 are involved in up-regulation of human deoxyribonuclease II transcription during differentiation of HL-60 cells pptx
... Coaddition of the two antibodies resulted in the loss of bands C1, C2, and C3 (lane 13). In contrast, the use of a control monoclonal antibody against SREBP did not affect the formation of any of the complexes ... single mutation of GC-I, GC-II, or GC-III resulted, respectively, in a significant reduction of 48, 70, or 36% in luciferase activity (P < 0.05), while mutation of...
Ngày tải lên: 23/03/2014, 17:21
Báo cáo khoa học: From meiosis to postmeiotic events: Alignment and recognition of homologous chromosomes in meiosis ppt
... [39]. Contribution of homologous recombination to pairing Formation of DSBs of DNA is essential for the subse- quent recombination of homologous chromosomes. In meiosis, DSBs of DNA are deliberately ... recombination of homolo- gous chromosomes is important for ensuring the cor- rect segregation of chromosomes during the two rounds of nuclear division: reductional segregation...
Ngày tải lên: 29/03/2014, 08:20
Báo cáo khoa học: A novel G-quadruplex motif modulates promoter activity of human thymidine kinase 1 docx
... only TKQ1 forms a significant population of G-quadru- plex(es). Thermal stability of TKQ1 – UV melting experiments To assess the thermal stability of the structures of TKQ1, TKQ1m, TKQ2 and TKQ2m, we ... presence of peaks at 10–12 p.p.m. indi- cated the existence of G-quadruplexes (Fig. S1). A novel G-quadruplex motif of TKQ1 – TDS and CD signatures Thermal difference spect...
Ngày tải lên: 29/03/2014, 21:20
Báo cáo khoa học: A novel phosphorylated glycoprotein in the shell matrix of the oyster Crassostrea nippona pptx
... 5¢-region of the nucleotide sequence completely matched that of fragment A. Next, 5¢-rapid amplification of cDNA ends (5¢- RACE) revealed the presence of one positive clone (fragment C) with a length of ... those of the above-men- tioned fragments, A, B and C. After addition of the remaining sequences, namely approximately 100 bp of the 5¢-region and 110 bp of the 3¢-region,...
Ngày tải lên: 30/03/2014, 04:20
Báo cáo khoa học: Mutant recombinant serpins as highly specific inhibitors of human kallikrein 14 ppt
... (velocity) of hK14 were obtained by adding 20 l M of fluorescent substrate. Fractional velocity corresponds to the ratio of the velocity of the inhibited enzyme (v i ) to the velocity of the uninhibited ... intercept of the linear regression analysis of fractional velocity (velocity of inhib- ited enzyme reaction (v i ) ⁄ velocity of uninhibited enzyme reaction (v 0 )) versus...
Ngày tải lên: 30/03/2014, 11:20
Báo cáo khoa học: "Hybridization and mating system in a mixed stand of sessile and pedunculate oak" pptx
... explained by the fertilization of a portion of female flow- ers with pollen of Q petraea; on the con- trary, the causes of the shift in frequencies of Q petraea progeny are ... spite of the pollen environment, which is composed of similar proportions of conspecific versus foreign plants of the 2 species (mother trees are encircled by...
Ngày tải lên: 08/08/2014, 19:21