báo cáo khoa học: " Stability of beating frequency in cardiac myocytes by their community effect measured by agarose microchamber chip" pot

... citation purposes) Journal of Nanobiotechnology Open Access Short Communication Stability of beating frequency in cardiac myocytes by their community effect measured by agarose microchamber chip Kensuke ... constant frequency of beating. The result of nine sets of different samples (one of the five sets was shown in Figure 5) summarized in Figur...

Ngày tải lên: 11/08/2014, 00:22

... tetracyclines, lacking antibiotic activities, may inhibit MMPs by binding to metal ions such as zinc and calcium. This family of inhibitors, including metastat (COL-3), minocycline and doxycycline, cause ... anti-apoptotic effect by activating indirectly the serine ⁄ threonine kinase Akt ⁄ protein kinase B through the signaling cascades of EGFR and IGFR [20,32]. MMPs also promote ap...

Ngày tải lên: 15/03/2014, 00:20

... the intraindividual and interindivi- dual variations were determined in the four healthy donors and in the 79 patients. Intraindividual variation for healthy donors was always lower than interindividual variation ... of peripheral blood lymphocytes from patients determining the radiation induced apoptosis with annexin V/propidium iodide staining. b values observed define an individual r...

Ngày tải lên: 09/08/2014, 10:20

... in the gastrointestinal tract is thought to be one of the factors that may contribute to the allergenic potential of food proteins by allowing sufficient intact (or a large fragment of) protein ... digestion,  25% of the allergen remained intact, whereas 50% corresponded to a ‘large frag- ment’ (M r 6400) comprising mainly peptides matching with the large chain linked together by...

Ngày tải lên: 30/03/2014, 15:20

... abdomen, and pelvis by using electronic portal imaging. In addi- tion, the effect of different frequencies of online verifica- tion (no online verification, online verification once a week, online verification ... the corresponding SM calculated. The data should help the physician to choose the most clinically appropriate frequency of online verifica- tion for the individual pat...

Ngày tải lên: 09/08/2014, 09:21

... SJ (2008) Regulation of hepatic drug-metabolizing enzyme genes by Toll-like receptor 4 signaling is independent of Toll-interleukin 1 receptor domain-containing adaptor protein. Drug Metab Dispos ... reperfusion injury [14]. In our studies, we employed GdCl 3 to inactivate KCs based on the findings of other investigators showing the destruction of KCs after the intravenous administ...

Ngày tải lên: 14/02/2014, 18:20

... long-chain saturated fatty acids (SFAs) led to increased expression of proin- flammatory cytokines, inhibition of insulin signaling, induction of endoplasmic reticulum (ER) stress, and promotion of ... incubation periods. Interestingly, the interruption of TAG synthe- sis preceded the appearance of toxic effects, supporting the notion that it constitutes the initiating event in t...

Ngày tải lên: 14/02/2014, 22:20

... adjusted by several sphingo- lipid production pathways, such as de novo ceramide synthesis by serine palmitoyltransferase and cleavage of sphingomyelin by sphingomyelinase, as well as by Cer metabolism ... role in keratinocyte sur- vival during skin wound healing, and PPARb expres- sion is elevated at injury sites [10,15]. We investigated whether skin barrier disruption by tape-...

Ngày tải lên: 18/02/2014, 18:20

... allow TFIIIB binding in an active state (i.e. capable of interacting with TFIIIC to stabilize binding) in the case of tRNA Gly 1 -1 and in an inactive state (incapable of efficient interaction with TFIIIC ... another 15 min. Binding reactions were termin- ated by the addition of gel loading buffer and electrophore- sed on 6% polyacylamide gels at 4 °C and visualized in Phosph...

Ngày tải lên: 20/02/2014, 02:21

... these three arginines in TClpB. By combining an arginine mutation with the WalkerA mutation in the other AAA+ module, we tested the roles of the arginines in ATP binding and hydrolysis in each module. ... of the hexameric form, but not for the ATP-induced motion of the middle domain. Results The conserved arginines are not involved in nucleotide binding To examine the roles...

Ngày tải lên: 06/03/2014, 00:20