báo cáo khoa học: "Response to imatinib rechallenge in a patient with a recurrent gastrointestinal stromal tumor after adjuvant therapy: a case report" pdf

... [http://jco.ascopubs.org/content/26/4/626.full?sid=f8b759be-e 0a9 -4e0d-ba 3a- 1807629ebd74].doi:10.1186/1752-1947-5-504Cite this article as: Kang: Response to imatinib rechallenge in a patient with a recurrent gastrointestinal stromal tumor after adjuvant therapy: a case report. Journal of Medical Case Reports ... CAS E REP O R T Open AccessResponse to imatinib rechallenge in a patient with a recurrent gastrointestinal stromal tumor after adjuvant therapy: a case reportYoon-Koo KangAbstractIntroduction: ... results indicate that imatinib sensitivity can be maintained in a patient with previous exposure to adjuvant imatinib therapy.Introduction Gastrointestinal stromal tumors (GIST) are the most com-mon...

báo cáo khoa học: " Response to dexamethasone is glucose-sensitive in multiple myeloma cell lines" pps

... run in triplicate for analysi s. Cellswere harvested and each sample split into three aliquotsfor RNA isolation, ROS and TRX activ ity analysis. TotalRNA was isolated using Aquapure RNA isolation ... its efficacy particularly in combination with other agents remains unclear. A betterunderstanding of these pathways may help in improvingthe efficacy and reducing the toxicity of DEX, a drugstill ... h. Data is represented as fold change over 20 mM baseline, with > 1 fold changeindicating an increase over baseline and < 1 a decrease over baseline levels. Multiple myeloma-derived ARH77,...

Tài liệu Báo cáo khoa học: "Learning to Recognize Tables in Free Text" pptx

... cl, j is a space character and ci,j is a space character F2 F3 F4 ci,,j is an alphanumeric character or a special character, and ci,j is a space character ci,,j is a space character, and ci,j ... cij is a space character and ei,jq_ 1 is a space character; or ci,j is a special character and ci,j+l is a special character cij is an alphanumeric character or a special character, and ci,j+l ... constitute tables. Lines with only space characters or special characters tend to delimit tables or are part of tables. Lines within a table tend to begin with some number of leading space characters....

Tài liệu Báo cáo khoa học: NMR structure of AII in solution compared with the X-ray structure of AII bound to the mAb Fab131 pptx

... there are threegeneral approaches that can be utilized to extract structuralinformation [4]: a peptide (ligand)-based approach, a receptor-based approach, and approaches that target theligand–receptor ... a high incidence of Asx motifs with the aspartate orasparagine as the ﬁrst residue. Speciﬁcally Asx motifsoccur with the side chain aspartate carboxyl grouphydrogen-bonded to a main chain NH ... that it was not generated against AII, but ratheragainst an anti-idiotypic Ig with a mAb to AII, whichrenders this antibody an anti-(anti-idiotypic) Ig. The highafﬁnity for AII of the original...

Báo cáo khoa học: Sensitivity to Hsp90-targeting drugs can arise with mutation to the Hsp90 chaperone, cochaperones and plasma membrane ATP binding cassette transporters of yeast docx

... using rabbit polyclonalantisera raised against the bacterially expressed Hsp82 and Sba1p of yeast.Hsp90 ATPase assaysHsp90 ATPase assays used a regeneration coupled enzymeassay [24], each ... can arise with mutational alteration to the Hsp90 chaperone machine.AcknowledgementsWe are indebted to Susan Lindquist, Didier Picard, Richard Gaber,and Karl Kuchler for gifts of strains. Part ... to Hsp90 inhibitor resistance. Strains lacking two ofthe major plasma membrane ATP-binding cassette (ABC)transporter determinants of drug resistance (Pdr5p andSnq2p [46]) were streaked onto...

Báo cáo khoa học: "Syntax-to-Morphology Mapping in Factored Phrase-Based Statistical Machine Translation from English to Turkish" ppt

... Birchet al. (2007) have integrated more syntax in a factored translation approach by using CCG su-pertags as a separate factor and have reported a 0.46 BLEU point improvement in Dutch -to- English ... MorphologyBLEU Scores, with 8-gram tag LM and 3/4-gramroot LMs3.2.4 Augmenting the Training Data In order to alleviate the lack of large scale parallelcorpora for the English–Turkish language pair, weexperimented ... weexperimented with augmenting the training data with reliable phrase pairs obtained from a previousalignment. Phrase table entries for the surface fac-tors produced by Moses after it does an alignmenton...

Báo cáo khoa học: "End-to-End Evaluation in Simultaneous Translation" pptx

... June.Donna Gates, Alon Lavie, Lori Levin, Alex. Waibel,Marsal Gavalda, Laura Mayﬁeld, and Monika Wosz-cyna. 1996. End -to- end evaluation in janus: A speech -to- speech translation system. In Proceed-ings ... simultaneoustranslation system also needs time and effort forpreparation and adaptation towards the target ap-plication, language and domain. However, onceadapted, it can be easily re-used in the same ... an-swers are analysed: for each answer a Spanish val-idator gives a score according to a binary scale (theinformation is either correct or incorrect). This al-lows us to measure the information...

Báo cáo khoa học: "How to Parse Gaps in Spoken Utterances" docx

... input data, the parser must be able to start its operation at any point within the chart. In general, our main parsing direction is from left to right. With respect to the expansion of islands, ... vari- ous parsing strategies in a transparent way. We discuss which features have been incorporated into the parser in order to process speech data, in particular the abi- lity to perform ... grammar does not influence complexity, but its branching factor, which is a measure for its degree of nondeterminism, acts as a proportionality factor. V. ISLAND PARSING WITH A CHART In...

Báo cáo khoa học: "RESPONDING TO USER QUERIES IN A COLLABORATIVE ENVIRONMENT*" docx

... that influence the domain plan and how it is constructed, the evaluator must be a reactive planner that interacts with the user to obtain information used in building the evaluation meta-plan. ... to analyze utterances and construct a dialogue model[6]. Lambert's system automatically adds to the dialogue model all actions inferred from an utterance. However, we argue that in a ... include a system that responds to the user's utterances in a collaborative manner. Each utterance by a participant constitutes a proposal intended to affect the agents' shared plan....

Báo cáo khoa học: "Resistance to water stress in seedlings of eight European provenances of Pinus halepensis Mill" potx

... provenances of Pinus halepensis Mill.Roberto Calamassi a, *, Gianni Della Rocca a , Mauro Falusi a , Elena Paolettiband Sara Stratib a Dipartimento di Biologia Vegetale, Piazzale delle Cascine 28, ... biologi-cally dry, according to Gaussen’s xerothermal index) andtemperate climate, with a sub-dry period and an absenceof biologically dry days [37], with a mean annual rainfallof 846 mm and a mean ... increased, starting already at moderatelevels of stress, and always maintaining this value at a slightly more negative level than the substrate’s waterpotential. This tendency to a reduction in...

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