... example, asparagine to aspartic acid, orglutamine to glutamic acid changes [14]. The a- conotoxinsEpI, PnIA, GIC, GID, AnIA and AnIB contain pairs of asparagine residues [5,10,21,23,24] (Table ... under-hydroxylated variants suchas in the example of TVIIA [28] and perhaps the modifi-cation may not be critical. However there was no evidence of a variant of GID with proline in place of the singlehydroxyproline ... subclasses within the neuronally activemembers of the a- conotoxin family [ 9a] .There are many interesting features of the biology of Conus species and the functional applications of the a- conotoxins...