báo cáo khoa học: "Targeted therapy in lymphoma" docx
báo cáo khoa học: "Targeted therapy in lymphoma" docx
... proteins involved in the regulation of cell
growth [15]. The proteasome activates nuclear factor-B
(NF-B) signaling by degrading IB kinase (eg, the NF-
B inhibitory protein), resulting in the ... reported in 65% of patients [35].
Combination therapy with bortezomib is being evalu-
ated further in an ongoing open-label, international
phase III study. In this study, standard R-C...
Báo cáo khoa học: " Radiation therapy in primary orbital lymphoma: a single institution retrospective analysis" docx
... reported
in any patient. Keratitis occurred in 5 patients (10.6%),
xerophthalmia in 9 (19.1%), cataract in 12 (25.5%), cor-
neal ulceration occurred in one patient (2.1%), and minor
retinopathy in ... to obtain local con-
trol in the range of 89-100% using radiotherapy in low or
moderate doses as 25-36 Gy. A summary of findings of
some of published major studies on the issue i...
báo cáo khoa học: " Maintenance therapy in NSCLC: why? To whom? Which agent?" ppt
... 2) continuing only the third-genera-
tion non-platinum compound used in the induction
regimen; 3) switching to a different agent after induction
therapy.
Continuing first-line induction therapy
The ... reported in the ASCO guideline update in 2009
[17,18].
Continuing the same non-platinum compound
used in the induction regimen
In patients responding or stable after the induction...
Báo cáo khoa học: "Finding Contradictions in Text" docx
... polarity for textual infer-
ence. In Proceedings of ICoS-5.
Olivia Sanchez-Graillet and Massimo Poesio. 2007. Dis-
covering contradiction protein-protein interactions in
text. In Proceedings of BioNLP ... applied
to intelligence reports, demonstrating which infor-
mation may need further verification. In bioinfor-
matics where protein-protein interaction is widely
studied, automaticall...
báo cáo khoa học: "Individualized therapies in colorectal cancer: KRAS as a marker for response to EGFR-targeted therapy" docx
... specific sequences that are
involved in dimerization, while the intracellular domain
is a catalytic site that has tyrosine kinase activity. EGFR
binds soluble ligands, including epidermal growth factors
(EGFs) ... a for-
ward-thinking design when it was conceived, because the
EPIC study showed activity of cetuximab in second line
therapy for irinotecan-naïve patients. With more convinc-...
Báo cáo khoa học: Targeted disruption of one of the importin a family members leads to female functional incompetence in delivery docx
... the
importin a3 subfamily includes importin a3 (karyoph-
erin a4, Qip1) and importin a4 (karyopherin a3,
Qip2); and the importin a5 subfamily includes impor-
tin a5 (karyopherin a1, NPI-1) and importin ... [4].
These importin a isoforms have distinct binding
characteristics for various NLS-containing proteins
in vitro [5–7]. Furthermore, previous studies indicated
that the importin a isofor...
Báo cáo khoa học: "Combination therapy with docetaxel and S-1 as a first-line treatment in patients with advanced or recurrent gastric cancer: a retrospective analysis" docx
... treatment regimens have been
reported, including 5-fluorouracil, doxorubicin, and
mitomycin (FAM) [4], epirubicin and cisplatin (CDDP) in
combination with continuous infusion of 5-fluorouracil
(ECF) ... trans-
ferase was increased when docetaxel was administered in
combination with S-1. In addition, in recent retrospective
and phase I/II study [13,14,24], the combination therapy
dem...
Báo cáo khoa học: "Postmastectomy irradiation in breast in breast cancer patients with T1-2 and 1-3 positive axillary lymph nodes: Is there a role for radiation therapy" ppsx
... premenopousal in no-RT
group. Interestingly any patient with LRR had no extra-
nodal extension in our series. As for DM, lymphatic inva-
sion had an impact on LRRs existing in 5 out of 6 (83%).
All LRRs in ... above the seventh rib. Any relapse
involving the axillary lymph nodes, and/or other nodes
in the infra or supraclavicular fossa or in the internal
mammary chain was consider...
Báo cáo khoa học: "Dose distribution in the thyroid gland following radiation therapy of breast cancer-a retrospective study" ppsx
... median VolTotGy in Controls was 2.3 times above VolTotGy in Cases (r = 0.003), with
large inter-individual variations in both groups. The volume of the thyroid gland receiving < 30 Gy in Controls ... This resulted in significantly
smaller absolute thyroid sub-volumes receiving ≥ 30 Gy
in Cases than in Controls. The median of the individual
mean thyroid dose was 31 Gy [22Gy-42...
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