báo cáo khoa học: "Lobaplatin arrests cell cycle progression in human hepatocellular carcinoma cells" ppt

... of lobaplatin in terms of cell cycle kinetics. The results suggested that (i) lobaplatin could inhibit the proliferation of human HCC cells through arresting cell cycle progression in G 1 and ... to oxaliplatin in these human HCC cell lines. The dose-response curve of lobaplatin in SMMC-7721 cells was specially shown in Figure 1B. In a range of 0.25 to 4.5 μg/ml, l...

Ngày tải lên: 10/08/2014, 22:21

... stained cells in the tumor, where: 0 = no stain, up to 10% positive cells. 1 = light stain, 11-25% positive cells. 2 = moderate stain, 26-50% positive cells. 3 = heavy stain 51-75% positive cells. ... our understanding of the development and progression of all human malignancies [14], this was explored in our laboratory in this study protocol. Cell Cycle The cell cycle is a...

Ngày tải lên: 09/08/2014, 03:21

... phase of the cell cycle, we sought to determine if loratadine modifies radiosensitivity in several human tumor cell lines with emphasis on human colon carcinoma (HT29). Methods: Cells were treated ... 74 to 58%). Interestingly, despite inducing a G2 block, loratadine- treated cells clearly dominated the cell cycle delay and radiation with loratadine did not cause additional...

Ngày tải lên: 09/08/2014, 10:20

... effects remains unclear. Methods and Results: Herein, we investigated whether LA elicits its anti-tumor effects by inducing cell cycle arrest and cell death in human promyelocytic HL-60 cells. The ... arrest by altering the expressions of specific signaling proteins To assess LA-induced cell growth suppression is mediated via alterations in cell cycle, we evaluated the cell...

Ngày tải lên: 10/08/2014, 22:20

... oocytes are in the G0/G1 phases of the cell cycle. Another study found that the rate of cell growth in the G0/G1 phases decreased in actively growing cells, as compared to that of cells that ... that can secrete valuable proteins or pharmaceuticals used in human medicine in their urine or milk [3,14,17], as well as to establish embry- onic stem cell lines in several...

Ngày tải lên: 07/08/2014, 20:23

... renal cell carcinoma during sunitinib treatment. Conclusion: In the advancing era of molecular therapy of solid tumours, sunitinib has demonstrated significant efficacy in the post-cytokine setting ... reproduction in any medium, provided the original work is properly cited. Case report Abscess formation mimicking disease progression, in a patient with metastatic renal cell c...

Ngày tải lên: 09/08/2014, 03:21

... shown to bind malo- nyl-CoA [47]. Interestingly, its tissue distribution was restricted to the brain. Being a malonyl-CoA binding protein that is restricted to neurons made it a tantaliz- ing effecter ... although maintaining a lower food intake. This is accompanied by a suppression in energy expenditure. These data suggest that CPT1c can integrate carbohydrate and lipid nutrient sensing i...

Ngày tải lên: 14/02/2014, 22:20

... 3T3-L1 cells were cultured in DMEM containing 10% fetal bovine serum. OP9 cells were grown in aMEM containing 20% fetal bovine serum. C2C12 cells were maintained in DMEM containing 10% fetal bovine ... or without hematoxylin staining. In hypoxia experiments, 3T3-L1 cells were maintained in a hypoxia chamber (Invivo 400; Ruskinn Inc., Cincinnati, OH, USA) constantly maintained at 1%...

Ngày tải lên: 18/02/2014, 08:20

... N- gram Weighting: Reducing Training Data Mismatch in Cross-Domain Language Model Estimation. In Pro- ceedings of the Conference on Empirical Methods in Natural Language Processing, pages 829–838. Dietrich ... second point in constructing our language model, an advantage of our approach over subsampling is that we use our entire training corpus, and in so doing compromise between mi...

Ngày tải lên: 20/02/2014, 04:20

... min) at 37 °C. The concentration of the biotinylated Ig remaining on the cell surface was then quantified by measuring the binding of [ 125 I]Streptavidin. In the absence of bTSH, a very weak internalization ... intracellular staining of the cells is also observed, probably correspond- ing to the precursor protein that has been shown to accumulate in the endoplasmic reticulum [10]. For c...

Ngày tải lên: 21/02/2014, 00:20