báo cáo khoa học: "Pharmacokinetic targeting of intravenous busulfan reduces conditioning regimen related toxicity following allogeneic hematopoietic cell transplantation for acute myelogenous leukemia" potx

... Pharmacokinetic targeting of intravenous busulfan reduces conditioning regimen related toxicity following allogeneic hematopoietic cell transplantation for acute myelogenous leukemia. Journal of Hematology ... Access Pharmacokinetic targeting of intravenous busulfan reduces conditioning regimen related toxicity following allogeneic he...

Ngày tải lên: 10/08/2014, 22:21

... activities of cells transformed with various CYP1A1s, and (C) represents the BROD activity of cells transformed with CYP2B1 constructs as indicated. N. B. V. Sepuri et al. Mitochondrial targeting of ... important in mito- chondrial targeting of the protein in COS cells. In the second approach, we tested the level of mitochondrial targeting of S129A mutant CYP2E1 in transform...

Ngày tải lên: 18/02/2014, 16:20

... Biochem. 270) 2829 of mitoDC-81 as a bulk culture of 143B cells grown in 500 n M mitoDC-81 for 6 weeks had normal rates of mitochondrial respiration (data not shown). Concentra- tions of mitoDC-81 ... accumulation for every 61.5 mV of membrane potential. This leads to a millimolar concentration of mitoDC-81 within mitochondria on incubation of cells with high nanomolar to mi...

Ngày tải lên: 20/02/2014, 11:20

... Department of Medicine, Tufts University School of Medicine, Boston, MA, USA 3 Department of Biochemistry, Tufts University School of Medicine, Boston, MA, USA One of the key characteristics of inflammation ... randomized trial of an anti-CD18 antibody in conjunction with recombinant tissue plasminogen activator for acute myocardial infarction: limitation of myocardial infa...

Ngày tải lên: 07/03/2014, 12:20

... involvement of SecA in the targeting process, we compared the azide sensitivity of preHoloHiPIP targeting with that of the targeting of the Fig. 5. Requirements for membrane targeting of HiPIP. ... description of membrane targeting of a [4Fe)4S] cluster-containing folded protein. This mem- brane -targeting pathway may be of importance for the biogenesis of mem...

Ngày tải lên: 23/03/2014, 21:20

... presence of increasing concentrations of the compounds did not significantly affect their LD 50 values. However, a shorter duration (15 min) of incubation of the cells in the presence of H4-(86–100) ... dilutions of the cells (1.0, 0.5, 0.1, 0.05, 0.01 and 0.005 · 10 6 CFUvÆmL )1 ) were also made in the absence of drug for standardization of the growth assay. After preincubat...

Ngày tải lên: 18/02/2014, 14:20

Ngày tải lên: 07/08/2014, 17:22

... R.E., Van Cleve K., Seasonal patterns of soil respiration and CO 2 evolution following harves- ting in the white spruce forests of interior Alaska, Can. J. For. Res. 17 (1987) 304–310. [14] Hendrickson ... Nutrient cycling following whole tree and conventional harvest in nor- thern mixed forest, Can. J. For. Res. 19 (1989) 725–735. [15] Hendrickson O.Q., Chatarpaul L., Robinson J.B...

Ngày tải lên: 08/08/2014, 14:21

... - 491 488 489 513 522 528 550 552 532 585 661 663 664 726 726 537 492 547 416 526 556 a b Journal of Hematology & Oncology 2009, 2:17 http://www.jhoonline.org/content/2/1/17 Page 2 of 12 (page number not for citation purposes) Introduction Allogeneic hematopoietic cell transplantation ... diagnosis of acute GVHD (aGVHD) and to pro- vide prognostic information. Paczesny e...

Ngày tải lên: 10/08/2014, 22:20

... spectroscopy the conformational properties of HpPex5p, the PTS1 receptor of the yeast H. polymorpha. Fluorescence emission spectra revealed a pH dependence of Trp fluorescence of HpPex5p, indicative of pH driven ... Laboratory of Biochemistry, Wageningen University, the Netherlands; 4 Centre for Molecular and Biomolecular Informatics, University of Nijmegen, the Netherlands; 5...

Ngày tải lên: 21/02/2014, 00:20