báo cáo khoa học: "Plasma protein C levels in immunocompromised septic patients are significantly lower than immunocompetent septic patients: a prospective cohort study" pdf

... purposes) Journal of Hematology & Oncology Open Access Research Plasma protein C levels in immunocompromised septic patients are significantly lower than immunocompetent septic patients: a prospective ... and/or pul- monary embolism c) Patients on Warfarin (Protein C is a vitamin K depend- ent protein) d) Disseminated Intravascular Coagulation (DI...

Ngày tải lên: 10/08/2014, 22:20

... expression at D5 after LPS injection. Introduction Septic shock is often associated with vascular damage, hae- mostasis activation and development of disseminated intra- vascular coagulation leading ... activating PC. Acti- vated PC (aPC) inactivates the coagulation cofactors Va and VIIIa through proteolytic degradation, thereby limiting thrombin generation. aPC produces then anti-thromboti...

Ngày tải lên: 12/08/2014, 23:22

... major challenge in critical care medicine. The recently introduced recombinant human activated protein C (APC) remarkably improved the outcome of septic patients. The influence of APC on intestinal ... There is an increasing body of evidence that activated protein C (APC) exerts beneficial effects in the microcirculation. Human plasma-derived and human cell-produced recombinant...

Ngày tải lên: 13/08/2014, 03:20

... vibra- tional spectroscopic characteristics of phytochromes assembled with the same chromophore are remarkably similar, whereas significant and characteristic changes are associated with subtle changes in ... Optics, Dunedin, FL, USA). The eluate was finally concentrated using a C1 8 Sep-Pak cartridge and the PCB was stored at )80 C in darkness. PCB was quantified by UV-Vis absorbanc...

Ngày tải lên: 30/03/2014, 11:20

... (MCV), red blood cell mean corpuscular haemoglobin concentration (MCHC) and platelet count (PC). Analysed serum bio- chemical parameters included alanine aminotransferase (ALAT), albumin, alkaline ... ice and stored at - 70 C until analysis. C- reactive protein was determined by a commercially available canine sandwich ELISA (Canine CRP ELISA kit, TriDelta Diagnostics Inc., Plains, NJ,...

Ngày tải lên: 12/08/2014, 18:21

... quartile). Note that not all laboratory parameters could be obtained in all patients at each time-point. aPTT, activated partial thromboplastin time; AT, antithro mbin; CRP, C reactive protein; ... involved in study design and data analysis. BE was involved in study design and data collection. UM was involved in data management, statistical analysis and data interpretation. RS wa...

Ngày tải lên: 13/08/2014, 21:21

... with the ClpP1 antibody. The ClpP1 H and ClpP1 L bands decrease slowly and concomitantly after 24 h, indicating that both are stable in the cell. As a loading control, a duplicate blot was reacted ... public databases and the in- house’ Clp database using fasta3. Growth of Chlamydomonas and subcellular fractionation Chlamydomonas reinhardtii wild-type and cell-wall less mutant (cw15)...

Ngày tải lên: 16/03/2014, 23:20

... roles in chromatin structure, regulating pro- cesses such as transcriptional activation or silencing of genes, DNA repair, and mitotic and meiotic condensa- tion of chromatin. Recently, a novel covalent ... panel). The nuclear compartment was stained using DAPI, and the cytoplasm was stained using rhodamine phalloidin. Images entitled ‘Merged’ were created by overlaying images obtained by...

Ngày tải lên: 23/03/2014, 15:20

... and compliance with re gulatory agencies or quality assurance initiatives in the workplace, may lead healthcare professionals to incorporate research evidence into clinical practice [2]. A patient-centered ... not at all, and only 13.3% of therapists integrate research in clinical decision making 6+ times in a typical month. The actual ra te of research use in clinical decision ma...

Ngày tải lên: 10/08/2014, 10:23

... study. Name Sequence (residues 91–100) WT GGGAGGGGGG polyAla *SA*AAAAA* AGG AAA******* GAG ****AAA*** GGA *******AAA GAA ****AAAAAA AGA AAA****AAA AAG AAA*AAA*** GGD *******DDD GGE *******EEE GGL *******LLL GGN ... suggest that relatively compact and nonhydrophobic side chains in this particular region play a crucial role in correct sorting of Toc75. Abbreviations mtHsp70, mitochondrial...

Ngày tải lên: 19/02/2014, 07:20