báo cáo khoa học: "Different altered stage correlative expression of high abundance acute-phase proteins in sera of patients with epithelial ovarian carcinoma" pptx

... Relative expression of APPs in the sera of patients in different clinical stages of EOCa. Serum proteins *Fold changes and statistical significance Probability P Stage I Stage II Stage III Stage ... Hashim OH: Profiling of serum and tissue high abundance acute-phase proteins of patients with epithelial and germ line ovarian carcinoma. Proteome Sci...

Ngày tải lên: 10/08/2014, 22:20

... drugs (norephinefr- ine 0.25 μg/kg/min and levosimendan 0.2 μg/kg/min). The time taken for the intervention was 260 min glob- ally, including 55 min of aortic clamp and 125 min of ECC. The total ... manoeuvre in the pressure-controlled mode at an inspiratory pla- teau pressure of 45 cm of water, a PEEP of five cm of water, a respiratory rate of ten breaths per minute and a 1:1...

Ngày tải lên: 11/08/2014, 02:21

... to interact with the N-terminus of the peptide itself but not with the enzyme. Interestingly, a hydrophobic interactionofthesidechainofMet1ofTat(1–9)withthe phenyl ring of Ala-Pro-pNA may hinder ... different binding sites at the enzyme; furthermore, we could show that single amino acid substitutions at certain positions of the parent structure alter the mode of inhibition indicati...

Ngày tải lên: 20/02/2014, 11:20

... Macro-averaging as- sumes that there is nothing intrinsically interesting about a nugget—it is simply a matter of a particular user with particular needs finding a particular nugget to be of interest. ... series to evaluate question answering system effectiveness. In Proc. of HLT/EMNLP 2005. 775 Proceedings of the 45th Annual Meeting of the Association of Computational Linguist...

Ngày tải lên: 20/02/2014, 12:20

... 11-amino-acid peptide containing only the basic a mino-acid cluster is highly ef®cient in mediating internalization of heterologou s proteins w hen fused at the N-terminal domain of these proteins ... appears unlikely. The number of arginine residues within the Tat peptide appeared to be the main determinant for main- taining a high translocating activity as pre viously shown by...

Ngày tải lên: 21/02/2014, 03:20

... were interrupted by two introns located in identical positions (Fig. 1B). The first intron included nucleotides 50–96 and the second intron included nucleotides 210–253 in each gene. Excluding introns ... longitudinal interactions formed by c-T1 and c-T2. Finally, c-T2 possesses a glycine at position 72 in place of consensus ⁄ c-T1 arginine (Fig. 4B¢). This substitution may ‘open’ the...

Ngày tải lên: 07/03/2014, 04:20

... all these kinetic findings are indicative of a different cata- lytic funnel in L 2 , having one allosteric ligand-binding site of predominant hydrophobicity. Binding of OAB in the substrate-binding site ... existence of two nonoverlapping inhibitor-binding sites, one of which is the substrate- binding site. An inhibition kinetic study with O-aminobenzoic acid, a mim- icking sub...

Ngày tải lên: 07/03/2014, 05:20

... of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72, 248–254. 40 Laemmli UK (1970) Cleavage of structural proteins during the assembly of head of ... the maintenance of a high- affinity CDNB-binding site. However, the substitu- tion E117K gives rise to mutants showing increased k cat values for CDNB, suggesting that Lys117 might p...

Ngày tải lên: 15/03/2014, 09:20

... residues of neighboring R3 is a major step for initiating filament formation. In contrast, the increase in ThS intensity was very slow in R2 (Fig. 2B), indicating that the aggregation mechanism of R2 ... Heparin-induced in vitro aggregation profiles of R3 with and without 1 m M dithio- threitol (A), of R2 with and without 1 m M dithiothreitol (B), and of seeded R3 (C) and...

Ngày tải lên: 23/03/2014, 12:20

... 64 Picard, Justin. 1999. Finding content-bearing terms using term similarities. In Proceedings of the Ninth Conference of the European Chapter of the Association for Computational Linguistics ... steps for achieving this goal). We suggest dividing the process of retrieving answers for such questions into two stages, with each stage focusing on modeling one aspect of a...

Ngày tải lên: 24/03/2014, 03:20