báo cáo khoa học: "Identification of circulating tumour cells in early stage breast cancer patients using multi marker immunobead RT-PCR" doc

... capable of detecting circulating tumour cells in early stage breast cancer patients. Introduction RT-PCR of peripheral blood mononuclear cells (PBM- NCs) using lineage-specific markers is the most ... properties of disseminating tumour cells. Nat Rev Cancer 2008, 8:329-340. 14. Hayes DF, Smerage J: Is there a role for circulating tumour cells in the ma...

Ngày tải lên: 10/08/2014, 22:20

... germin and germin-like gene s, which belong to the ancient superfamily of cupin proteins. The ABP20 contains a region which shared 40% of amino acid identity with a putative auxin binding site in ... GOING), zinc ion binding/LIM, ATP-binding cassette transporter MRP6 and unknown1 followed this profile in WT (Figure 4A-F). However, in general the expression of these genes remained...

Ngày tải lên: 12/08/2014, 03:21

... (AT(A) 28 TAA AG(A) 26 GGAAATAATAATTCA) insertion into exon 12 of FXI on chromosome 27. The insertion consists of long strings of adenine (A) bases and contains a stop codon that prevents the full-length protein from being made [9,11]. The ... eliminate this genetic disorder. Background Factor XI is one of more than a dozen proteins involved in blood clotting. FXI deficiency has bee...

Ngày tải lên: 12/08/2014, 18:22

... important role in clinical decision-mak- ing in receiving life-sustaining treatment and therefore in prog- nosis [27]. But before adaptation of prognostic models is Table 3 Performance of classification ... of mortality in all patients. However, little is known about the performance of these models in specific populations such as the very elderly. In addition, finding sub...

Ngày tải lên: 13/08/2014, 03:20

... anthocyanin sequestration, is a flavonoid- binding protein. Plant Physiol 123, 1561–1570. 24 Grotewold E (2004) The challenges of moving chemicals within and out of cells: insights into the transport of plant ... The occurrence of this effect was also investigated in carnation petal microsomes by preincu- bating them with antibody A in the presence of increasing concentrations...

Ngày tải lên: 20/02/2014, 01:20

... (Micromax cooled-CCD, Princeton Instrument, USA). Three sections per animal were examined and the number of MMC was counted in at least 10 randomly selected fields using an image analyzing software. Loss of intracellular ... these findings, it is still controversial whether MMC plays a key role in IBS. Several investigators have noted an increased number of MMC in terminal ileum...

Ngày tải lên: 07/08/2014, 18:20

... MSCs to cancer cells, nature of tumour cells and cancer stem cells, integrity of immune system, number of stem cell pas- sages and site of injection; all can affect the outcome of MSCs use in malignancy. ... 120-150 gm) were included in the study. Animals were inbred in the experimental animal unit, Faculty of Medicine, Cairo University. Rats were maintained accor...

Ngày tải lên: 10/08/2014, 10:21

... Our findings are consistent with previ- ous findings showing mRNA of PAR1 is expressed in pri- mary breast cancer tissue; mediates the invasive potential of certain breast cancer cell lines [13,15], ... expression in breast cancer patientsFigure 1 PAR1 expression in breast cancer patients. Western blots showing PAR and EGFR expression profiles of tumor biopsy sam...

Ngày tải lên: 18/06/2014, 15:20

... levels of apoptosis in control cells, not exposed to stress, were also significantly higher in HeLa cells than in HEK293 cells (Fig. 5A). Accord- ingly, when we examined the levels of hDlg protein in HEK293 ... the lack of hDlg degradation observed in this cell line. The low percentage of HEK293 cells undergoing apoptosis (compared with HeLa cells) , and the the lack...

Ngày tải lên: 23/03/2014, 06:20

... base of neck. In the middle of the trunk, two elliptical testes were arranged linearly. Posterior to the testes, six cement glands, pyriform in shape were arranged linearly, with ducts leading into ... testis arranged linearly in the middle or posterior portion of the body with six cement glands arranged linearly in the posterior portion of body. Van Cleave [9] noted that worm...

Ngày tải lên: 07/08/2014, 15:20