báo cáo khoa học: "Molecular prognostic markers for adult acute myeloid leukemia with normal cytogenetics" ppsx

... favorable for CR OR 20.8 BioMed Central Page 1 of 10 (page number not for citation purposes) Journal of Hematology & Oncology Open Access Review Molecular prognostic markers for adult acute myeloid ... Bloomfield CD: Independent confirmation of a prognostic gene-expression signature in adult acute myeloid leukemia with a normal karyotype: a Cancer and Leukem...

Ngày tải lên: 10/08/2014, 22:20

... and 96% identity with those of human and mouse, respectively. The deduced amino acid sequence of canine HIPK2 has also all domains’ sites compared with human and mouse HIPK2. Therefore, these structural ... and p53. In dogs, the gene therapy with p53 in cancer patients is in experimental stage. The study about the nucleotide sequence of canine HIPK2 was performed for the development o...

Ngày tải lên: 07/08/2014, 18:21

... and prognosis in adult acute myeloid leukemia. Hematology Am Soc Hematol Educ Program 2006, 169-77. 3. Dohner H, et al: Diagnosis and management of acute myeloid leukemia in adults: recommendations ... in New Zealand patients with acute myeloid leukemia. Cancer Genet Cytogenet 1983, 8(1):51-66. 14. Mrozek K, et al: Spectral karyotyping in patients with acute myeloid...

Ngày tải lên: 10/08/2014, 22:21

... presented with haemoptysis. Case presentation: A 45-year-old male presented with a 2-month history of episodic haemoptysis. A pedunculated growth from the inferior nasal turbinate was seen with fibre-optic ... com- monly seen within the maxillary sinus [3]. We hereby describe a case of a 45-year-old man with a supernumerary, ectopic molar tooth in the left maxil- lary antrum who initi...

Ngày tải lên: 11/08/2014, 20:20

... pretreated with dithiothrei- tol (C) or tunicamycin (D) and labeled with Pro-mix L-[ 35 S] in vitro labeling mix for 1 h. After labeling, microsomes were isolated and treated with (+) or without ... GmPDIL-2 with each specific antibody. Microsomes were isolated from cotyledons (150 mg beans) and treated with (+) or without ()) DSP. Proteins were extracted and immunoprecipitated wi...

Ngày tải lên: 07/03/2014, 05:20

... [4] and by comparison with the corresponding mouse [26] and human [27] genes. The sequence on either side of each exon–intron junction (Table 1) is conform to the GT/AG rule for splice donor and ... analysis using EcoRI restriction diges- tion is consistent with the presence of a single copy gene for xMGP (Fig. 3). However, Southern analysis with BamHI (Fig. 3 A) shows additional fr...

Ngày tải lên: 08/03/2014, 10:20

... K m values for ATP were in agree- ment with the results obtained for ADP in the forward reaction. It is worth noting that although changes in catalytic efficiency were not significant for GTP in ... affinities for other purine nucleotides such as GTP or ITP to those observed with ADP ⁄ ATP; however, the phosphoryla- tion transfer rates displayed with GTP or ITP are on average 50% l...

Ngày tải lên: 16/03/2014, 01:20

... determines the specificity for a dehydratase also became clear in this study. Why does DDR cross-form a complex with glycerol dehydratase, and why does GDR not cross-form a complex with diol dehydratase? ... subunits were per- formed with the EBI SSM [56] under the pairwise three- dimensional alignment mode. Buried molecular surface areas were calculated with the program CNS [57], f...

Ngày tải lên: 16/03/2014, 05:20

... EM1 with position restraints 10 000 500 0 EM2 with position restraints 20 000 500 12.5 MD1 with position restraints 25 000 of 0.5 fs 500 0 EM3 with position restraints 15 000 25 25.0 MD2 with ... second generation force field for the simulations of proteins, nucleic acids and organic molecules. J Am Chem Soc 117, 5179–5197. 33 Ponder JW & Case DA (2003) Force fields for protei...

Ngày tải lên: 16/03/2014, 10:20

... undergo normal e mbryo- genesis, but develop microvesicular hepatic steatosis within 4 d ays of b irth, dying by the end of two weeks with fatty liver [25]. Conditional gene knockout may therefore ... These kinetic parameters were also in agreement with previously reported values for other forms of AK [8]. Most tissues express more of one AK isoform than the other Quantitative immunob...

Ngày tải lên: 16/03/2014, 18:20