báo cáo khoa học: "Phase 1-2a multicenter dose-escalation study of ezatiostat hydrochloride liposomes for injection (Telintra®, TLK199), a novel glutathione analog prodrug in patients with myelodysplastic syndrome" doc
báo cáo khoa học: "Phase 1-2a multicenter dose-escalation study of ezatiostat hydrochloride liposomes for injection (Telintra®, TLK199), a novel glutathione analog prodrug in patients with myelodysplastic syndrome" doc
... grades. Pharmacokinetic data were analyzed with plasma concen- tration-time profiles constructed for each patient treated in phase 1. Summary statistics were generated for each individual and for ... each treatment group. Ezatiostat HCl Liposomes for Injection (TLK199) PharmacokineticsFigure 2 Ezatiostat HCl Liposomes for Injection (TLK199) Pharmacokinetics. Formatio...
Ngày tải lên: 10/08/2014, 22:20
Báo cáo khoa học: "Giant breast tumors: Surgical management of phyllodes tumors, potential for reconstructive surgery and a review of literature" potx
... significant masses on palpation. There was no palpable adenopathy in either of the axillary basins. Fine needle aspiration was performed during the initial visit and revealed highly atypical cells ... duration of which was unclear. On physical examination, the patient's left breast had a multilobulated and relatively firm mass that measured approximately 12 cm in diameter and e...
Ngày tải lên: 09/08/2014, 07:22
Báo cáo khoa học: Purification and structural study of the b form of human cAMP-dependent protein kinase inhibitor pdf
... 5¢-CCCCATATGATGAGGACAGATT CATCAAAAATG-3¢ and 5¢-CATGGATCCTCATTTT TCTTCATTTTGAGGC-3¢. The amplified PCR fragment was inserted into plasmid vector pET between the endo- nuclease sites NdeIandHindIII. ... Pharmacia Biotech Company. Isolation and sequencing of a cDNA clone encoding human PKIb A high quality cDNA library was constructed using human fetal brain poly (A + ) RNA by our laborato...
Ngày tải lên: 07/03/2014, 15:20
Báo cáo khoa học: Molecular cloning, expression and characterization of cDNA encoding cis-prenyltransferases from Hevea brasiliensis A key factor participating in natural rubber biosynthesis pdf
... (5¢-GCAAATGCAACTGGA AGCGG-3¢)andA1(5¢-ACAGCCTGCTAGCAAAGA GG-3¢) for amplification of HRT1, and primers S2 (5¢-GAAGAATCCTCTAAGGATAA-3¢)andA2(5¢-TA CAAGGATTAATCCCTTGC-3¢) for amplification of HRT2. ... brasiliensis A key factor participating in natural rubber biosynthesis Kasem Asawatreratanakul 1,2 , Yuan-Wei Zhang 1, *, Dhirayos Wititsuwannakul 3 , Rapepun Wititsuwannakul 4 , Seiji...
Ngày tải lên: 07/03/2014, 21:20
Báo cáo khoa học: An X-ray diffraction study of model membrane raft structures doc
... peak fitting performed using peakfit 4.12 (Systat Software Inc., Bangalore, India). Details of the peak fitting procedure are described in the Supporting information. The square root of integrated ... Mitsui K, Hatakeyama K, Matsushita M & Kanazawa H (2009) Saccharomyces cerevisiae Na + ⁄ H + antiporter Nha1p associates with lipid rafts and requires sphingo- lipid for stable local...
Ngày tải lên: 15/03/2014, 23:20
Báo cáo khoa học: S -Stereoselective piperazine-2-tert-butylcarboxamide hydrolase from Pseudomonas azotoformans IAM 1603 is a novel L-amino acid amidase doc
... been reported, LaaA from P. azotoformans IAM 1603 is the first L -amino acid amidase whose primary sequence is revealed. Acknowledgements WearegratefultoS.Iwamoto,R.KasaharaandA.Nakayama (Toyama Prefectural ... fol- lowing compounds were not substrates for the amidase: L -argininamide, L -asparaginamide, L -isoasparagine, L -glutaminamide, L -isoglutamine, glycinamide, L -histidinamide, L -l...
Ngày tải lên: 23/03/2014, 12:20
Báo cáo khoa học: "Spontaneous intratumoral bleeding and rupture of giant gastric stromal tumor ( 30 cm) in a young patient" pot
... margins associated with adjuvant therapy with imatinib mesylate remains the main modality of treatment for high risk GISTs. Background Gastrointestinal stromal tumor (GIST) is a generic name for ... in patients with an intraabdominal mass. Emergency local excision with negative margins associ- ated with adjuvant therapy with KIT tyrosine kinase inhib- World Journal of...
Ngày tải lên: 09/08/2014, 07:21
Báo cáo khoa học: " Intraoperative radiotherapy (IORT) combined with external beam radiotherapy (EBRT) for soft-tissue sarcomas – a retrospective evaluation of the Homburg experience in the years 1995–2007" pdf
... LE, Adhan M, Romestaing P, Chapet O, Isaac S, Gerard JP: Surgical management of retroperitoneal sarcomas associated with external and intraoperative radio- therapy. European journal of surgical ... Hospital and resulted in a his- topathologically radical resection in 15/38 pats. whereas in 12 patients the resection ended R1 and in 4 patients R2; in the remaining 7 patie...
Ngày tải lên: 09/08/2014, 10:20
báo cáo khoa học: " Stigma, social reciprocity and exclusion of HIV/AIDS patients with illicit drug histories: A study of Thai nurses'''' attitudes" pdf
... using NVivo software for analysing qualitative data and capable of providing basic quantitative analysis. The data were further explored using content analysis for the exploration of recurring ... rotations as part of their nurs- ing training. The other half of the sample was made up of qualified nurses who, after years of clinical experiences, took up postgraduate training at...
Ngày tải lên: 11/08/2014, 18:20
Báo cáo khoa học: "Two years follow-up study of the pain-relieving effect of gold bead implantation in dogs with hip-joint arthritis" docx
... Hielm-Bjorkman A, Raekallio M, Kuusela E, Saarto E, Markkola A, Tulamo RM: Double-blind evaluation of implants of gold wire at acupuncture points in the dog as a treatment for osteoar- thritis induced ... measurements and initial scores as covariate [16]. Matched-pairs ANOVA model was used for analysis within groups. For change within groups, cross-table analysis was per- for...
Ngày tải lên: 12/08/2014, 18:21