báo cáo khoa học: "Updates in Gastrointestinal Oncology – insights from the annual meeting of the American Society of Clinical Oncology" potx
báo cáo khoa học: "Updates in Gastrointestinal Oncology – insights from the annual meeting of the American Society of Clinical Oncology" potx
... neurop- athy in the OFF arm. The median OS in the OFF arm was 28 weeks, and that of the FF arm was 13 weeks, thereby fulfilling the study hypothesis. There was also a significant prolongation of PFS in the ... 6 of 13 (page number not for citation purposes) at the 2008 ASCO annual meeting indicates that progress in these cancers is forthcoming. Abstracts from...
Ngày tải lên: 10/08/2014, 22:20
báo cáo khoa học: "Updates in non-small cell lung cancer - insights from the 2009 45th annual meeting of the American Society of Clinical Oncology" potx
... Mirshahidi and Hsueh, Updates in non-small cell lung cancer - insights from the 2009 45th annual meeting of the American Society of Clinical Oncology Journal of Hematology & Oncology 2010, 3:18 Mirshahidi ... positive data from the ZODIAC trial. The important finding in this trial has demonstrated the improvement of PFS and RR from van- detanib...
Ngày tải lên: 10/08/2014, 22:21
Báo cáo khoa học: "Differences in vegetation cover resulting from various methods of site preparation for pine plantations in South Africa" potx
... surround- ing openings (eg, Taraxacum officinale). Frequencies of occurrence of the major species in the sample plots during the 3 post-harvesting surveys is shown in table II. In ... treatments included pitting, augering, rip- ping (subsoiling), and ripping and disk-ploughing. Pitting is the standard site preparation procedure in the regio...
Ngày tải lên: 08/08/2014, 19:21
báo cáo khoa học: " Intervening in global markets to improve access to HIV/AIDS treatment: an analysis of international policies and the dynamics of global antiretroviral medicines markets" potx
... awarded the majority of their pur- chases to one or two. The chosen manufacturers then typically dominate the market. These procurement poli- cies may discourage other producers from incurring the costs ... further consolidate the number of buyers. Whereas the original design of the GFATM placed medi- cine procurement in the hands of national principal recipients,...
Ngày tải lên: 11/08/2014, 14:21
Báo cáo khoa học: Dynamics driving function ) new insights from electron transferring flavoproteins and partner complexes pdf
... Severe GAII [73] – – 151-GGa. gtG-157 – – GAII [71] – – 269-ATAgtaGCA-271 – – GAII [71] – – 294-AGa. aag-321 – – GAII [71] – – 272-gaa aag-294 – – GAII [72] – – 478-del G (frameshift) – – GAII [73] b-ETF ... stabilization of the anio- nic semiquinone, most probably because of the loca- tion of the guanidinium group of...
Ngày tải lên: 07/03/2014, 05:20
Báo cáo khoa học: "Delineation in thoracic oncology: a prospective study of the effect of training on contour variability and dosimetric consequences" potx
... target coverage index (TCO) and the organs at risk (OAR) coverage index (OCO) [9-12]. The CO Index is the ratio of the minimum dose delivered in 98% of the volume of interest and the reference ... that incorporating a practical delineation workshop during training improves residents’ delineation. These two studies highlight the importance of practical and theoretical...
Ngày tải lên: 09/08/2014, 09:21
báo cáo khoa học: "First-in-class, first-in-human phase I results of targeted agents: Highlights of the 2008 American Society of Clinical Oncology meeting" pot
... XL765, and the survivin vaccine. Introduction This year, a myriad of novel agents were introduced by way of Phase I trials at the American Society of Clinical Oncology (ASCO) meeting, held in Chicago, ... revolutionizing the treatment of cancer – the use of biomarkers to select individual thera- pies for individual patients. Even from these preliminary phase...
Ngày tải lên: 10/08/2014, 22:20
Tài liệu Báo cáo khoa học: Changes in purine specificity in tandem GAF chimeras from cyanobacterial cyaB1 adenylate cyclase and rat phosphodiesterase 2 pptx
... (D) Interaction sites for cAMP in the structure of the cyaB2 GAF A domain. (E) Interaction sites for cAMP in the structure of the cyaB2 GAF B domain. Amino acids interacting with the purine moiety ... determine whether cNMP access and binding was abrogated or whether intramolecular signalling was impaired because of incorrect folding of the GAF ensemble in spite of...
Ngày tải lên: 19/02/2014, 02:20
Tài liệu Báo cáo khóa học: Mutations in the hydrophobic core and in the protein–RNA interface affect the packing and stability of icosahedral viruses doc
... involved in the protein–RNA and protein–protein interactions that mediate these functions [9,31,32,3 9–4 2]. Analysis of the effects of substitutions of key amino acids should ultimately provide information ... different from those of other simple icosahedral viruses [13]. The main chain of the protein subunit folds into a five stranded antiparallel b-sheet (strands bC–...
Ngày tải lên: 19/02/2014, 12:20
Tài liệu Báo cáo khoa học: A novel coupled enzyme assay reveals an enzyme responsible for the deamination of a chemically unstable intermediate in the metabolic pathway of 4-amino-3-hydroxybenzoic acid inBordetellasp. strain 10d doc
... shifts to 265 nm if the protein contains a flavin-type cofac tor [28]. We failed to identify the cofactor of the deaminase from strain 10d because the enzyme could not be purified in large enou gh quantities. ... analysis, and the determination of released ammonia. The coupled enzyme assay revealed the mechanism of the deamination reaction and the subsequent metabol...
Ngày tải lên: 19/02/2014, 16:20