báo cáo khoa học: "Journal of Hematology & Oncology BioMed Central Short report Open Access Detection of NPM1 exon 12 mutations and FLT3 – internal tandem duplications by high resolution melting analysis in normal karyotype acute myeloid leukemia" docx

... purposes) Journal of Hematology & Oncology Open Access Short report Detection of NPM1 exon 12 mutations and FLT3 – internal tandem duplications by high resolution melting analysis in normal karyotype acute ... abnormal melting Figure 1 Detection of NPM1 mutations and FLT3- ITD using high resolution melting analy...

Ngày tải lên: 10/08/2014, 22:20

... BioMed Central Page 1 of 2 (page number not for citation purposes) Journal of Hematology & Oncology Open Access Editorial Journal of hematology & oncology: A journal open to all Delong ... are accessible only to those with sub- scriptions. Journal of Hematology & Oncology aims to serve as an international platform for sharing laboratory and clinical...

Ngày tải lên: 10/08/2014, 22:20

... Dinapoli R, Kline R, Loeffler J, Farnan N: Single dose radiosurgical treatment of recurrent previously irradiated primary brain tumors and brain metastases: Final report of RTOG protocol 9 0–0 5. ... technologies. Inaccurate contouring leads to incorrect dosimetry, and poor quality treatment results in lower tumor control and increased toxicity [3]. During the national tr...

Ngày tải lên: 09/08/2014, 09:21

... of using calcium and magnesium, and one study also examined intermittent administration of oxali- platin in minimizing neurotoxicity from oxaliplatin. The Combined Oxaliplatin Neurotoxicity Prevention ... experimental elements, including early administration of mitomycin-C, inclusion of cisplatin and prolonged doxifluridine administration besides the intraperitoneal therapy. T...

Ngày tải lên: 10/08/2014, 22:20

... combinations on both the pET22b- and pEG276-based clones: H41A – SB82 and SB83, H41K – SB114 and SB115, H41C – SB116 and SB117, H41M – SB118 and SB119, D129A – SB101 and SB102, D129Q – SB103 and ... primers SB 112 and SB113. A hybrid NirF was made by introduction of the NirC signal sequence in front of NirF by two sequential inverse PCRs usin...

Ngày tải lên: 15/02/2014, 01:20

... TIAR. Co-immunoprecipitation assays revealed that ASF ⁄ SF2 A TIAR-flag Inputs IP Inputs IP Inputs IP Inputs IP + + – – +–+ ++++++ ++++++ – +–+ – +– +–+ – + –+ – +– ASF/SF2 hnRNP M DDX21 p68 BOIP-flag TIAR-flag BOIP-flag HA-p68 WB ... defective for RNA binding. Point mutations disrupting the RNA-binding capacity of any of the two RRMs led to the nuclear s...

Ngày tải lên: 16/02/2014, 15:20

... Analysis of serum insulin-like growth factor binding proteins using western blotting: use of the method for titration of the binding proteins and competi- tive binding studies. Anal Biochem 154, 13 8–1 43. M. ... resin and assayed for binding of [ 125 I]IGF-II (B) or [ 125 I]PMP-BSA (C). The lines in each graph indicate the amount of binding predicted if the wild-type...

Ngày tải lên: 18/02/2014, 08:20

... The N-terminal part of TIMPs is involved in binding to the active site of MMPs and hence prevents their action, whereas the C-terminal part can bind to proteins in the cell mem- brane and modulate ... a cystein residue in the prodomain and Zn 2+ in the active site of the catalytic domain. Two major types of endogenous inhibitors regulate the activity of MMPs; a 2 -macr...

Ngày tải lên: 18/02/2014, 11:20

... studied in considerable detail [1 0–1 3]. In archaea, the first committed step involves release of pyrophosphate and opening of the imidazole ring Keywords 2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5¢-phosphate ... lac repressor protein. Kanamycin and ampicillin were used to secure the maintenance of both plasmids in the host strain. Cloning of 2,5-diamino-6-ribitylamin...

Ngày tải lên: 18/02/2014, 18:20

... destabilization of the p53–DNA interaction (or even prevention of target recognition by the pro- tein). DNA binding of the C-terminally truncated p53( 1–3 63) protein In this work, we studied the effects of ... lacking the cisplatin-reactive motifs or containing multiple guanine doublets and ⁄ or triplets (Fig. 7), were used to check the in uence of cisplatin adducts in t...

Ngày tải lên: 19/02/2014, 05:20