báo cáo khoa học: "Isolation of specific and biologically active peptides that bind cells from patients with acute myeloid leukemia (AML)" doc
báo cáo khoa học: "Isolation of specific and biologically active peptides that bind cells from patients with acute myeloid leukemia (AML)" doc
... bind cells from leukemia patients Phage clones that bind to leukemia cells were isolated by incubating a library of M13 phage bearing 8 mer pep- tides with BM mononuclear cells from CML-BC patients. After ... screening, and in order to avoid iso- lating patient specific peptides, the screening and profiling were performed with cells from multiple pati...
Ngày tải lên: 10/08/2014, 22:20
Báo cáo khoa học: "Inducibility of the endogenous antibiotic peptide β-defensin 2 is impaired in patients with severe sepsis" pptx
... survi- vors and non-survivors of severe sepsis. Despite the limited number of patients, the statistical power of the comparison of hBD2 mRNA inducibility between patients with severe sepsis and controls ... imbalance occurring in patients with severe sepsis. The importance of plasmatic hBD2 for patients with severe sepsis is unclear. In particular, knowledge of th...
Ngày tải lên: 13/08/2014, 03:20
Báo cáo khoa học: Isolation, characterization, sequencing and crystal structure of charybdin, a type 1 ribosome-inactivating protein from Charybdis maritima agg. potx
... highly active and others inactive. If this is the case, the protein that we isolated and studied may be an inactive isoform, and the observed activity may be due to ‘impurities’ of another highly active ... the mechanism of action of the toxic enzyme [16,17]. It was found that replacement of Tyr (in ricin position 80) with Phe decreased activity by a factor of 15, a...
Ngày tải lên: 16/03/2014, 14:20
Báo cáo khoa học: "Isolation of Aspergillus spp. from the respiratory tract in critically ill patients: risk factors, clinical presentation and outcome" potx
... (COPD), immunosuppression and trans- plantation in the patients with Aspergillus infection, and a greater prevalence of solid neoplasms in the patients with Candida infection. With regard to risk factors ... before isolation of Aspergillus spp. was 32.1 ± 21.4 days. Previous use of fluconazole was recorded in eight of the 36 patients (22.2%) with isolation of Asper...
Ngày tải lên: 12/08/2014, 22:21
Tài liệu Báo cáo khoa học: Mechanisms of obesity and related pathologies: Androgen deficiency and endothelial dysfunction may be the link between obesity and erectile dysfunction pptx
... [10,11] suggested that the most prevalent form of MetS is associated with abdominal (visceral) obesity and that this type of obesity contributes to insulin resistance (IR) and the increased release of cytokines, ... sug- gested that obesity itself may be the underlying cause for a hypoandrogenic state. Kaplan et al. [55] examined testosterone levels in 864 subjects with a...
Ngày tải lên: 18/02/2014, 06:20
Tài liệu Báo cáo khoa học: Analysis of proteins and peptides on a chromatographic timescale by electron-transfer dissociation MS ppt
... 6271 dimethylation of Arg, monomethylation, dimethylation and trimethylation of Lys, acetylation and ubiquitina- tion of Lys, and phosphorylation of Ser and Thr [16– 18]. Combinations of these modifications ... Fragmentation scheme for production of ions of type c¢ and z¢ Æ by reaction of a low-energy electron with a multiply protonated peptide. ETD-MS analysis of...
Ngày tải lên: 18/02/2014, 16:20
Tài liệu Báo cáo khoa học: Binding of N- and C-terminal anti-prion protein antibodies generates distinct phenotypes of cellular prion proteins (PrPC) obtained from human, sheep, cattle and mouse doc
... intensities of the di- (d), mono- (j) and nonglycosylated isoform (m) of PrP C were quantified and calcu- lated as percentages of the total signal. The glycoforms of the pro- tein bands were analyzed ... indicated. (B) The glycoforms of the protein bands were analyzed by calcula- tion of the percentages of the di- (d), mono- (j) and nonglycosy- lated (m) isoform as arithmet...
Ngày tải lên: 19/02/2014, 02:20
Tài liệu Báo cáo khoa học: Role of K22 and R120 in the covalent binding of the antibiotic fosfomycin and the substrate-induced conformational change in UDP-N-acetylglucosamine enol pyruvyl transferase docx
... fosfomycin binding, and in view of the multitude of interactions, it was assumed that deletion of a single interaction would not lead to a complete loss of fosfomycin binding. Therefore it was argued that ... ligand binding. The loop region of the upper domain moves towards the active site of the enzyme, thus shielding the substrates (and ligands) from bulk solvent. A d...
Ngày tải lên: 19/02/2014, 13:20
Tài liệu Báo cáo khoa học: "Order of Subject and Predicate in Scientific Russia" pptx
... variety of classes of words. Almost 1/4 of the clauses contain no subject. The results of the above study indicate that the word order in scientific Russian is sufficiently different from that of ... 7.96% of the total. The word order was Subject - Predicate in all instances without exception. 3. The predicate slot was filled by an adjective in 496 instances, or 17....
Ngày tải lên: 19/02/2014, 19:20
Tài liệu Báo cáo khoa học: Role of cleavage and shedding in human thyrotropin receptor function and trafficking pdf
... extracellular and a b-transmembrane and intracellular subunits, held together by disulfide bonds. Moreover, part of the a-subunit of the receptor is shed from thyroid and transfected L cells. To understand ... removal of the unbound Ig, cells were washed three times with cold incubation medium, once with prewarmed incubation medium and incubated at 37 °C for various peri...
Ngày tải lên: 21/02/2014, 00:20