... in this system, and the involvement of a mechano-transduction pathway via the integrin/mitogen-acti-vated protein kinase (MAPK) pathway and of another signalingpathway via β-catenin was evaluated. ... Yokohama City, Kanagawa 236-0004, Japan4Department of Functional Biology, Kanagawa Dental College, 82 Inaokachyo, Yokosuka City, Kanagawa 238-8580, Japan5Department of Environment and Information ... functional interaction between the PI3K/Akt pathway and Wnt/β-catenin signaling, LIPUSmay activate β-catenin signaling via the PI3K/Akt pathway. Asindicated in Figure 4c,d, the nuclear localization...