Báo cáo y học: "Non- medical prescribing in Australasia and the UK: the case of podiatry" ppsx
Báo cáo y học: "Non- medical prescribing in Australasia and the UK: the case of podiatry" ppsx
... practi-tioners in New Zealand and provide recommendationsto the Minister of Health, until it was disbanded in 2006 and taken over by the Ministry of Health.Podiatry in the UK and Australasia In both Australasia ... development of prescribing in podiatry in both Australasia and the UK enables an analysis of the impact of health policy reformson the use of, and access to, medicines by podiatrists. The advent of ... part of the changi ng landscape of modern professionalism , it is alsopremature to s uggest that the authority of medicine in influencing and determining the content of work of otherhealthprofessionsisatanend.Newmodesofprescribing...
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Báo cáo y học: " Non-invasive stroke volume measurement and passive leg raising predict volume responsiveness in medical ICU patients: an observational cohort study"
... par-ticipated in drafting the manuscript, and performed statisticalanalysis. WI had full access to all of the data in the study and takes responsibility for the integrity of the data and the accu-racy of ... may have facilitatedsuccessful measurements in many of these patients. Second, the majority of patients enrolled in our study had sepsis orhypovolemia as the etiology of their circulatory insufficiency.This ... during end-expiratory occlusion of the ventilator as well as changes in car-diac index during PLR were examined. An increase in cardiacindex of 10% or more during PLR predicted an increase in...
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Báo cáo y học: "Binge eating symptomatology in overweight and obese patients with schizophrenia: a case control study" ppt
... binge eatingsymptomatology may play an important role in the initi-ation and maintenance of the WG phenomenon observed in at least part of patients with schizophrenia. Finally,management of ... in psychotic patients treated by clozapine orolanzapine, especially in the high body mass index (BMI)subgroup [3]. The purpose of this study is to assess binge eating symp-tomatology in a ... controls and the correlation nature of this study, we cannot caus-ally link intake of antipsychotic drugs, BED, BS and WG.Limitations of this study included the small number of controls in regard...
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Báo cáo y học: "Gene expression profiling in murine autoimmune arthritis during the initiation and progression of joint inflammation" pps
... expression profile is extremely complexowing to the diversity of cell types involved in the pathology and the polygenic character of the autoimmune disease [1-5]. The overall picture of molecular interactions ... large variety of cell types(cells of the immune system and of synovial joints) involved in autoimmune arthritic processes, and the extreme geneticheterogeneity of the human population. The present ... compounds to induce arthritis [6,21-23]. Despite the usefulness of the information provided by these studies, the early gene expression events at the site of inflammation(joint and synovium) and the...
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Báo cáo y học: "Bone morphogenetic proteins in destructive and remodeling arthritis" pdf
... [41]. In normalsynovium, BMP4 and BMP5 positive cells were found mainly in the lining layer, whereas in RA these cells were morescattered.It is noteworthy that the presence of BMPs in the synovium ... distinctmechanisms of disease. In the joint, these include the development and persistence of an inflammatory and immunereaction, the activation of tissue destructive enzymes and cells, and the suppression ... formation. Interestingly, osteo-phytes induced by BMP2 injection were found predominantly in the regions where the growth plate met the joint space,whereas TGFβ-induced osteophytes originated from...
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Báo cáo y học: "Catabolic cytokine expression in degenerate and herniated human intervertebral discs: IL-1β and TNFα expression profile Christine Lyn Le Maitre, Judith Alison Hoyland and Anthony J Freemont" ppsx
... vessels. Stainingwas particularly prominent in the cytoplasm of the chondro-cyte-like cells of the NP and IAF, with significantly lower num-bers of cells in the OAF showing immunopositivity for ... Freemont AJ, Hoyland JA: A preliminary in vitrostudy into the use of IL-1Ra gene therapy for the inhibition of intervertebral disc degeneration. Int J Exp Pathol 2006,87:17-28.Available online http://arthritis-research.com/content/9/4/R77Page ... human intervertebral discs: IL-1β and TNFα expression profileChristine Lyn Le Maitre, Judith Alison Hoyland and Anthony J FreemontTissue Injury and Repair Group, School of Medicine, Faculty of Medical...
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Báo cáo y học: " Coronary arterial calcification in rheumatoid arthritis: comparison with the Multi-Ethnic Study of Atherosclerosis" pps
... nature of the analysis, and the discrepancymay be the result of random variability. Importantly, a singlemeasurement of inflammatory cytokines is not representative of the total inflammatory burden ... coro-nary plaques, thereby precipitating acute thrombosis and clinical CV events [13]. Interestingly, atherosclerotic plaque and rheumatoid synovium share an array of inflammatory cells and cytokines ... glucocorticoids and nonsteroidal anti-inflammatorydrugs), and the debilitating effect of joint pain and stiffness onphysical activity and fitness. In most studies of CVD in RA, differences in the prevalence...
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Báo cáo y học: "Progesterone - new therapy in mild carpal tunnel syndrome? Study design of a randomized clinical trial for local therapy" pptx
... paraesthesiae (numbness, tingling) and pain in the hand distribution of the median nerve, more oftenoccurring during night or in early morning waking up the patients. There may be also sensory loss ... may promote myelination by activating the expression of genes coding for transcription factors and/ or for myelin proteins [36,37] and/ or indirectly toregulate myelin formation by influencing ... expression in neurons and may promote neuroregeneration by sev-eral different actions by reducing inflammation, swelling and apoptosis, thereby increasing the survival of neurons, and by promoting the...
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Báo cáo y học: "Intra-articular hyaluronan (hyaluronic acid) and hylans for the treatment of osteoarthritis: mechanisms of action" pps
... E2(PGE2) and bradykinin synthesis, since HAinhibited their synthesis in a MW-dependent manner [16].Further, HA has been shown to induce analgesia in abradykinin-induced model of joint pain in rats ... synthesis [29,41]. The production of NO, another inflammatory mediator syn-thesized by the cartilage in OA and well documented in experimental OA, is stimulated by the proinflammatorycytokines ... by their proen-zymes, or decreased activity of their inhibitors [29]. Pro-inflammatory cytokines, including IL-1, TNF-α, IL-17, and IL-18, increase synthesis of MMPs, decrease MMPenzyme inhibitors,...
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Báo cáo y học: "Response to commentary by Dixon and Silman on the systematic review and meta-analysis by Bongartz et al" doc
... underestimate the true risk for seriousinfection in treated compared with control patients. In practice, lack of efficacy with the standard dose of 3 mg/kg of infliximab results in many patients using ... anti-TNFmonoclonal antibody therapy in rheumatoid arthritis and risk of malignancy and serious infection? Commentary on the meta-analysis by Bongartz et al. Arthritis Res Ther 2006, 8:111.LetterResponse ... dose-effectcriterion for causality. The low risk in the comparison group may be real, the result of chance, or due to an as yet unclear systematic design oranalysis flaw of all included randomized controlled...
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